A Unique Human Amniotic Wound Allograft Dressing in Healing Recalcitrant Wounds

Case series utilizing a unique cryopreserved human Amniotic Membrane wound dressing consisting of human umbilical cord and amniotic membrane, indicated for use as a wound covering for dermal ulcers and defects. Product applied to 3 chronic non healing wounds resulting in wound closure within 1 to 3 applications.

Introduction: The goal of this case series is to evaluate the wound allograft technology in facilitating removal of necrotic tissue, manage bioburden, and improve healing times in three chronic wounds at an outpatient wound center. The Amniotic Membrane (AM) is the inner layer of the placenta that surrounds the baby during pregnancy. The Amniotic Membrane is the only tissue designed by nature specifically as a universal transplant, protecting the baby and ensuring acceptance by the mother’s immune system. As a result of its unique biochemistry, cryopreserved Amniotic Membrane has been shown to guide regenerative healing while reducing inflammation, adhesion, and scarring.

Method: This case study discusses three patients with chronic non healing wounds at a local wound center. Patients were selected based on chronic wounds over 30 days that were not responding to other treatments. A stage 3 heel pressure injury, venous stasis ulcer and a non-healing diabetic surgical wound on a below the knee amputation. Three patients selected to trial the new allograft. Over the period of 3 months patients were monitored for wound healing at weekly and or biweekly appointments.

Results: All wounds healed with the use of the Amniotic membrane, proving to be easy to use, cost effective and resulting in healing within 1 to 3 applications.

Conclusion: Amniotic membrane wound allograft dressings were clinically effective in healing three chronic non healing wounds with one to three applications.