Umesh K. Arora, MD

Direct Thrombin Inhibitors (Part 2 of 2)

08/01/2008

Clinical Trials of Direct Thrombin Inhibitors The 2 direct thrombin inhibitors that have been studied most extensively are hirudin and bivalirudin. The earlier trials focussed on hirudin in the setting of acute coronary syndromes, MI and PCI...

Clinical Trials of Direct...

08/01/2008

Journal of Invasive Cardiology

Direct Thrombin Inhibitors (Part 1 of 2)

08/01/2008

Umesh K. Arora , MD;

Meeney Dhir , MD;

Thrombin plays a central role in clot formation through platelet activation and fibrin generation at the sites of arterial disruption, such as that caused by angioplasty or plaque rupture.1–3 Thrombin also amplifies its own generation by...

Thrombin plays a central role in...

08/01/2008

Journal of Invasive Cardiology

Case Report

Successful Multi-vessel Percutaneous Coronary Intervention
with Bivalirudin In A Patient With Severe Hemophilia A:
A Case Rep

08/01/2008

Umesh K. Arora , MD;

Meeney Dhir , MD;

Guillermo Cintron , MD;

Joel A. Strom , MD;

ABSTRACT: We describe a 64-year-old male with severe hemophilia A (factor VIII-dependent), acute myocardial infarction (MI) and congestive heart failure (CHF) who underwent successful multi-vessel percutaneous coronary intervention (PCI). The...

ABSTRACT: We describe a...

08/01/2008

Journal of Invasive Cardiology

Clinical Images

Severe Left Main Coronary Artery Spasm?

08/01/2008

Umesh K. Arora , MD;

Meeney Dhir , MD;

Case History. A 59-year-old man with a history of percutaneous coronary intervention of the right coronary artery (RCA) was admitted with unstable angina. An electrocardiogram revealed T-wave inversions and non specific ST changes in leads...

Case History. A 59-year-old man...

08/01/2008

Journal of Invasive Cardiology

Review

Rescue Percutaneous Coronary Intervention: A Review

08/01/2008

Umesh K. Arora , MD;

Meeney Dhir , MD;

The primary goal of therapy for acute myocardial infarction (AMI) is rapid, complete and sustained restoration of infarct-related artery (IRA) blood flow and myocardial perfusion, with a consequent positive impact on the patient’s outcome....

The primary goal of therapy for...

08/01/2008

Journal of Invasive Cardiology

Original Contribution

Strategies to Optimize Percutaneous Coronary Intervention Outcomes in Diabetics

09/05/2008

Umesh K. Arora , MD;

Coronary artery disease (CAD) is the most frequent cardiovascular complication of diabetes. It occurs 2–3 times more often in patients with diabetes than in those without diabetes.

Coronary artery disease (CAD) is...

09/05/2008

Vascular Disease Management