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Volume 31 - Issue 4 - April, 2019

April 2019 Table of Contents
02/03/2022
Coronary Artery Disease Procedural Impact of a Kissing-Balloon Predilation (Pre-Kissing) Technique in Patients With Complex Bifurcations Undergoing Drug-Eluting Stenting Francesco Burzotta, MD, PhD*; Osama Shoeib, MD, PhD*; Cristina...
Coronary Artery Disease Procedural Impact of a Kissing-Balloon Predilation (Pre-Kissing) Technique in Patients With Complex Bifurcations Undergoing Drug-Eluting Stenting Francesco Burzotta, MD, PhD*; Osama Shoeib, MD, PhD*; Cristina...
Coronary Artery...
02/03/2022
Journal of Invasive Cardiology
Procedural Impact of a Kissing-Balloon Predilation (Pre-Kissing) Technique in Patients With Complex Bifurcations Undergoing Drug-Eluting Stenting
03/28/2019
Giampaolo Niccoli, MD, PhD; Carlo Trani, MD; Lorenzo Genuardi, MD; Francesco Burzotta, MD, PhD; Antonio Maria Leone, MD, PhD; Cristina Aurigemma, MD, PhD; Italo Porto, MD, PhD; Filippo Crea, MD
This study was designed to help assess the impact of lesion predilation with kissing inflation using under-sized balloons (pre-kissing) on the procedural outcome of percutaneous coronary intervention (PCI) on complex bifurcation lesions...
This study was designed to help assess the impact of lesion predilation with kissing inflation using under-sized balloons (pre-kissing) on the procedural outcome of percutaneous coronary intervention (PCI) on complex bifurcation lesions...
This study was designed to help...
03/28/2019
Journal of Invasive Cardiology
Reverse Cardiac Remodeling After Transcatheter Treatment of Severe Tricuspid Regurgitation Using the Edge-to-Edge MitraClip Technique
03/28/2019
Karl-Ludwig Laugwitz, MD; Jakob Ledwoch, MD; Carmen Fellner; Felix Poch; Leonhard Schlatterbeck; Michael Dommasch, MD; Ralf Dirschinger, MD; Anja Stundl, MD; Christian Kupatt, MD; Petra Hoppmann, MD
In recent years, transcatheter treatment techniques for tricuspid regurgitation have rapidly evolved. Cardiac remodeling analysis beyond clinical outcome assessment following transcatheter tricuspid repair is still lacking. The aim of the...
In recent years, transcatheter treatment techniques for tricuspid regurgitation have rapidly evolved. Cardiac remodeling analysis beyond clinical outcome assessment following transcatheter tricuspid repair is still lacking. The aim of the...
In recent years, transcatheter...
03/28/2019
Journal of Invasive Cardiology
Paclitaxel Drug-Coated Balloon After Bare-Metal Stent Implantation, an Alternative Treatment to Drug-Eluting Stent in High Bleeding Risk Patients (The Panelux Trial)
03/28/2019
Christophe Piot, MD; Jerome Roncalli, MD, PhD; Matthieu Godin, MD; Kamel Boughalem, MD; John Shayne, MD; Bruno Huret, MD; Loic Belle, MD; Max Amor, MD; Benjamin Faurie, MD, PhD; Bernard Karsenty, MD; Florence Leclercq, MD, PhD; Guillaume Cayla, MD, PhD
Prolonged dual-antiplatelet therapy in high bleeding risk (HBR) patients undergoing percutaneous coronary intervention can be challenging. We assessed the clinical safety of bare-metal stent implantation followed by drug-coated balloon...
Prolonged dual-antiplatelet therapy in high bleeding risk (HBR) patients undergoing percutaneous coronary intervention can be challenging. We assessed the clinical safety of bare-metal stent implantation followed by drug-coated balloon...
Prolonged dual-antiplatelet...
03/28/2019
Journal of Invasive Cardiology
A Percutaneous Crossing Algorithm for Femoropopliteal and Tibial Artery Chronic Total Occlusions (PCTO Algorithm)
03/28/2019
Mohammad M. Ansari, MD; Jihad A. Mustapha, MD, FACC, FSCAI; Emmanouil S. Brilakis, MD, PhD, FACC, FAHA, FESC, FSCAI; Subhash Banerjee, MD, FSCAI; Bryan T. Fisher, Sr., MD; Constantino S. Peña, MD, FAHA, FSCCT, FSIR; Arthur C. Lee, MD, FACC, FSCAI; John H. Rundback, MD, FAHA, FSIR; Mehdi H. Shishehbor, DO, MPH, PhD; Ehrin J. Armstrong, MD, MSc, FACC; Sahil A. Parikh, MD, FACC, FSCAI
This review outlines a contemporary ultrasound-based approach to crossing femoropopliteal PCTOs based on a review of prospectively collected case report surveys, published evidence, and expert opinion compiled by the writing group members.
This review outlines a contemporary ultrasound-based approach to crossing femoropopliteal PCTOs based on a review of prospectively collected case report surveys, published evidence, and expert opinion compiled by the writing group members.
This review outlines a...
03/28/2019
Journal of Invasive Cardiology
Prolonged Ultrasound-Assisted Catheter-Directed Low-Dose Thrombolysis for Acute Pulmonary Embolism Unresponsive to Systemic Thrombolysis
03/27/2019
Francesco De Cobelli, MD; Francesco Gentile, MD; Alberto Margonato, MD; Francesco Giannini, MD; Azeem Latib, MD, BCh, MBBCh; Alessandro Beneduce, MD; Gianmarco Iannopollo, MD; Antonio Colombo, MD; Letizia Bertoldi, MD; Francesco Melillo, MD; Marta Panzeri, MD; Roberto Nicoletti, MD
Our experience suggests that ultrasound-assisted thrombolysis with the EkoSonic system could be a valid bail-out strategy in cases of massive pulmonary embolism unresponsive to systemic thrombolysis and provides insight into the role of...
Our experience suggests that ultrasound-assisted thrombolysis with the EkoSonic system could be a valid bail-out strategy in cases of massive pulmonary embolism unresponsive to systemic thrombolysis and provides insight into the role of...
Our experience suggests that...
03/27/2019
Journal of Invasive Cardiology
Dissection Re-entry Technique: How is it Really Looking?
03/27/2019
Konstantina Katsanou, MD; Athanasios Antonakopoulos, MD, MSc; Ioannis Tsiafoutis, MD; Dimitrios Protogeros, MD; Michalis Koutouzis, MD, PhD; Theodoros Zografos, MD, PhD
Dissection re-entry is a widely used technique in many chronic total occlusion centers. This account of a failed re-entry attempt provides in vivo photographic evidence of how the vessel looked after such an attempt. Operators are advised to...
Dissection re-entry is a widely used technique in many chronic total occlusion centers. This account of a failed re-entry attempt provides in vivo photographic evidence of how the vessel looked after such an attempt. Operators are advised to...
Dissection re-entry is a widely...
03/27/2019
Journal of Invasive Cardiology
The Impact of Plaque Rupture on Mismatch Between Intravascular Ultrasound Minimal Lumen Area and Fractional Flow Reserve Measured in an Angiographically Borderline Left Main With Complex Left Anterior Descending Involvement
03/27/2019
Gary S. Mintz, MD; Lukasz Kalinczuk, MD, PhD; Michal Swierczewski; Zuzanna Sala; Michal Gwidon Markiewicz, MD
Plaque rupture is known to affect the mismatch between anatomy and physiology. In this case, we relied on fractional flow reserve along with the tomographic perspective of intravascular ultrasound.
Plaque rupture is known to affect the mismatch between anatomy and physiology. In this case, we relied on fractional flow reserve along with the tomographic perspective of intravascular ultrasound.
Plaque rupture is known to...
03/27/2019
Journal of Invasive Cardiology
Cocaine-Associated ST-Elevation Myocardial Infarction: Different Pathophysiological Mechanisms
03/27/2019
Alfonso Jurado-Román, MD, PhD; José Abellán-Huerta, MD, PhD; María T. López-Lluva, MD; Ignacio Sánchez-Pérez, MD; Fernando Lozano Ruíz-Poveda, MD, PhD
There are many underlying mechanisms for cocaine-associated myocardial infarction, and the culprit must be elucidated for appropriate therapeutic management. Optical coherence tomography provides unique insights when angiography alone has...
There are many underlying mechanisms for cocaine-associated myocardial infarction, and the culprit must be elucidated for appropriate therapeutic management. Optical coherence tomography provides unique insights when angiography alone has...
There are many underlying...
03/27/2019
Journal of Invasive Cardiology
Percutaneous Closure of an Iatrogenic Perimembranous Ventricular Septal Defect After Mechanical Aortic Valve Replacement Using a Novel Venous-Arteriovenous Loop
03/27/2019
Gary Shing-Him Cheung, MBBS; Yat-Yin Lam, MD; Chak-Yu So, MBChB
This image illustrates the feasibility of percutaneous closure of perimembranous ventricular septal defect occluder in a patient with mechanical aortic valve replacement utilizing a novel venous-arteriovenous loop, and emphasizes the...
This image illustrates the feasibility of percutaneous closure of perimembranous ventricular septal defect occluder in a patient with mechanical aortic valve replacement utilizing a novel venous-arteriovenous loop, and emphasizes the...
This image illustrates the...
03/27/2019
Journal of Invasive Cardiology

News

Intravascular Imaging
ECLIPSE Trial: Intravascular Imaging Can Improve Outcomes for Complex Stenting Procedures in Patients with High-Risk Calcified CAD
03/31/2025
“The ECLIPSE trial shows that use of intravascular imaging (IVI) to guide coronary stenting in severely calcified lesions prevents death, stent thrombosis, and unplanned repeat procedures in this high-risk patient population,” says first...
“The ECLIPSE trial shows that use of intravascular imaging (IVI) to guide coronary stenting in severely calcified lesions prevents death, stent thrombosis, and unplanned repeat procedures in this high-risk patient population,” says first...
“The ECLIPSE trial shows that...
03/31/2025
Cath Lab Digest
Aortic Stenosis
New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients
03/31/2025
New data from DETECT AS and the EARLY TAVR Trial were presented at ACC.25 in Chicago, addressing the critical needs of patients with structural heart disease.
New data from DETECT AS and the EARLY TAVR Trial were presented at ACC.25 in Chicago, addressing the critical needs of patients with structural heart disease.
New data from DETECT AS and the...
03/31/2025
Cath Lab Digest
CAD in Women
New Intermountain Health Study Finds Gap Between Heart Disease Outcomes in Men and Women Has Narrowed Over Past 20 Years  
03/31/2025
Women studied tended to be older with more comorbidities (like high blood pressure, diabetes, and history of stroke and heart failure), have more stable chest pain, and experience less severe chest pain or heart attack when they came into the...
Women studied tended to be older with more comorbidities (like high blood pressure, diabetes, and history of stroke and heart failure), have more stable chest pain, and experience less severe chest pain or heart attack when they came into the...
Women studied tended to be older...
03/31/2025
Cath Lab Digest
AI
HeartFocus Clinical Trial Proves AI Can Empower Novices to Deliver Diagnostic-Quality Cardiac Ultrasounds
03/31/2025
Results showed that 100% of exams conducted by novices using HeartFocus met the diagnostic standards for all primary endpoints, with a strong correlation to expert-acquired scans across qualitative and quantitative assessments.
Results showed that 100% of exams conducted by novices using HeartFocus met the diagnostic standards for all primary endpoints, with a strong correlation to expert-acquired scans across qualitative and quantitative assessments.
Results showed that 100% of...
03/31/2025
Cath Lab Digest
plaque analysis
CONFIRM2 Registry: Late-Breaking Clinical Trial Results Demonstrate the Predictive Power of Cleerly's AI-QCT for Women’s Cardiovascular Risk at ACC.25
03/31/2025
The findings demonstrate that AI-QCT features of coronary artery disease (CAD), as detected by Cleerly’s AI-QCT, can identify women at high risk for major adverse cardiovascular events (MACE) and improves risk stratification - a population...
The findings demonstrate that AI-QCT features of coronary artery disease (CAD), as detected by Cleerly’s AI-QCT, can identify women at high risk for major adverse cardiovascular events (MACE) and improves risk stratification - a population...
The findings demonstrate that...
03/31/2025
Cath Lab Digest
Statins
CorCal Outcomes Study: Who Needs a Statin? Intermountain Study Compares Prescribing Recommendations Based on Traditional Risk Factors vs. Coronary Artery Calcium Scoring
03/31/2025
The research is part of CorCal Outcomes, a large, randomized clinical trial at Intermountain Health that is comparing the PCE versus CAC score guidance to initiate a statin prescription for patients for primary prevention of coronary heart...
The research is part of CorCal Outcomes, a large, randomized clinical trial at Intermountain Health that is comparing the PCE versus CAC score guidance to initiate a statin prescription for patients for primary prevention of coronary heart...
The research is part of CorCal...
03/31/2025
Cath Lab Digest
CardiAMP Procedure
Cell Therapy
BioCardia Phase 3 CARDIAMP-HF Trial of Novel Cardiac Cell Therapy for Ischemic Heart Failure Shows Increased Survival, Decreased Cardiac Events, and Improved Quality of Life at Two Years
03/31/2025
"In this rigorous CardiAMP-HF Trial, patients who received the novel cell therapy adjunctive to medication experienced decreased mortality and MACCE, with improved quality of life, when compared to those on medication alone," said...
"In this rigorous CardiAMP-HF Trial, patients who received the novel cell therapy adjunctive to medication experienced decreased mortality and MACCE, with improved quality of life, when compared to those on medication alone," said...
"In this rigorous CardiAMP-HF...
03/31/2025
Cath Lab Digest
Peripheral Arterial Disease
New Study Finds Peripheral Artery Disease Often Underdiagnosed and Undertreated; Opportunity to Improve Treatments and Lower Death Rates
03/31/2025
Researchers identified 7,522 patients who had a symptomatic peripheral artery disease diagnosis at Intermountain Health facilities between January 2006 and December 2021 and were seen once in follow-up within at least 18 months of their...
Researchers identified 7,522 patients who had a symptomatic peripheral artery disease diagnosis at Intermountain Health facilities between January 2006 and December 2021 and were seen once in follow-up within at least 18 months of their...
Researchers identified 7,522...
03/31/2025
Cath Lab Digest
TAVR
Evolut Low Risk Trial: Medtronic Evolut TAVR System Shows Durable Clinical Outcomes and Outstanding Valve Performance at 5 Years in Low-Risk AS Patients
03/31/2025
"Results at five years support Evolut's supra-annular, self-expanding TAVR as a safe, effective, and durable alternative to surgery for patients with severe aortic stenosis, regardless of their surgical risk," said Michael J. Reardon, MD.
"Results at five years support Evolut's supra-annular, self-expanding TAVR as a safe, effective, and durable alternative to surgery for patients with severe aortic stenosis, regardless of their surgical risk," said Michael J. Reardon, MD.
"Results at five years support...
03/31/2025
Cath Lab Digest
Calcium Score
Low Coronary Artery Calcium Score is Associated with An Excellent Prognosis Regardless of a Person’s Age, New Intermountain Health Study Finds
03/31/2025
“We found that a zero-plaque burden is not only highly prognostic of good heart health at any age, but also of excellent overall survival,” said Jeffrey L. Anderson, MD, principal investigator of the study.
“We found that a zero-plaque burden is not only highly prognostic of good heart health at any age, but also of excellent overall survival,” said Jeffrey L. Anderson, MD, principal investigator of the study.
“We found that a zero-plaque...
03/31/2025
Cath Lab Digest

CRT Conference Coverage
Disparities in Interventional Cardiology
04/02/2025
Laura Simson
At the Sunday afternoon "Disparities in Interventional Cardiology" session at CRT 2025, experts presented compelling data and discussed the barriers that limit diverse representation in the field, ranging from clinical trials and...
At the Sunday afternoon "Disparities in Interventional Cardiology" session at CRT 2025, experts presented compelling data and discussed the barriers that limit diverse representation in the field, ranging from clinical trials and...
At the Sunday afternoon...
04/02/2025
Journal of Invasive Cardiology
CRT Conference Coverage
Artificial Intelligence in Coronary Artery Disease Diagnosis and Intervention
04/02/2025
Laura Simson
In his Sunday morning session and ensuing panel discussion at CRT 2025, Dr Ran Kornowski of the Rabin Medical Center in Petach-Tikva, Israel, detailed how AI is transforming clinical practice and research in interventional cardiology.
In his Sunday morning session and ensuing panel discussion at CRT 2025, Dr Ran Kornowski of the Rabin Medical Center in Petach-Tikva, Israel, detailed how AI is transforming clinical practice and research in interventional cardiology.
In his Sunday morning session...
04/02/2025
Journal of Invasive Cardiology
Original Contribution
Polidocanol Ablation in Midventricular Obstructive Cardiomyopathy: Novel Approach and Early Outcomes
04/01/2025
Limited data exist regarding polidocanol use for septal ablation, particularly in the context of midventricular obstruction (MVO) . This study presents the first reported use of polidocanol for septal ablation in patients with MVO.
Limited data exist regarding polidocanol use for septal ablation, particularly in the context of midventricular obstruction (MVO) . This study presents the first reported use of polidocanol for septal ablation in patients with MVO.
Limited data exist regarding...
04/01/2025
Journal of Invasive Cardiology
Original Contribution
Heart Rate Variability of Interventional Cardiology Fellows and Attendings and Changes Over Time
04/01/2025
The study examined the stress levels of interventional cardiology (IC) fellows and attendings using both objective (heart rate variability) and subjective (State Trait Anxiety Inventory) metrics across the IC fellowship.
The study examined the stress levels of interventional cardiology (IC) fellows and attendings using both objective (heart rate variability) and subjective (State Trait Anxiety Inventory) metrics across the IC fellowship.
The study examined the stress...
04/01/2025
Journal of Invasive Cardiology
Intravascular Imaging
ECLIPSE Trial: Intravascular Imaging Can Improve Outcomes for Complex Stenting Procedures in Patients with High-Risk Calcified CAD
03/31/2025
“The ECLIPSE trial shows that use of intravascular imaging (IVI) to guide coronary stenting in severely calcified lesions prevents death, stent thrombosis, and unplanned repeat procedures in this high-risk patient population,” says first...
“The ECLIPSE trial shows that use of intravascular imaging (IVI) to guide coronary stenting in severely calcified lesions prevents death, stent thrombosis, and unplanned repeat procedures in this high-risk patient population,” says first...
“The ECLIPSE trial shows that...
03/31/2025
Cath Lab Digest
Aortic Stenosis
New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients
03/31/2025
New data from DETECT AS and the EARLY TAVR Trial were presented at ACC.25 in Chicago, addressing the critical needs of patients with structural heart disease.
New data from DETECT AS and the EARLY TAVR Trial were presented at ACC.25 in Chicago, addressing the critical needs of patients with structural heart disease.
New data from DETECT AS and the...
03/31/2025
Cath Lab Digest
CAD in Women
New Intermountain Health Study Finds Gap Between Heart Disease Outcomes in Men and Women Has Narrowed Over Past 20 Years  
03/31/2025
Women studied tended to be older with more comorbidities (like high blood pressure, diabetes, and history of stroke and heart failure), have more stable chest pain, and experience less severe chest pain or heart attack when they came into the...
Women studied tended to be older with more comorbidities (like high blood pressure, diabetes, and history of stroke and heart failure), have more stable chest pain, and experience less severe chest pain or heart attack when they came into the...
Women studied tended to be older...
03/31/2025
Cath Lab Digest
AI
HeartFocus Clinical Trial Proves AI Can Empower Novices to Deliver Diagnostic-Quality Cardiac Ultrasounds
03/31/2025
Results showed that 100% of exams conducted by novices using HeartFocus met the diagnostic standards for all primary endpoints, with a strong correlation to expert-acquired scans across qualitative and quantitative assessments.
Results showed that 100% of exams conducted by novices using HeartFocus met the diagnostic standards for all primary endpoints, with a strong correlation to expert-acquired scans across qualitative and quantitative assessments.
Results showed that 100% of...
03/31/2025
Cath Lab Digest
plaque analysis
CONFIRM2 Registry: Late-Breaking Clinical Trial Results Demonstrate the Predictive Power of Cleerly's AI-QCT for Women’s Cardiovascular Risk at ACC.25
03/31/2025
The findings demonstrate that AI-QCT features of coronary artery disease (CAD), as detected by Cleerly’s AI-QCT, can identify women at high risk for major adverse cardiovascular events (MACE) and improves risk stratification - a population...
The findings demonstrate that AI-QCT features of coronary artery disease (CAD), as detected by Cleerly’s AI-QCT, can identify women at high risk for major adverse cardiovascular events (MACE) and improves risk stratification - a population...
The findings demonstrate that...
03/31/2025
Cath Lab Digest
Statins
CorCal Outcomes Study: Who Needs a Statin? Intermountain Study Compares Prescribing Recommendations Based on Traditional Risk Factors vs. Coronary Artery Calcium Scoring
03/31/2025
The research is part of CorCal Outcomes, a large, randomized clinical trial at Intermountain Health that is comparing the PCE versus CAC score guidance to initiate a statin prescription for patients for primary prevention of coronary heart...
The research is part of CorCal Outcomes, a large, randomized clinical trial at Intermountain Health that is comparing the PCE versus CAC score guidance to initiate a statin prescription for patients for primary prevention of coronary heart...
The research is part of CorCal...
03/31/2025
Cath Lab Digest

April 2019 Volume 31 E Issue 4

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