Andrei Pikalov, MD, PhD

Dasotraline for Treatment of Adults With Binge-Eating Disorder: Effect on Binge-related Obsessions and Compulsions

Background: In a previous study, dasotraline, a long-acting dopamine/norepinephrine reuptake inhibitor, demonstrated efficacy in the treatment of binge-eating disorder (BED). We now repor...

Leslie Citrome , MD;

Robert Goldman , PhD;

Ling Deng , PhD;

Todd Grinnell , BA;

Andrei Pikalov , MD, PhD;

Joyce Tsai , PhD;

11/22/2019

Lurasidone for the Treatment of Major Depressive Disorder With Mixed Features: Results of a 12-week Open-label Extension Study

Objective: To evaluate the efficacy and tolerability of longer-term treatment with lurasidone in patients with major depressive disorder (MDD) with mixed features.

Antony Loebel , MD;

Andrei Pikalov , MD, PhD;

Michael Tocco , PhD;

Stephen Stahl , MD;

Yongcai Mao , PhD;

03/01/2019

Safety and Effectiveness of Long-term Treatment With Lurasidone in Children and Adolescents With Bipolar Depression: Interim Analysis of a 2-year Open-label Extension Study

Objective: To evaluate the long-term safety and efficacy of lurasidone in children and adolescents with bipolar depression. Methods: Patients (10-17 years) with bipolar depression who co...

Antony Loebel , MD;

Robert Goldman , PhD;

Melissa DelBellow , MD;

Andrei Pikalov , MD, PhD;

Ling Deng , PhD;

Michael Tocco , PhD;

03/01/2019

Efficacy of Lurasidone in Child and Adolescent Patients With Bipolar I Depression and Anxiety: A Post-hoc Analysis

Objective: To evaluate the efficacy of lurasidone in treating pediatric patients with bipolar depression who presented with high levels of anxiety.

Antony Loebel , MD;

Robert Goldman , PhD;

Ling Deng , PhD;

Andrei Pikalov , MD, PhD;

Michael Tocco , PhD;

Mark Owens , DO;

03/01/2019

Long-term Efficacy of Lurasidone in Antipsychotic-Naive vs. Antipsychotic-Exposed Adolescents with Schizophrenia: Post-hoc Analysis of a Two Year, Open-label Study

Background: The aim of this post-hoc analysis was to evaluate the long-term efficacy of lurasidone in antipsychotic-naïve adolescents with schizophrenia.

Robert Goldman , PhD;

Christoph U. Correll , MD;

Andrei Pikalov , MD, PhD;

Michael Tocco , PhD;

Jay Hsu , PhD;

10/08/2020

Efficacy and Safety of Lurasidone in Adolescents with Schizophrenia: Analysis of a 2-year, Open-label Extension Study

Objective: To obtain long-term data on the safety and effectiveness of lurasidone in adolescents with schizophrenia Methods: Adolescents (13-17 years) who completed 6 weeks of double-bli...

Andrei Pikalov , MD, PhD;

Michael Tocco , PhD;

Antony Loebel , MD;

Robert Goldman , PhD;

Ling Deng , PhD;

03/01/2019

Long-term Efficacy of Lurasidone in Pediatric Bipolar Depression: Post-hoc Analysis of Response, Remission and Recovery

Background: The aim of this analysis was to evaluate the long-term efficacy of lurasidone in achieving response and remission in children and adolescents with bipolar depression.

Andrei Pikalov , MD, PhD;

Michael Tocco , PhD;

Manpreet Singh , MD, MS;

Edward Schweizer , MD;

10/08/2020

Effect of Lurasidone on Manic Symptoms and Treatment-Emergent Mania in Children and Adolescents with Bipolar Depression

Background: The aim of these analyses was to assess the effect of lurasidone on manic symptoms and treatment-emergent (TE) mania in pediatric patients with bipolar depression.

Michael Tocco , PhD;

Robert Goldman , PhD;

Andrei Pikalov , MD, PhD;

Courtney Zeni , PhD;

10/08/2020

Assessing the Benefit-Risk Ratio of Approved Treatments for Bipolar Depression Using Likelihood to be Helped or Harmed (LHH) Analyses

Background: Four medications are FDA approved for acute bipolar depression: lurasidone (LUR), cariprazine (CAR), quetiapine IR & XR (QUE), and olanzapine-fluoxetine combination (OFC)....

Leslie Citrome , MD;

Robert Goldman , PhD;

Andrei Pikalov , MD, PhD;

Courtney Zeni , PhD;

10/08/2020

Safety and Effectiveness of Lurasidone in Children and Adolescents With Bipolar Depression: Results From a 2-Year Open-label Extension Study

Objective: The aim of the current study was to evaluate the long-term safety and effectiveness of lurasidone in pediatric bipolar depression. Method: Patients 10-17 years with bipolar I ...

Andrei Pikalov , MD, PhD;

Michael Tocco , PhD;

Melissa DelBello , MD;

Robert Goldman , PhD;

Ling Deng , PhD;

11/22/2019