diabetic foot ulcer

Effectiveness of daily home electrical stimulation as an adjunctive therapy to accelerate wound healing in people with diabetic foot ulcer – A double blinded randomized control trial

Electrical stimulation (E-Stim) may offer a unique treatment option to heal complicated diabetic foot ulcers (DFU). However, there is no randomized controlled trial to examine effectivene...

Michael E. DeBakey ;

Bijan Najafi , PhD;

Brian D. Lepow , DPM;

Michael E. DeBakey ;

01/28/2021

Value-based Healthcare: Using Human Fibroblast-derived Dermal Substitute in the Treatment of Diabetic Foot Ulcers

OBJECTIVES: (1) To explore DFUs and their burden on the patients’ QoL; (2) To evaluate the limitations of standard of care (SOC) for DFU treatment; (3) To discuss the role of Human Fibrob...

Vipul Dev ;

Antonio Montecalvo ;

Quan Pho ;

Aseel Bin Sawad , PharmD;

11/23/2020

Utilization of a Near Infrared Spectroscopy Device and a pH and Temperature Meter to Quantitatively Measure and Analyze the Immune Response to a Novel Autologous Wound Matrix* Used in the Treatment of Chronic Wounds

Abstract Body: Slow healing of chronic wounds is affected by a combination of local, systemic and psychosocial conditions1. The contributing elements affecting the healing process directl...

Leticia Vallejo , RN;

11/23/2020

Wound Bed Tissue Oxygenation Differences across Angiosomes of the Foot

Angiosome concept states that anatomic blocks of tissue are fed by named arteries. In the foot, almost the entire plantar surface is fed by branches of the posterior tibial artery. Planta...

Amanda L. Killeen , DPM;

11/23/2020

Lower Extremity Wounds Treated Using A Synthetic Nanofiber Matrix*

Lower extremity wounds, including diabetic foot ulcers, venous leg ulcers, and surgical wounds, can be difficult to heal and may benefit from the use of an advanced treatment modality. Th...

Melanie Wilson , DNP;

11/23/2020

Effectiveness of Lower Extremity Electrical Stimulation to Improve Skin Perfusion

While few studies suggest the benefit of electrical stimulation (E-Stim) therapy to accelerate wound healing, the underlying mechanism of action is still debated (1-3). In this study, we ...

Michael E. DeBakey ;

Bijan Najafi , PhD;

Michael E. DeBakey ;

Brian D. Lepow , DPM;

Michael E. DeBakey ;

11/23/2020

Use of Bilayer Wound Matrix for Closure of Post-Mohs Surgery Defects of the Nose

There are over 5 million skin cancers reported in the United States annually. Among those, though not followed statistically, Mohs surgical resections for skin cancer on the nose are comm...

Bijan Najafi , PhD;

Miguel Montero ;

11/23/2020

Effectiveness of daily home electrical stimulation as an adjunctive therapy to accelerate wound healing in people with diabetic foot ulcer – A double blinded randomized control trial

Electrical stimulation (E-Stim) may offer a unique treatment option to heal complicated diabetic foot ulcers (DFU) (1-3). However, there is no randomized controlled trial to examine effec...

Brian D. Lepow , DPM;

Michael E. DeBakey ;

Bijan Najafi , PhD;

Michael E. DeBakey ;

11/23/2020

Proof of principle: rapidly removing biofilm and necrosis in hard to heal ulcers using a hygroscopic chemical compound.

Introduction: The chronicity of hard-to-heal lesions is caused and sustained by a number of factors, including the development and presence of biofilm, which contributes significantly to ...

Alberto Cogo ;

Hans Pieter Snels ;

Bert J. Quint ;

Carlo Alberto Bignozzi ;

Gregory S. Schultz , PhD;

Michel H.E. Hermans , MD;

11/23/2020