Introduction: Lemborexant is approved in the US for treating insomnia in adults. We evaluated the evidence-base for lemborexant and suvorexant, both dual orexin receptor antagonists (DORA...
Abstract: Background: Insomnia contributes to cognitive decline, increased fall risk, and nursing home placement in patients with Alzheimer’s disease and related dementias (ADRD).
Obje...
Abstract: Almost half of patients with cancer have trouble sleeping and treatment can exacerbate these problems.
Objectives: This study evaluated healthcare resource utilization (HCRU) a...
Background: To describe lemborexant and daridorexant for insomnia treatment using number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped or harmed (LHH).
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Abstract: Background: While insomnia occurs in half of adults with type 2 diabetes (T2D), its incremental economic impact in this population is unclear.