Monique Y. Rennie, PhD

Innovations in Research Methods and Reporting

Wound Assessments to Measure Endpoints: An Update From the Wound Care Collaborative Community (WCCC)

09/08/2023

The Wound Care Collaborative Community is preparing to present the FDA with evidence to include parameters such as percent area reduction and percent volume reduction as acceptable primary endpoints in studies for the treatment of wounds.

The Wound Care Collaborative...

09/08/2023

Wounds

Improved Detection of Infection Using Bacterial Fluorescence Imaging Reveals the True Proportion of Infected Wounds in Long Term Care Facilities

10-54% of long term care (LTC) facility patients have a chronic wound1. Often, infections develop in these wounds due to delays in detection of high bacterial loads. Delays are attributed...

Monique Y. Rennie , PhD;

Ashley Jacob ;

Anna D'Souza ;

01/28/2021

Addressing Pressure Ulcer Bacteria: Impact of Fluorescence Imaging on Assessment & Treatment

Pressure ulcers (PUs) occur in up to 15% of inpatients1 and 37-53% of long-term care (LTC) residents2 and are plagued by infection. Many clinical signs and symptoms of infection (CSS) in ...

Liis Teene , MSc;

Thomas E. Serena , MD, FACS, FACHM, MAPWCA;

Monique Y. Rennie , PhD;

Anna Desouza , PhD;

01/28/2021

Real-world Evidence Demonstrating Utility of Bacterial Fluorescence Imaging to Guide Treatment Decision Making in 135 Wounds

Abstract Body: Introduction: Evaluation of clinical signs and symptoms of infection is the current standard of care (SoC) for assessing bacterial colonization in wounds and is used to inf...

Anna D'Souza ;

Monique Y. Rennie , PhD;

Nathan Krehbiel ;

Alyssa Mackey ;

11/23/2020

In vivo Detection of Bacteria Within a Biofilm Using a Point-of-care Fluorescence Imaging Device

Abstract Body: Introduction: Biofilm is bacteria that exists within a protective matrix, making it particularly challenging to eradicate through antimicrobial and antibiotic strategies. B...

Monique Y. Rennie , PhD;

Landrye Reynolds ;

Isaiah George ;

Laura M. Jones , PhD;

Allie C. Smith ;

Rachel Diaz ;

Andrea J. Lopez ;

William C. Little , MD;

11/23/2020

Addressing Pressure Ulcer Bacteria: Impact of Fluorescence Imaging on Assessment and Treatment

Pressure ulcers (PUs) occur in up to 15% of inpatients1 and 37-53% of long-term care (LTC) residents2 and are plagued by infection. Many clinical signs and symptoms of infection (CSS) in ...

Liis Teene , MSc;

Anna Desouza , PhD;

Thomas E. Serena , MD, FACS, FACHM, MAPWCA;

Monique Y. Rennie , PhD;

11/23/2020

Health Economics of Bacterial Fluorescence Imaging: Realized Cost Savings with Fluorescence Informed Sampling of Chronic Wounds

Introduction: More than $33 billion is spent annually on chronic wounds in the United States, leaving facilities and payers in search of key areas for cost reduction.

Liis Teene , MSc;

Monique Y. Rennie , PhD;

12/02/2019

Levine Technique Is Inadequate for Bacterial Recovery in the Sampling of Wounds

Introduction: Levine technique is the current gold standard for swab-based wound sampling. Punch biopsies more accurately sample subsurface tissues, but many clinicians prefer Levine to a...

Laura M. Jones , PhD;

Kim Tapang ;

Ron Linden ;

Liis Teene , MSc;

Monique Y. Rennie , PhD;

Stephanie Fedorov ;

08/19/2019

Bacterial Fluorescence Image Guidance of Antimicrobial Decision Making and Stewardship

Objective: Targeted, appropriate antimicrobials can prevent escalation to infection and future antibiotic necessity. Antimicrobial misuse often stems from diagnostic uncertainty duri...

Khristina Serena ;

Matthew Sabo , DPM;

Gabriel Halperin ;

Thomas E. Serena , MD, FACS, FACHM, MAPWCA;

Monique Y. Rennie , PhD;

Lam Le , MD;

Keyur Patel ;

Raphael Yaakov ;

08/19/2019

Real-time Bacterial Fluorescence Imaging Improves the Accuracy of Wound Assessment in Detecting Moderate-to-heavy Bacterial Load That Are Not Otherwise Clinically Evident

Objective: The clinical evaluation of signs and symptoms (CSS) to determine a wound’s bacterial load and infection status is paramount to wound assessment.

Laura Serena ;

Khristina Serena ;

Thomas E. Serena , MD, FACS, FACHM, MAPWCA;

Monique Y. Rennie , PhD;

Raphael Yaakov ;

08/19/2019