Polyhexamethylene Biguanide

In this case series, the author evaluated a multimodal approach in patients with wounds that did not respond to conventional therapy. These patients were initially treated with purified native cross-linked extracellular matrix with...

In this case series, the author...

01/08/2021

Wounds

Original Research

Synergistic Effect and Antibiofilm Activity of a Skin and Wound Cleanser

08/01/2020

Nina Bionda , PhD;

Ann Beal Salamone , MA;

Suprena Poleon , BS;

Rebecca Erin McMahon , MBA, PhD;

Peter D'Arpa ;

In this study, 3 of the components in a wound cleanser are tested to determine synergy in eradicating biofilms of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

In this study, 3 of the...

08/01/2020

Wounds

Case Report and Brief Review

Micropore Particle Technology Promotes Wound Healing, Whereas Polyhexamethylene Biguanide Causes Tissue Degeneration: A Case Report

03/12/2020

Jeanette Sams-Dodd ;

Frank Sams-Dodd ;

A 72-year-old woman with a nontraumatic spinal cord injury developed eschar on her lower right back.

A 72-year-old woman with a...

03/12/2020

Wounds

Preliminary Evaluation of a Purified Native Collagen Matrix with Polyhexamethylene Biguanide Reducing Methicillin Resistant Staphylococcus aureus Infections and Altering Cytokine Profile Using a Porcine Deep Dermal Wound Model

Background: There are a variety of wound matrices designed to treat both acute and chronic wounds, and enhance the healing process. However, patients suffering from these wounds often enc...

Alexander Higa , MA;

Gregory S. Schultz , PhD;

Jie Li , MD, PhD;

Joel Gil , BS, MS;

Jose Valdes , RN;

Soo-Jung Seo ;

Michael Solis , MBA;

Stephen C. Davis , BS, MS;

Joel Gordon , MS, RN, NREMT-P;

Hongen Zhang ;

02/09/2019

Clinical Cases

Examining the Use of a Purified Collagen Matrix Plus PHMB Antimicrobial

03/02/2018

Dr. Alisha Oropallo presents her poster, “Examining the Use of a Purified Collagen Matrix Plus Polyhexamethylene Biguanide Antimicrobial in the Management of Chronic Wounds,” which was exhibited as a poster at the 2017 SAWC Fall in Las...

Dr. Alisha...

03/02/2018

Wounds

Case Series

Effect of a New Purified Collagen Matrix With Polyhexamethylene Biguanide on Recalcitrant Wounds of Various Etiologies: A Case Series

02/28/2018

Kari Yarrow ;

Heather Percise ;

Amber White ;

Dimitrios Lintzeris ;

Mary Gurganus ;

Susan Sherrod ;

Karen Vernon ;

Andy Strickland ;

Kathleen Vergin ;

Laura Johnson ;

In order to control biofilm formation, sequester proteolytic enzymes, and provide a biocompatible scaffold to support healing, the investigators utilize a purified collagen matrix containing polyhexamethylene biguanide (PCMP) in a case series...

In order to control biofilm...

02/28/2018

Wounds