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Addition of Durvalumab, Bevacizumab to TACE for Hepatocellular Carcinoma Improves PFS
At the ASCO Gastrointesinal Cancers Symposium, Riccardo Lencioni, MD, Pisa University School of Medicine, Pisa, Italy, discussed the results from the phase 3 EMERALD-1 study. This trial found the combination of transarterial chemoembolization (TACE) and durvalumab, followed by durvalumab and bevacizumab, improved the progression-free survival (PFS) among patients with hepatocellular carcinoma, compared with TACE alone.
Source:
Lencioni R, Kudo M, Erinjeri J, et al. EMERALD-1: A phase 3, randomized, placebo-controlled study of transarterial chemoembolization combined with durvalumab with or without bevacizumab in participants with unresectable hepatocellular carcinoma eligible for embolization. Presented at 2024 ASCO Gastrointestinal Cancer Symposium; January 18-20, 2024; San Francisco, California. Abstract LBA432