Background: Many real-world databases do not capture the Patient Health Questionnaire-9 (PHQ-9), a self-reported questionnaire used to measure depression severity. We created a model to p...
Introduction: Although major depressive disorder (MDD) is the leading cause of disability worldwide, the relationship between depression severity and risk of ER visit/hospitalization is u...
Introduction: Major depressive disorder (MDD) and suicidal ideation/behavior, both incur substantial mental health resource utilization (MHRU) burden, yet little is known of the burden of...
Background: Among patients with major depressive disorder (MDD), those with treatment-resistant depression (TRD) have a higher economic burden. However, healthcare resource utilization (H...
BACKGROUND: Comorbidities complicate clinicians' efforts to manage major depressive disorder (MDD). Pre-existing conditions and drug-drug interactions (DDI) may limit the array of safe ph...
Background: Esketamine nasal spray (ESK) plus comprehensive standard of care (SOC) vs placebo plus SOC was studied in two phase 3 antidepressant clinical trials among a sub-population of ...
Introduction: Although depression is a known risk factor for suicide, little is known about how the prevalence of co-occurring major depressive disorder (MDD) and suicidal ideation/behavi...