Quality improvement

An old Dermatology tool gets a new life in Wound Care.

DermaBlade Shave Biopsy Instrument is a tool invented by and for dermatologists to perform shave biopsies and assist with Mohs surgeries. However, this widely available instrument is an e...

Igor Melnychuk ;

05/26/2022

A How-To Guide to Improving Wound Reconstruction Outcomes Employing a Novel Prehabilitation Protocol

Introduction: Wound reconstruction may be associated with a significant decline in functional capacity. While most procedures are not considered "major", some of these procedures do carry...

Patrick Schwab , BS, MBA;

Kylie R. McMath , MSN, APRN, FNP-C, CWOCN;

Kari Bechert , BS, PT;

05/26/2022

Physical plasma-activated irrigation therapy clears biofilm infection and promotes wound healing

Biofilm infection is common in diabetic foot ulcers and other human disorders and affects some 17 million people in the US alone. Sharp debridement is the standard of care, but biofilm re...

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Anthony Frei , PhD;

05/26/2022

Protease Modulating Properties of Multi-Action Wound Treatment

Introduction: The aim of this study was to assess the capability of a novel Multi-Action Treatment (MAT*) dressing to modulate levels of Matrix Metalloproteinase (MMP-2 and MMP-9) and Neu...

Mengfan Wu , MD, PhD;

Zhen Yu , MD, PhD;

David Farrar , BSc;

Dennis P. Orgill , MD, PhD;

Valentin Huag , MD;

Brian Ng , BA;

Adriana Panayi , MD;

05/26/2022

Don’t Stop Me Now: Investigating the Influence of Novel Antimicrobial EPC-373K on Keratinocyte Migration In-Vitro

Introduction: Public health concerns over antibiotic-resistant pathogens has spurred the development of non-traditional antimicrobials. These non-traditional antimicrobials offer advantag...

David Goldsmith , PhD;

Stephen C. Davis , BS, MS;

Irena Pastar , PhD;

Hadar A. Lev-Tov , MD, MAS, MSc;

Carla J. Spina , PhD;

Joel Gil , BS, MS;

Phillip Frost ;

Michael Solis , MBA;

Aurelie Boulzemat , PhD;

Bela Kelety , PhD;

05/26/2022

A Transparent Sacral Dressing to Mitigate Tissue Strain

Introduction: Pressure injuries form on load bearing surfaces on the buttocks, sacrum, and heals of immobile patients. Silicone-based multilayer dressings are available to aid in protecti...

Allyn Forsyth , PhD;

William Padula , PhD;

Martha R. Kelso , RN, HBOT;

Benjamin Cohen , PhD;

Jonathan Labovitz , DPM;

Thomas J. Chang , DPM;

Daniel J. Gibson , PhD;

David G. Armstrong , DPM, MD, PhD, MSc;

Jeffrey A. Niezgoda , MD, FACHM, MAPWCA, CHWS;

Julie De Jong ;

05/26/2022

Closed Incision Negative Pressure Therapy Management Versus Standard of Care Over Closed Surgical Incisions in the Reduction of Surgical Site Complications: A Systematic Review and Meta-Analysis of Comparative Studies

Introduction: Closed incision negative pressure therapy (ciNPT*) has been utilized to help manage closed incisions across many surgical specalities.1-6 This systematic review and meta-ana...

Jayesh B. Shah , MD, MSc, UHM, ABPM, CWSP, FAPWCA;

Leah P. Griffin , MS;

05/26/2022

Incidence and Impact of Surgical Site Infections on Length of Stay and Cost of Care

Introduction: Surgical site infections (SSIs) are associated with increased morbidity and mortality; however, current incidence rates of SSIs across procedures and their impact on healthc...

Deb Myers , BSBA;

Dinu Pillai , BS;

Javad Zabihi , MS;

Yuefeng Hou , PhD;

05/26/2022

Optimizing the wound bed for application of a skin graft with a novel adaptive self-assembling peptide barrier scaffold and peptide technology

Introduction: Patients with open wounds often require a skin graft for closure. These patients are sometimes not candidates for immediate skin grafting. The wound bed requires optimizatio...

Thomas A. Davenport , MD;

05/26/2022

Systematic review of cellular and tissue products and Indirect treatment comparison between cellular/acellular and amniotic/non-amniotic allografts in the management of diabetic foot ulcers.

Introduction: Our study aimed to compare the efficacy of cell and tissue products (CTP) dressings in the management of diabetic foot ulcers (DFUs) based on published randomized control tr...

Jaideep Banerjee , PhD;

05/26/2022