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American Diabetes Association (ADA) 74th Scientific Sessions
June 13-17, 2014
San Francisco, CA
G-Pen, a new rescue therapy under development could avoid the step of reconstitution prior to administration in patients experiencing an episode of hypoglycemia. The results of a phase 2 safety study of the G-pen was presented at the ADA meeting.
During a poster session at the ADA meeting, researchers presented the results of their study, which examined dual therapy that added saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, or dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2), to metformin, as well as triple therapy that added both saxagliptin and dapagliflozin to metformin. The rationale for this latter combination was that DPP-4 inhibitors and SGLT2s have complementary mechanisms of action, which is thought to improve glucose control while posing a low risk of hypoglycemia.
Managing Charcot Foot: An Underdiagnosed Condition in Patients With Diabetes
Because the condition is so challenging to diagnose, particularly in nonpodiatric settings, researchers outlined seven practical clinical pearls that can facilitate diagnosis of Charcot foot.
Study Sheds Light on Type 2 Diabetes Treatment Patterns in US Nursing Homes
A study presented during a poster session at the ADA meeting sought to shed light on this issue by analyzing treatment of type 2 diabetes in US nursing homes using retrospective analysis of prescription claims and Minimum Data Set records from May 2011 to September 2012; records for persons with type 1 diabetes were excluded from the analysis. Read More>>
Gait Speed to Determine Microvascular Disease and Inflammation in Older Diabetes Patients
Research has shown that type 2 diabetes is associated with slower walking, chronic inflammation, and endothelial dysfunction negatively affecting the brain, eye, and kidney. In patients with diabetes, slower walking is linked to impaired cerebral vasoreactivity (CVR); however, the link between walking with central and peripheral vascular disease remains unclear.
In a new study, researchers sought to investigate the association between gait speed, serum soluable vascular and intercellular adhesion molecules (s-VCAM and s-ICAM), CVR, diabetic retinopathy, and urine albumin/creatinine ratio (UACR) in older adults with type 2 diabetes.
Study Examines Barrier to Self-Care
Diabetes management in older adults is complicated by coexisting medical, functional, and psychosocial conditions, which can act as barriers to patients’ ability to perform self-care. New data showed that different barriers impacted patients’ ability to follow diet, exercise, and medication management, according to study results presented at the American Diabetes Association meeting during a poster session titled Age-Related Barriers Impact Self-Care in Community-Living Older Adults with Diabetes.
