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Treatment of Pediatric Burns with Concentrated Surfactant Gel Technology (CST) with or Without an Antimicrobial Agent
OBJECTIVE: A concentrated surfactant gel technology (CST) gel was designed to aid in maintaining moist wound healing and to soften debris, assisting in surfactant driven autolytic debridement. A clinical study was conducted to look at its effect on several outcomes.
MATERIALS AND METHODS: Burns were treated with CST or a combination of CST with a topical antimicrobial cream (AB) (CSTA: CST gel applied over the wound, AB on the cover dressing).
RESULTS: As part of a larger clinical trial, 15 children (median age, 5.0 years; 9 girls) with burns were treated with CST (n = 7) or CSTA (n = 8). The median study burn size was 2.7% and 1.0% total body surface area, respectively. Scalds were the most frequent type of burn, followed by contact burn. Thorax, back, and lower leg were the most common anatomical locations. The CST group had a larger percentage of deep-partial, (small) full-thickness, and mixed-partial (small) full-thickness burns than the CSTA group (57% vs. 33%, respectively). In all but 1 patient, no specific debridement was deemed necessary. Average time to reepithelialization was 13.5 days for CST and 10.5 days for CSTA, with 1 outlier (50 days) in the CSTA group (included in the calculation). Ease of application of CST was judged to be good in all patients. No infections or other adverse experiences occurred in either group.
CONCLUSIONS: Pediatric patients were treated with a surfactant or a combination of a surfactant and a topical antimicrobial. Time to reepithelialization was short with both therapies: patients in the CST group took 3 more days on average but this may be due to the larger percentage of deep burns in this group. Although the numbers in this pilot trial were small, it seems to indicate that CSTA, with or without and antibiotic, is a safe and effective way to treat smaller pediatric burns.
CITATION
Pittenger T, Curran D, Hermans MH. Treatment of pediatric burns with concentrated surfactant gel technology (CST) with or without an antimicrobial agent. Poster presented at: Symposium on Advanced Wound Care Fall; November 2-4, 2018; Las Vegas, NV.
Product: Plurogel (Medline Industries, Northfield, IL)
This abstract was not subject to the WOUNDS peer-review process.
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