precision medicine

Research Reports

Clinical and Economic Impact of Implementing HealthPathways at a Musculoskeletal Radiology Department

12/13/2023

Simon R. Davies, MBBCh, MD

Kathleen Lyons, MBBCh

Kausik Mukherjee, MBBS

Ramakrishna Kishore, MBBS

Khurram Hashmi, MBBCh

Maria Dyban, LLM

Anna Kuczynska, MBBCh

Simon R. Davies, MBBCh, and colleagues investigate the impact of HealthPathways on management and primary care clinicians in a musculoskeletal radiology department.

Simon R. Davies, MBBCh, and...

12/13/2023

Journal of Clinical Pathways

Research Reports

Off-Label Use of Precision Oncology Therapeutics in Advanced Solid Cancers Following Identification of Associated Variants via Multicancer Next-Generation Sequencing Panel: A Real-World Evidence Pilot Study

09/19/2023

Julie Wiedower, PhDc

Nicole Zhang, MPH

Rebecca Nagy, MS

Kathryn Lang, MD

Jayati Saha, PhD, MPH

Julie Wiedower, PhDc, and colleagues analyze the frequency of real-world off-label therapy utilization post–comprehensive genomic profiling via liquid biopsy in precision oncology.

Julie Wiedower, PhDc, and...

09/19/2023

Journal of Clinical Pathways

OCPC: IN SESSION

Artificial Intelligence in Oncology: The Wins, The Challenges, and How We Can Deliver on Personalized Cancer Care

09/19/2023

Matthew Biancalana, PhD

Tushar Pandey, MBA

Mathew Biancalana, PhD, and Tushar Pandey, MBA, discuss how artificial intelligence can enhance the field of precision medicine and help unburden physicians from laborious and repetitive tasks in diagnostic analyses.

Mathew Biancalana, PhD, and...

09/19/2023

Journal of Clinical Pathways

Review

NGS Testing in Non–Small Cell Lung Cancer

09/19/2023

Winston Wong, PharmD

Gordon Kuntz

Winston Wong, PharmD, and Gordon Kuntz provide an update on the current status of the research and barriers for using next-generation sequencing in NSCLC and summarize the discussion and next steps that the NGS Institute’s NSCLC Subcommittee...

Winston Wong, PharmD, and Gordon...

09/19/2023

Journal of Clinical Pathways

News

Real-World Outcomes of Companion Diagnostic Testing in Advanced NSCLC

07/09/2020

A new study published in The Oncologist (online July 6, 2020; doi:10.1634/theoncologist.2019-0864) demonstrated the clinical utility of companion diagnostic testing as a first step in treating non-squamous advanced...

A new...

07/09/2020

Journal of Clinical Pathways

News

Impact of NGS on Treatment Selection in AML

06/08/2020

Next-generation sequencing (NGS) has the potential to directly impact treatment decisions and outcomes in patients with acute myeloid leukemia (AML), according to a study presented at the American Society of Clinical...

...

06/08/2020

Journal of Clinical Pathways

Research in Review

Novel Prostate Cancer Biomarkers May Improve Targeted Therapy

08/15/2017

JCP Editors

Recent research has uncovered a new cause of treatment resistance in prostate cancer, which may improve targeted therapy efforts. Mutations within the SPOP gene are the most frequently documented genetic changes in...

Recent...

08/15/2017

Journal of Clinical Pathways

Interview

Clinical Pathways and Value-Based Care at the Dana Farber Cancer Institute

08/03/2017

JCP Editors

Journal of Clinical Pathways spoke with Aymen Elfiky, MD, MPH, MSc, attending physician, clinical oncology, Dana Farber Cancer Institute (Boston, MA), about clinical pathway implementation at the Institute,...

...

08/03/2017

Journal of Clinical Pathways

Research in Review

CAR T-Cells Improve Outcomes in Multiple Myeloma

06/13/2017

JCP Editors

Multiple studies have demonstrated positive results for chimeric antigen receptor (CAR) T-cells in treating relapsed and refractory multiple myeloma, according to presentations at the 2017 ASCO Annual Meeting (June...

...

06/13/2017

Journal of Clinical Pathways

Research in Review

Prostate Cancer Testing Guidelines Omit Critical Genetic Features

06/13/2017

JCP Editors

Current National Comprehensive Cancer Network (NCCN) guidelines and Gleason scores cannot reliably stratify patients with risk of prostate cancer for the presence or absence of pathogenic germline variants,...

...

06/13/2017

Journal of Clinical Pathways