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Research in Review

Research in Review Focus on Cancer

June 2022

J Clin Pathways. 2022;8(5):12.

Immune Checkpoint Inhibitors May Have Been Used Inappropriately in Half of Study Patients With Advanced Cancer Who Were Near the End of Life

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced cancer and been shown to extend progression-free survival and overall survival in patients with a variety of cancers. In part because of the increasing use of ICIs, the systemic treatment of patients with advanced cancer who are near the end of life has been increasing. However, data on additional factors associated with this trend are limited.

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