Wound Healing

The Antibacterial Activity of a Novel Biomaterial Against Key Wound Pathogens: Staphylococcus aureus and Pseudomonas aeruginosa

Aim: The colonization of a wound by microorganisms typically occurs as a continuum extending from contamination, to colonization, and infection. The predominant microbial species observed...

Samantha J. Westgate , PhD;

Matthew Williams , MSc;

05/04/2022

Comparison of two compression bandage systems, including a novel Dual Compression System, in a laboratory-based test under controlled conditions.

Introduction: Compression therapy is the standard of care for edema control and lower limb wound healing. The goal of compression therapy is to provide, sustained, therapeutic compression...

Sandra Guzman ;

Susan Jellum , MSN, RN, CWOCN;

Evan Call , MS, CSM-NRM;

08/19/2021

Fish skin grafts* are a cost effective treatment option for diabetic foot ulcers

Standard treatment of chronic diabetic foot ulcers (DFU) is expensive and, for more than half of DFU patients, unsuccessful1. Health care policy decision makers should seek the most effec...

Robert S. Kirsner , MD, PhD;

Christopher Winters , DPM;

David J. Margolis , MD, PhD;

John C. Lantis II, MD, FACS;

08/19/2021

The Combination of Minced Autologous Tissue and Micronized Collagen-Chondroitin-Sulfate Accelerates Skin Wound Healing in a Porcine Model

Background - The growing demand for cell and tissue-based products, rich in growth factors, multiple cell types, and extracellular matrix, stems from their ability to accelerate the wound...

Paul P. Bonvallet ;

Ankur Gandhi , PhD;

Angana Kharge , PhD;

Sunil Saini , PhD;

08/19/2021

Dermal _-catenin is required for SHH driven hair follicle neogenesis.

Hair follicle neogenesis (HFN) occurs in adult skin upon large skin excisions in mice, serving as a rare regenerative model in mammalian wound healing. Nonetheless, wound healing typicall...

Annette Kaminaka ;

Mayumi Ito , PhD;

Chae Ho Lim , PhD;

08/19/2021

In vitro cytotoxicity profile and physicochemical parameters of a hypochlorous acid based wound irrigation solution

Wound irrigation is an essential step to clean the wound bed through cleansing, irrigating, moistening and debriding the wound, which facilitates healing in acute and chronic wound care. ...

Stephen Law , PhD;

Marcus Swann , PhD;

Steven L. Percival , PhD;

Anne-Marie Salisbury , PhD;

Rui Chen , PhD;

08/19/2021

Closure of Stage IV Pressure Injuries with an Autologous Heterogeneous Skin Construct

Objective: Pressure injuries (PIs) are a difficult, costly and growing problem in the US and worldwide. Available treatments have high failure rates and, even when they are successful, wo...

Deana S. Shenaq , MD;

Mark S. Granick , MD;

Diana Burgueno-Vega , MD;

Nikolai Sopko , MD, PhD;

Melodie Blakely , DPT, CWS, MS;

Diane Duncan , MD;

Edward W. Swanson , MD;

08/19/2021

Disposable Negative Pressure Wound Therapy (d-NPWT) for Small-to-Medium Sized Wounds Including Surgical Wounds, Wound Dehiscence, and Diabetic Foot Ulcerations

Purpose: Negative Pressure Wound Therapy (NPWT) is a commonly used modality to treat wounds. NPWT helps promote wound healing by decreasing edema, removal of tissue debris and exudate. Tr...

Robert J. Klein , DPM, FACFAS, CWS;

08/19/2021

Treatment of A Recalcitrant Diabetic Ulcer with A Synthetic Hybrid-Scale Fiber Matrix*

Chronic wounds, including diabetic ulcers, are difficult to treat and often fail to heal with current therapies. A novel, fully synthetic hybrid-scale fiber matrix* may provide a new trea...

James Longobardi ;

08/19/2021

A comparative effectiveness research study of a native Type I collagen matrix plus polyhexamethylene biguanide antimicrobial and a cryopreserved cadaveric skin allograft for use in diabetic foot ulcers – a non-inferiority analysis

OBJECTIVE: Real-world effectiveness was evaluated in a large patient population at 246 US treatment facilities comparing a purified native cross-linked extracellular matrix plus polyhexam...

Kerry T. Thibodeaux , MD;

Michael Leon Sabolinski , MD;

08/19/2021