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Transcatheter Aortic Valve Replacement in a Patient With Pre-existing Left Ventricular Pseudoaneurysm: The Importance of Pre- and Intra-procedural Imaging

Avionam Shiran, MD; Alexander Fuks, MD; Keren Zissman, MD; Ronen Jaffe, MD

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Any views and opinions expressed are those of the author(s) and/or participants and do not necessarily reflect the views, policy, or position of the Journal of Invasive Cardiology or HMP Global, their employees, and affiliates. 


J INVASIVE CARDIOL 2024. doi:10.25270/jic/24.00143. Epub May 20, 2024.


An 85-year-old man with a history of myocardial infarction and coronary bypass surgery presented with severe symptomatic aortic stenosis. Echocardiography revealed pressure gradients of 73/40 mm Hg across the aortic valve, an aortic valve area of 0.74 cm2, and a 35% ejection fraction. The left ventricular (LV) posterior wall was akinetic, with a large lateral wall pseudoaneurysm. Computed tomography angiography confirmed a large basal lateral left ventricular (LV) pseudoaneurysm (4.9 × 4.7 × 4.5 cm) (Figure 1A and B). The patient was at high risk for surgical valve replacement and was referred for a transcatheter aortic valve replacement (TAVR). We were concerned that inadvertent insertion of a stiff guidewire into the pseudoaneurysm during TAVR would cause cardiac rupture.

TAVR was performed under general anesthesia with transesophageal echocardiography (TEE) guidance. Initial positioning of a straight-tip guidewire within the pseudoaneurysm (Figure 1C) was detected by TEE and the wire was repositioned to the LV apex (Figure 1D). A stiff pre-shaped guidewire (Confida; Medtronic) was then positioned within the LV apex (Figure 1E) and direct implantation of a 26-mm Sapien S3 valve (Edwards) was performed successfully (Figure 1F). The patient recovered uneventfully. This case emphasizes the importance of multi-modality pre- and intra-procedural imaging during TAVR.

 

Figure.  CTA
Figure. (A) CTA showed a large basal lateral LV PA. (B) Three-dimensional CTA reconstruction showed the pseudoaneurysm (asterisk). (C) Transesophageal echocardiography showed the initial positioning of the straight-tip guidewire (arrow) across the AV within the PA. (D) The straight-tip guidewire (arrow) was repositioned within the LV apex. (E) Fluoroscopy image showed stiff guidewire positioned at the LV apex. (F) The deployed prosthetic aortic valve. AV = aortic valve; CTA = computed tomography angiography; LV = left ventricular; PA = pseudoaneurysm.

 

Affiliations and Disclosures

From the Department of Cardiology, Lady Davis Carmel Medical Center, Haifa, Israel.

Disclosures: The authors report no financial relationships or conflicts of interest regarding the content herein.

Consent statement: The patient gave written informed consent for performing the procedure. Verbal informed consent was given by the patient to present the procedural details anonymously.

Address for correspondence: Ronen Jaffe, MD, Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center, 7 Michal St, Haifa 34362, Israel. Email: jaffe@clalit.org.il


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