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Biosimilars Topic Center

Featured

Stephen Speicher, MD
Videos
03/01/2024

Featuring Stephen V. Speicher, MD, MS

Featuring Stephen V. Speicher, MD, MS...
Stephen V. Speicher, MD, MS, discusses his upcoming AMCCBS poster presentation titled “Technology for Substituting Biosimilars to Improve Practice Efficiency and Financial Health.”
Stephen V. Speicher, MD, MS, discusses his upcoming AMCCBS poster presentation titled “Technology for Substituting Biosimilars to Improve Practice Efficiency and Financial Health.”
Stephen V. Speicher, MD, MS,...
03/01/2024
Journal of Clinical Pathways
Andre Harvin, PharmD, MS, MBA
Videos
03/28/2023
Andre Harvin, PharmD, MS, MBA, discusses controlling costs in the business of oncology through biosimilar use.
Andre Harvin, PharmD, MS, MBA, discusses controlling costs in the business of oncology through biosimilar use.
Andre Harvin, PharmD, MS, MBA,...
03/28/2023
Journal of Clinical Pathways
James Gelfand, JD
Videos
10/14/2022
James Gelfand, JD, The ERISA Industry Committee, discusses achieving optimal, value-driven patient care through pharmacy benefit managers, and changes in plan transparency for payers and patients at the 2022 Oncology Clinical Pathways...
James Gelfand, JD, The ERISA Industry Committee, discusses achieving optimal, value-driven patient care through pharmacy benefit managers, and changes in plan transparency for payers and patients at the 2022 Oncology Clinical Pathways...
James Gelfand, JD, The ERISA...
10/14/2022
Journal of Clinical Pathways
Conference Coverage
10/01/2022
At the 2022 ASCO Quality Care Symposium, Ives and colleagues concluded that therapeutic interchange is an effective way to reduce total cost of care while maintaining the quality of care in the Oncology Care Model.
At the 2022 ASCO Quality Care Symposium, Ives and colleagues concluded that therapeutic interchange is an effective way to reduce total cost of care while maintaining the quality of care in the Oncology Care Model.
At the 2022 ASCO Quality Care...
10/01/2022
Journal of Clinical Pathways
Research Reports
08/15/2022
Dr Hamilton and colleagues outline how eviCore Healthcare offered the option for payer clients to implement a biosimilar preferencing policy, analyzing how this policy affected the rate of biosimilar use and costs.
Dr Hamilton and colleagues outline how eviCore Healthcare offered the option for payer clients to implement a biosimilar preferencing policy, analyzing how this policy affected the rate of biosimilar use and costs.
Dr Hamilton and colleagues...
08/15/2022
Journal of Clinical Pathways
Puneeth Indurlal, MD, MS
Videos
07/12/2022
Puneeth Indurlal, MD, MS, describes his study on the utilization and financial impact of abiraterone therapeutic interchange in The Network during an Oncology Care Model performance period, a value-based care program from Medicare that...
Puneeth Indurlal, MD, MS, describes his study on the utilization and financial impact of abiraterone therapeutic interchange in The Network during an Oncology Care Model performance period, a value-based care program from Medicare that...
Puneeth Indurlal, MD, MS,...
07/12/2022
Journal of Clinical Pathways
Conference Coverage
07/06/2022
Findings from a recent real-world study suggest that use of an integrated electronic health record to standardize biosimilar utilization in oncology may reduce costs, without compromising quality and safety in care. 
Findings from a recent real-world study suggest that use of an integrated electronic health record to standardize biosimilar utilization in oncology may reduce costs, without compromising quality and safety in care. 
Findings from a recent...
07/06/2022
Journal of Clinical Pathways
Conference Coverage
06/14/2022
Researchers at the 2022 ASCO Annual Meeting estimated the impact of biosimilar substitution on financial risk to providers in oncology value-based payments by applying simulation approaches to model the episode framing, pricing, and risk...
Researchers at the 2022 ASCO Annual Meeting estimated the impact of biosimilar substitution on financial risk to providers in oncology value-based payments by applying simulation approaches to model the episode framing, pricing, and risk...
Researchers at the 2022 ASCO...
06/14/2022
Journal of Clinical Pathways
News
06/12/2022
PEG biosimilars may be able to optimize febrile neutropenia management among patients with intermediate-to-high risk febrile neutropenia while minimizing costs.
PEG biosimilars may be able to optimize febrile neutropenia management among patients with intermediate-to-high risk febrile neutropenia while minimizing costs.
PEG biosimilars may be able to...
06/12/2022
Journal of Clinical Pathways
News
06/09/2022
A research group in Denmark determined that median progression-free-survival with SB3 was comparable with that of reference trastuzumab for patients with HER2-positive metastatic breast cancer treated with chemotherapy.
A research group in Denmark determined that median progression-free-survival with SB3 was comparable with that of reference trastuzumab for patients with HER2-positive metastatic breast cancer treated with chemotherapy.
A research group in Denmark...
06/09/2022
Journal of Clinical Pathways
News
06/09/2022
This study finds that US oncologists have adopted switching between the bevacizumab reference product and bevacizumab biosimilars as well as using bevacizumab-bvzr in chemotherapy combination regimens.
This study finds that US oncologists have adopted switching between the bevacizumab reference product and bevacizumab biosimilars as well as using bevacizumab-bvzr in chemotherapy combination regimens.
This study finds that US...
06/09/2022
Journal of Clinical Pathways

Expert Insights

Gary Lyman, MD
Interview
08/30/2018
Gary Lyman, MD, MPH, explains the process of bringing oncology biosimilars to market and their potential uptake in clinical practice as well as pathways.
Gary Lyman, MD, MPH, explains the process of bringing oncology biosimilars to market and their potential uptake in clinical practice as well as pathways.
Gary Lyman, MD, MPH, explains...
08/30/2018
Journal of Clinical Pathways
Interview
10/30/2024
Learn about research developments in 1L therapy for NSCLC patients with EGFR mutations and how outcomes may impact coverage and reimbursement decisions for insurers.
Learn about research developments in 1L therapy for NSCLC patients with EGFR mutations and how outcomes may impact coverage and reimbursement decisions for insurers.
Learn about research...
10/30/2024
Journal of Clinical Pathways
JB
Interview
10/25/2024
Learn about recent advancements in CLL treatment including the potential approval of new combination therapies and the evolving landscape of targeted therapies.
Learn about recent advancements in CLL treatment including the potential approval of new combination therapies and the evolving landscape of targeted therapies.
Learn about recent advancements...
10/25/2024
Journal of Clinical Pathways
Jessica Paulus, ScD
Interview
10/23/2024
In this interview, Jessica Paulus, ScD, senior director of real-world research at Ontada, discusses trends in advanced non–small cell and small cell lung cancer diagnoses, the impact of the COVID-19 pandemic on screening, and the need for...
In this interview, Jessica Paulus, ScD, senior director of real-world research at Ontada, discusses trends in advanced non–small cell and small cell lung cancer diagnoses, the impact of the COVID-19 pandemic on screening, and the need for...
In this interview, Jessica...
10/23/2024
Journal of Clinical Pathways
Edward R. (Ted) Arrowsmith
Interview
10/10/2024
Join us as a guest expert discusses the evolving role of clinical pathways in guiding treatment decisions for non-small cell lung cancer in the era of precision medicine and targeted therapies, emphasizing the importance of patient-focused...
Join us as a guest expert discusses the evolving role of clinical pathways in guiding treatment decisions for non-small cell lung cancer in the era of precision medicine and targeted therapies, emphasizing the importance of patient-focused...
Join us as a guest expert...
10/10/2024
Journal of Clinical Pathways
Puneeth Indurlal
Interview
08/20/2024
Learn about the health-related social needs of patients with cancer, common types of distress reported by patients, and how assessment tools can inform the development of support services.
Learn about the health-related social needs of patients with cancer, common types of distress reported by patients, and how assessment tools can inform the development of support services.
Learn about the health-related...
08/20/2024
Journal of Clinical Pathways
Gunjan Sharma
Interview
07/10/2024
US Oncology Network analyst Gunjan Sharma shares insights on the impact of health-related social needs, Beer’s criteria medication prescribing patterns, and how research can inform the development of support services for patients with cancer.
US Oncology Network analyst Gunjan Sharma shares insights on the impact of health-related social needs, Beer’s criteria medication prescribing patterns, and how research can inform the development of support services for patients with cancer.
US Oncology Network analyst...
07/10/2024
Journal of Clinical Pathways
Stephen Colvill, MBA
Conference Coverage
07/08/2024
Stephen Colvill, MBA, discusses how collaboration, proactive strategies, and technology can help prevent drug shortages.
Stephen Colvill, MBA, discusses how collaboration, proactive strategies, and technology can help prevent drug shortages.
Stephen Colvill, MBA, discusses...
07/08/2024
Journal of Clinical Pathways
Paul Fu, MD
Interview
06/17/2024
Paul Fu Jr, MD, MPH, City of Hope National Medical Center
Paul Fu Jr, MD, MPH, discusses the benefits of using technology to assist health team communication practices.
Paul Fu Jr, MD, MPH, discusses the benefits of using technology to assist health team communication practices.
Paul Fu Jr, MD, MPH, discusses...
06/17/2024
Journal of Clinical Pathways
Interview
05/28/2024

 Ryan Motte, PharmD, CSP, Shields Health Solutions

 Ryan Motte, PharmD, CSP, Shields Hea...
Ryan Motte, PharmD, discusses how oncology drug shortages have impacted patients with chronic lymphocytic leukemia.
Ryan Motte, PharmD, discusses how oncology drug shortages have impacted patients with chronic lymphocytic leukemia.
Ryan Motte, PharmD, discusses...
05/28/2024
Journal of Clinical Pathways
Shaalan Beg, MD
Interview
05/20/2024
Shaalan Beg, MD, MBA, FASCO
Shaalan Beg, MD, MBA, FASCO, describes some of the recent advancements in the treatment of chronic lymphocytic leukemia (CLL).
Shaalan Beg, MD, MBA, FASCO, describes some of the recent advancements in the treatment of chronic lymphocytic leukemia (CLL).
Shaalan Beg, MD, MBA, FASCO,...
05/20/2024
Journal of Clinical Pathways

Newsfeed

News
06/12/2022
PEG biosimilars may be able to optimize febrile neutropenia management among patients with intermediate-to-high risk febrile neutropenia while minimizing costs.
PEG biosimilars may be able to optimize febrile neutropenia management among patients with intermediate-to-high risk febrile neutropenia while minimizing costs.
PEG biosimilars may be able to...
06/12/2022
Journal of Clinical Pathways
News
06/09/2022
A research group in Denmark determined that median progression-free-survival with SB3 was comparable with that of reference trastuzumab for patients with HER2-positive metastatic breast cancer treated with chemotherapy.
A research group in Denmark determined that median progression-free-survival with SB3 was comparable with that of reference trastuzumab for patients with HER2-positive metastatic breast cancer treated with chemotherapy.
A research group in Denmark...
06/09/2022
Journal of Clinical Pathways
News
06/09/2022
This study finds that US oncologists have adopted switching between the bevacizumab reference product and bevacizumab biosimilars as well as using bevacizumab-bvzr in chemotherapy combination regimens.
This study finds that US oncologists have adopted switching between the bevacizumab reference product and bevacizumab biosimilars as well as using bevacizumab-bvzr in chemotherapy combination regimens.
This study finds that US...
06/09/2022
Journal of Clinical Pathways
News
05/11/2022
Study findings show that results of rigorous clinical evaluation of cancer drug biosimilars were statistically indistinguishable when compared with the results of evaluations of the reference drug across subgroups of drugs, cancer types, and...
Study findings show that results of rigorous clinical evaluation of cancer drug biosimilars were statistically indistinguishable when compared with the results of evaluations of the reference drug across subgroups of drugs, cancer types, and...
Study findings show that results...
05/11/2022
Journal of Clinical Pathways
News
04/14/2022
Biosimilar HD201 demonstrates equal efficacy to referent trastuzumab in total pathological complete response and safety in ERBB2–positive breast cancer, according to results from the TROIKA trial.
Biosimilar HD201 demonstrates equal efficacy to referent trastuzumab in total pathological complete response and safety in ERBB2–positive breast cancer, according to results from the TROIKA trial.
Biosimilar HD201 demonstrates...
04/14/2022
Journal of Clinical Pathways
News
03/07/2022
Study findings show that trastuzumab biosimilars are safe and effective compared to the reference drug and improve patients' accessibility to breast cancer treatment.
Study findings show that trastuzumab biosimilars are safe and effective compared to the reference drug and improve patients' accessibility to breast cancer treatment.
Study findings show that...
03/07/2022
Journal of Clinical Pathways
News
02/25/2022
Findings from a recent update on currently approved oncology biosimilars suggests that the use of biosimilars might provide competitive, lower-cost alternatives to biologics used in oncology.
Findings from a recent update on currently approved oncology biosimilars suggests that the use of biosimilars might provide competitive, lower-cost alternatives to biologics used in oncology.
Findings from a recent update on...
02/25/2022
Journal of Clinical Pathways
News
02/21/2022
Study findings reveal primary prophylaxis with biosimilar filgrastim-sndz is cost-effective in patients with cancer at intermediate risk for febrile neutropenia.
Study findings reveal primary prophylaxis with biosimilar filgrastim-sndz is cost-effective in patients with cancer at intermediate risk for febrile neutropenia.
Study findings reveal primary...
02/21/2022
Journal of Clinical Pathways
News
02/11/2022
Conversion to biosimilar pegfilgrastim-cbqv for neutropenia prophylaxis can generate potential cost-savings and provide budget-neutral expanded access to FOLFIRINOX treatment for patients with metastatic pancreatic cancer.
Conversion to biosimilar pegfilgrastim-cbqv for neutropenia prophylaxis can generate potential cost-savings and provide budget-neutral expanded access to FOLFIRINOX treatment for patients with metastatic pancreatic cancer.
Conversion to biosimilar...
02/11/2022
Journal of Clinical Pathways
News
02/10/2022
Study findings suggest biosimilar intravenous trastuzumab-dkst is cost-efficient over reference intravenous and subcutaneous trastuzumab in metastatic breast cancer.
Study findings suggest biosimilar intravenous trastuzumab-dkst is cost-efficient over reference intravenous and subcutaneous trastuzumab in metastatic breast cancer.
Study findings suggest...
02/10/2022
Journal of Clinical Pathways
News
11/13/2024
Combining immunotherapy with chemotherapy in the treatment of advanced endometrial cancer, particularly in cases of mismatch repair deficiency, has shown promising results in improving progression-free and overall survival outcomes according...
Combining immunotherapy with chemotherapy in the treatment of advanced endometrial cancer, particularly in cases of mismatch repair deficiency, has shown promising results in improving progression-free and overall survival outcomes according...
Combining immunotherapy with...
11/13/2024
Journal of Clinical Pathways
News
11/12/2024
Just 41% of oncology practice groups offer a general survivorship clinic for cancer survivors, according to a study published online in JNCI Cancer Spectrum.
Just 41% of oncology practice groups offer a general survivorship clinic for cancer survivors, according to a study published online in JNCI Cancer Spectrum.
Just 41% of oncology practice...
11/12/2024
Journal of Clinical Pathways
News
11/08/2024
A comprehensive international consensus program has provided vital clinical recommendations to enhance the treatment landscape for myelofibrosis (MF).
A comprehensive international consensus program has provided vital clinical recommendations to enhance the treatment landscape for myelofibrosis (MF).
A comprehensive international...
11/08/2024
Journal of Clinical Pathways
News
11/06/2024
According to a study published in Nature, endometrial cancer (EC) cases are on the rise, and 10% to 20% of patients with EC experience distant recurrence. In this study, in researchers aimed to predict distant recurrence of EC to improve...
According to a study published in Nature, endometrial cancer (EC) cases are on the rise, and 10% to 20% of patients with EC experience distant recurrence. In this study, in researchers aimed to predict distant recurrence of EC to improve...
According to a study published...
11/06/2024
Journal of Clinical Pathways
News
10/30/2024
Addressing socioeconomic disparities may improve survival for patients with myelofibrosis, according to a study published in Annals of Hematology.
Addressing socioeconomic disparities may improve survival for patients with myelofibrosis, according to a study published in Annals of Hematology.
Addressing socioeconomic...
10/30/2024
Journal of Clinical Pathways
News
10/25/2024
A systematic review and meta-analysis found a significant association between hypertension and an increased risk of endometrial cancer.
A systematic review and meta-analysis found a significant association between hypertension and an increased risk of endometrial cancer.
A systematic review and...
10/25/2024
Journal of Clinical Pathways
News
10/25/2024
Abemaciclib, a CDK4/6 inhibitor used in breast cancer treatment, shows promise in targeting novel mechanisms in endometrial cancer for potential therapeutic benefits in cases of recurrence, particularly in estrogen receptor-positive patients.
Abemaciclib, a CDK4/6 inhibitor used in breast cancer treatment, shows promise in targeting novel mechanisms in endometrial cancer for potential therapeutic benefits in cases of recurrence, particularly in estrogen receptor-positive patients.
Abemaciclib, a CDK4/6 inhibitor...
10/25/2024
Journal of Clinical Pathways
News
10/21/2024
Pembrolizumab combined with adjuvant carboplatin-paclitaxel significantly improves disease-free survival in patients with high-risk mismatch repair-deficient endometrial cancer, according to a study published in the Journal of Clinical...
Pembrolizumab combined with adjuvant carboplatin-paclitaxel significantly improves disease-free survival in patients with high-risk mismatch repair-deficient endometrial cancer, according to a study published in the Journal of Clinical...
Pembrolizumab combined with...
10/21/2024
Journal of Clinical Pathways
News
10/17/2024
A study published in JAMA Oncology found that Black women are more likely to receive false negative results from transvaginal ultrasounds for endometrial cancer compared to White women, highlighting the need for improved diagnostic methods...
A study published in JAMA Oncology found that Black women are more likely to receive false negative results from transvaginal ultrasounds for endometrial cancer compared to White women, highlighting the need for improved diagnostic methods...
A study published in JAMA...
10/17/2024
Journal of Clinical Pathways
News
10/16/2024
A study published in Advances in Therapy shows that momelotinib significantly improves anemia and related symptoms in patients with myelofibrosis, particularly those previously treated with ruxolitinib.
A study published in Advances in Therapy shows that momelotinib significantly improves anemia and related symptoms in patients with myelofibrosis, particularly those previously treated with ruxolitinib.
A study published in Advances in...
10/16/2024
Journal of Clinical Pathways

From the Journal

Research Reports
08/15/2022
Dr Hamilton and colleagues outline how eviCore Healthcare offered the option for payer clients to implement a biosimilar preferencing policy, analyzing how this policy affected the rate of biosimilar use and costs.
Dr Hamilton and colleagues outline how eviCore Healthcare offered the option for payer clients to implement a biosimilar preferencing policy, analyzing how this policy affected the rate of biosimilar use and costs.
Dr Hamilton and colleagues...
08/15/2022
Journal of Clinical Pathways
Research Reports
10/15/2018
Abstract: Eight years have passed since Congress enacted the Biologics Price Competition and Innovation Act (BPCIA) of 2010. Since then, 12 biosimilars have received approval from the Food and Drug Administration,...
Abstract: Eight years have passed since Congress enacted the Biologics Price Competition and Innovation Act (BPCIA) of 2010. Since then, 12 biosimilars have received approval from the Food and Drug Administration,...
...
10/15/2018
Journal of Clinical Pathways
Research Reports
09/13/2018
Abstract: Biosimilars are hypothesized to contribute to lowering health care costs by entering the market at a discounted price compared with their reference biologics. Until recently, only filgrastim biosimilars...
Abstract: Biosimilars are hypothesized to contribute to lowering health care costs by entering the market at a discounted price compared with their reference biologics. Until recently, only filgrastim biosimilars...
...
09/13/2018
Journal of Clinical Pathways
Perspectives
10/01/2024
In this third installment of a three-part series on decision support tools and shared decision-making, Christine Wilson, MA, MS, and colleagues describe how patients with­in three diverse communities who are living with cancer understand and...
In this third installment of a three-part series on decision support tools and shared decision-making, Christine Wilson, MA, MS, and colleagues describe how patients with­in three diverse communities who are living with cancer understand and...
In this third installment of a...
10/01/2024
Journal of Clinical Pathways
Perspectives
10/01/2024
This pilot study provides a brief literature review on users, uses, and a recent electronic survey to de­termine how users use clinical pathways along with their feedback around their value.
This pilot study provides a brief literature review on users, uses, and a recent electronic survey to de­termine how users use clinical pathways along with their feedback around their value.
This pilot study provides a...
10/01/2024
Journal of Clinical Pathways
Research Reports
08/19/2024
This study explores how clinical pathways can help reduce time to treatment delays while improving health care quality, lowering direct and indirect health care costs, reducing patient financial toxicity, and achieving greater patient,...
This study explores how clinical pathways can help reduce time to treatment delays while improving health care quality, lowering direct and indirect health care costs, reducing patient financial toxicity, and achieving greater patient,...
This study explores how clinical...
08/19/2024
Journal of Clinical Pathways
From the Field
08/15/2024
In this report, researchers discuss a real-world study of treatment selection patterns across American Oncology Network medical oncologists, which analyzed pathway adherence rates before and after a pilot project where Evolent level 1...
In this report, researchers discuss a real-world study of treatment selection patterns across American Oncology Network medical oncologists, which analyzed pathway adherence rates before and after a pilot project where Evolent level 1...
In this report, researchers...
08/15/2024
Journal of Clinical Pathways
Perspectives
06/26/2024
This article describes how congruent solutions for treatment options can be achieved if the objectives of precision medicine and treatment pathways are aligned.
This article describes how congruent solutions for treatment options can be achieved if the objectives of precision medicine and treatment pathways are aligned.
This article describes how...
06/26/2024
Journal of Clinical Pathways
From the Field
06/03/2024
This report explores the transformative impact of artificial intelligence (AI) in health care, emphasizing its potential paradigm shift and current deployment in oncology.
This report explores the transformative impact of artificial intelligence (AI) in health care, emphasizing its potential paradigm shift and current deployment in oncology.
This report explores the...
06/03/2024
Journal of Clinical Pathways
Research Reports
06/03/2024
Sabree C. Burbage, PharmD
Dexter Waters, MSPH
Carmine Rossi, PhD
Frederic Kinkead, MA
Erik Muser, PharmD
Lorie Ellis, PhD
Patrick Lefebvre, MA
Dominic Pilon, MA
This study describes prostate-specific antigen (PSA) outcomes and clinical surveillance patterns among patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) receiving next-generation androgen receptor inhibitors (ARIs)...
This study describes prostate-specific antigen (PSA) outcomes and clinical surveillance patterns among patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) receiving next-generation androgen receptor inhibitors (ARIs)...
This study describes...
06/03/2024
Journal of Clinical Pathways
From the Field
06/03/2024
This paper provides insights and perspective from each constituent involved in shaping health care payment and delivery throughout the US.
This paper provides insights and perspective from each constituent involved in shaping health care payment and delivery throughout the US.
This paper provides insights and...
06/03/2024
Journal of Clinical Pathways
Research Reports
02/21/2024
In a recent study, Christi Ann Hayes, MD, and colleagues aimed to define patient-reported outcome measures in patients receiving hematopoietic stem cell transplant.
In a recent study, Christi Ann Hayes, MD, and colleagues aimed to define patient-reported outcome measures in patients receiving hematopoietic stem cell transplant.
In a recent study, Christi Ann...
02/21/2024
Journal of Clinical Pathways
From the Field
02/12/2024
Rebecca A. Previs, MD, et al provide an overview of current genomic testing methodologies and offer guidelines on best practices for tissue stewardship and preanalytic practices for successful comprehensive genomic profiling.
Rebecca A. Previs, MD, et al provide an overview of current genomic testing methodologies and offer guidelines on best practices for tissue stewardship and preanalytic practices for successful comprehensive genomic profiling.
Rebecca A. Previs, MD, et al...
02/12/2024
Journal of Clinical Pathways