DPM

Combination Therapy of a Bioresorbable Synthetic Polymer Matrix and an Ovine Collagen Dressing for Treatment of a Recurrent Venous Leg Ulcer: A Case Study

We present a case of a recurrent venous leg ulcer (VLU) that was resistant to compression and many advanced wound products. In this case study, we examine the long-term clinical effects o...

01/28/2021

Augmented Closure of Surgical Wounds Reduces Complications and Limb Loss Following Transmetatarsal Amputation

Transmetatarsal amputation (TMA) is a viable option to avoid major amputation and limb loss in patients with forefoot sepsis, infection, or tissue loss [1,2]. However, TMAs are associated...

01/28/2021

Addressing the 3 C`s of Compression: Continuity, Consistency and Comfort Through the use of a Novel Dual Compression System

Venous ulceration is the most common type of leg ulceration and a significant clinical problem, affecting approximately 1% of the population and 3% of people over 80 years of age in weste...

01/28/2021

A preliminary clinical evaluation using a novel bioengineered wound product to treat lower extremity ulcers

Diabetes mellitus has become a global pandemic, with ~422 million people affected worldwide, including 29 million people in the US [1, 2]. Patients with diabetes have may have up to a 25%...

01/28/2021

A Case of Calcium Pyrophosphate Deposition in Extra Articular Soft Tissue

A 52 year old male presents with a history of TBI, lumbar/cervical disk degeneration, and progressive radiculopathy for the past 2 years. Patient reports, in the last 2 years he has digre...

01/28/2021

Wound Closure Trajectories in Prospective Cohort Study of Lyopreserved Amniotic Membrane

The aims are twofold: to compare cellular viability between cryopreserved and lyopreserved constructs; and evaluate clinical outcomes of the lyopreserved amniotic membrane (LAM).

01/28/2021

Hyperspectral Imaging Assessment of Tissue Oxygen Saturation Levels Following Amniotic Membrane Application

Hyperspectral imaging was employed to assess the tissue oxygen saturation (StO2) levels in wounds during a clinical trial for an amniotic membrane. 40 patients with foot ulcers were enrol...

01/28/2021

Use of a Purified Reconstituted Bilayer Matrix in the Management of Non-Healing Diabetic Foot Ulcers: A Prospective Randomized Controlled Multicenter Clinical Trial

Patients with diabetic foot ulcers (DFUs), in particular when unresponsive to standard wound care, face serious risks of severe complications, including infection and amputation. The mana...

01/28/2021

Soft Tissue Infection and Osteomyelitis Pathogens in Puncture Wound Injuries

To compare soft tissue infection (SSTI) and osteomyelitis (OM) pathogens in patients with and without diabetes and in patients who did and did not wear shoes at the time of puncture injur...

01/28/2021

Quality of Life Improvement in Patients with Chronic Leg Wounds that were Treated with Wound Irrigation Solution* and Wound Gel+ each Containing Polyhexanide (PHMB) and Betaine

Rationale: Improving health-related quality of life (QoL) is important for patients living with chronic wounds. Chronic wounds don’t progress timely through the normal healing process. P...

01/28/2021