Bhaskar Rege, PhD, BPharm

A Combination of Olanzapine and Samidorphan Has No Clinically Relevant Effect on QT Prolongation Up to Supratherapeutic Doses

Background: ALKS 3831, a combination of olanzapine and samidorphan (OLZ/SAM) in development for schizophrenia, is intended to mitigate olanzapine-associated weight gain. This thorough QT ...

Lisa L. von Moltke , MD, FCPP;

Lei Sun , PhD;

Sergey Yagoda , PhD, MD;

Hongqu Xue , PhD;

Randy Brown , MS;

Narinder Nangia , PhD;

Bhaskar Rege , PhD, BPharm;

Borje Darpo , MD, PhD;

David McDonnell , MD;

11/22/2019

A New Method for Initiating Treatment With the Long-acting Antipsychotic Aripiprazole Lauroxil

BACKGROUND: Significant delay can occur between the first dose of a long-acting injectable (LAI) antipsychotic and achievement of efficacious plasma concentrations, which is usually addre...

Lisa L. von Moltke , MD, FCPP;

Bhaskar Rege , PhD, BPharm;

Peter J. Weiden , MD, PhD;

Jonathan Meyer , MD;

Rakesh Jain , MD, MPH, RD;

Angela Wehr , PhD;

03/01/2019