Abstracts

Pre-surgical carcinoembryonic antigen as a recurrence biomarker in stage III colon cancer treated with adjuvant chemotherapy in a Latin American center

Background Colorectal cancer represents the third most incident malignant neoplasm in the world and the second in terms of mortality. In Peru, colon cancer is positioned...

06/27/2022

Analysis of risk factors for recurrence of distal bile duct cancer without lymph node metastasis after curative resection: Is adjuvant therapy really required?

Background High risk of recurrence after CR gives the reasonable weight to adjuvant therapy for DBDC. However, when LN metastasis absent, the role of adjuvant chemothera...

06/27/2022

From 2012 to 2018: Seven years' analysis of NETs, the experience of the Mohamed VI University Hospital center in Marrakech

Background Neuroendocrine tumors are a specific tumor entity because of its rarity (they represent 1% of all digestive tumors) and its heterogeneity both clinical and bi...

06/27/2022

Prognostic impact of clinicopathological characteristics on gastrointestinal stromal tumors in a Latin population

Background Of all neoplasms of the gastrointestinal tract, gastrointestinal stromal tumors (GIST) are the least frequent, representing between 1-2% of cases. Historicall...

06/27/2022

Oxidized-LDL promotes colorectal cancer progression and growth of human colonoides

Background Expression levels of the oxidized-LDL receptor LOX-1 have been related to cancer progression in prostatic, gastric, pancreatic, and colorectal cancer (CRC); h...

06/27/2022

Comprehensive geriatric assessment: Complementary tool in patients with neoplasia of the gastrointestinal tract in a Brazilian university hospital

Background The WHO (World Health Organization) defines an elderly person as an individual aged 60 years or over. A multidimensional evaluation has become necessary for t...

06/27/2022

Modulation of the MYC oncogene using programmable epigenetic mRNA therapeutics as a novel therapy for hepatocellular carcinoma

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths worldwide with a significant unmet medical need. MYC over-expression is associated with agg...

06/27/2022

PIK3CA and TP53 gene mutations in patients with metastatic colorectal cancer from Northeast Romania

Background In metastatic colorectal cancer (mCRC) PIK3CA and TP53 genes are biomarkers that are not currently used in daily practice. In the literature, there is little ...

06/27/2022

Real-world assessment of treatment sequencing of patients with advanced pancreatic cancer in a private practice in Rio de Janeiro, Brazil (Americas Oncologia RJ)

Background The first-line treatment in advanced pancreatic cancer (ACP) is well established by phase III studies, with protocols FOLFIRINOX (FF) and gemcitabine/ nab-pac...

06/27/2022

Study of the hedgehog signaling pathway in colorectal cancer: Association with wild type RAS status

Background EGFR antibodies are efficient in the treatment of patients with RAS wild type metastatic colorectal cancer (mCRC). However, 25% of those patients resist to th...

06/27/2022