Skip to main content

Advertisement

ADVERTISEMENT

Original Contribution

Non-ST Elevation Myocardial Infarction With Occluded Culprit Artery: A Continuum of Mortality Risk Across the Spectrum of Acute Myocardial Infarction

Luís Graça-Santos, MD1;  Catarina Ruivo, MD1;  Fernando Montenegro-Sá, MD1;  Rita Carvalho, MD1;  Sara Fernandes, MD1;  Fátima Saraiva, MD1; Joana Correia, MD1;  Sidarth Pernencar, MD1;  Francisco Soares, MD1; Adriana Belo2;  João Morais, MD, PhD1; on behalf of the Portuguese National Registry of Acute Coronary Syndromes (proACS)2

December 2021
1557-2501
J INVASIVE CARDIOL 2021;33(12):E931-E938. Epub 2021 November 3. doi:10.25270/jic/20.00724

1. Collet JP, Thiele H, Barbato E, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2021;42:1289-1367.

2. Khan AR, Golwala H, Tripathi A, et al. Impact of total occlusion of culprit artery in acute non-ST elevation myocardial infarction: a systematic review and meta-analysis. Eur Heart J. 2017;38:3082-3089.

3. Karwowski J, Gierlotka M, Gąsior M, et al. Relationship between infarct artery location, acute total coronary occlusion, and mortality in STEMI and NSTEMI patients. Pol Arch Intern Med. 2017;127:401-411.

4. Wang TY, Zhang M, Fu Y, et al. Incidence, distribution, and prognostic impact of occluded culprit arteries among patients with non–ST-elevation acute coronary syndromes undergoing diagnostic angiography. Am Heart J. 2009;157:716-723.

5. Kim MC, Ahn Y, Rhew SH, et al. Impact of total occlusion of an infarct-related artery on long-term mortality in acute non-ST-elevation myocardial infarction patients who underwent early percutaneous coronary intervention. Int Heart J. 2012;53:160-164.

6. Montalescot G, Dallongeville J, Van Belle E, et al. STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Eur Heart J. 2006;28:1409-1417.

7. Menon V, Ruzyllo W, Carvalho AC, et al. Infarct artery distribution and clinical outcomes in occluded artery trial subjects presenting with non–ST-segment elevation myocardial infarction (from the long-term follow-up of occluded artery trial [OAT]). Am J Cardiol. 2013;111:930-935.

8. Rasoul S, de Boer MJ, Suryapranata H, et al. Circumflex artery-related acute myocardial infarction: limited ECG abnormalities but poor outcome. Neth Heart J. 2007;15:286-290.

9. Timóteo AT, Mimoso J. Registo Nacional de Síndromes Coronárias Agudas: 15 anos de um registo prospetivo contínuo. Rev Port Cardiol. 2018;37:563-573.

10. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40:237-269.

11. Ponikowski P, Voors AA, Anker SD, et al. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016;37:2129-2200.

12. Weber C, Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med. 2011;17:1410-1422.

13. Lloyd-Jones DM, Morris PB, Ballantyne CM, et al. 2017 focused update of the 2016 ACC expert consensus decision pathway on the role of non-statin therapies for LDL-cholesterol lowering in the management of atherosclerotic cardiovascular disease risk. J Am Coll Cardiol. 2017;70:1785-1822.

14. Bentzon JF, Otsuka F, Virmani R, Falk E. Mechanisms of plaque formation and rupture. Circ Res. 2014;114:1852-1866.

15. McManus DD, Gore J, Yarzebski J, et al. Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI. Am J Med. 2011;124:40-47.

16. Polonski L, Gasior M, Gierlotka M, et al. A comparison of ST elevation versus non-ST elevation myocardial infarction outcomes in a large registry database. Int J Cardiol. 2011;152:70-77.

17. Bahrmann P, Rach J, Desch S, et al. Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy. Clin Res Cardiol. 2011;100:457-467.

18. Warren J, Mehran R, Yu J, et al. Incidence and impact of totally occluded culprit coronary arteries in patients presenting with non-ST segment elevation myocardial infarction. Am J Cardiol. 2015;115:428-433.

19. Ibanez B, James S, Agewall S, et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2017;39:119-177.

20. Hung CS, Chen YH, Huang CC, et al. Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded “culprit” artery — a systemic review and meta-analysis. Crit Care. 2018;22:34.

21. From AM, Best PJM, Lennon RJ, et al. Acute myocardial infarction due to left circumflex artery occlusion and significance of ST-segment elevation. Am J Cardiol. 2010;106:1081-1085.

22. Stribling WK, Kontos MC, Abbate A, et al. Left circumflex occlusion in acute myocardial infarction (from the National Cardiovascular Data Registry). Am J Cardiol.  2011;108:959-963.

23. Daly MJ, Scott PJ, Harbinson MT, Adgey JA. Improving the diagnosis of culprit left circumflex occlusion with acute myocardial infarction in patients with a nondiagnostic 12‐lead ECG at presentation: a retrospective cohort study. J Am Heart Assoc. 2019;8;e011029.

24. Miyachi H, Takagi A, Miyauchi K, et al. Current characteristics and management of ST elevation and non-ST elevation myocardial infarction in the Tokyo metropolitan area: from the Tokyo CCU network registered cohort. Heart Vessels. 2016;31:1740-1751.

25. Neumann JT, Goßling A, Sörensen NA, et al. Temporal trends in incidence and outcome of acute coronary syndrome. Clin Res Cardiol. 2020;109:1186-1192.

26. Borrayo-Sánchez G, Rosas-Peralta M, Ramírez-Arias E, et al. STEMI and NSTEMI: real-world study in Mexico (RENASCA). Arch Med Res. 2018;49:609-619.

27. Dixon WC, Wang TY, Dai D. Anatomic distribution of the dulprit lesion in patients with non–ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention. J Am Coll Cardiol. 2008;52:1347-1348.

28. Brezinov OP, Klempfner R, Zekry SB, et al. Prognostic value of ejection fraction in patients admitted with acute coronary syndrome: a real world study. Medicine (Baltimore). 2017;96:e6226.

29. Stribling WK, Kontos MC, Abbate A, et al. Clinical outcomes in patients with acute left circumflex/obtuse marginal occlusion presenting with myocardial infarction. J Interv Cardiol. 2011;24:27-33.

30. Pelliccia F, Pasceri V, Niccoli G, et al. Predictors of mortality in myocardial infarction and nonobstructed coronary arteries: a systematic review and meta-regression. Am J Med. 2020;133:73-83.e4.

31. Sá FM, Ruivo C, Santos LG, et al. Myocardial infarction with nonobstructive coronary arteries: a single-center retrospective study. Coron Artery Dis. 2018;29:511-515.

32. Belle L, Cayla G, Cottin Y, et al. French registry on acute ST-elevation and non-ST-elevation myocardial infarction 2015 (FAST-MI 2015). Design and baseline data. Arch Cardiovasc Dis. 2017;110:366-378.


Advertisement

Advertisement

Advertisement