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Less Invasive Surgery for Esophageal Cancer Proves Better Option
McKeown minimally invasive esophagectomy (McKeown-MIE) was associated with greater rates of long-term survival in treating patients with esophageal cancer (EC) over McKeown open esophagectomy (McKeown-OE) in a recent study.
“McKeown minimally invasive esophagectomy (McKeown-MIE) offers advantages in short-term outcomes compared with McKeown open esophagectomy (McKeown-OE); however, debate as to whether MIE is equivalent or better than OE regarding survival outcomes is ongoing,” the authors reported. “The aim of this study was to compare long-term survival between McKeown-MIE and McKeown-OE in a large cohort of esophageal cancer (EC) patients.”
Using a database from the Thoracic Surgery Department at Henan Cancer Hospital in Henan, China, researchers reviewed outcomes among patients with resectable EC who underwent McKeown-MIE or McKeown-OE between January 1, 2015, and January 6, 2018.
The retrospective study included 502 patients with EC, median age 63 years, and well-balanced clinical characteristics throughout both groups. The McKeown-MIE cohort included 306 patients; 196 were assigned to the McKeown-OE group.
“There was a significantly shorter mean operative time (269.76 min vs. 321.14 min) in the McKeown-OE group. The 30-day and in-hospital mortality rates were 0, and there was no difference in 90-day mortality between the groups. The postoperative stay was shorter in the McKeown-MIE group and was 14 days and 18 days in the MIE and OE groups, respectively. The overall survival? (OS) at 60 months was 58.8% and 41.6% in the MIE and OE groups, respectively,” the authors concluded.
—Angelique Platas
Reference
Zheng Y, Li Y, Liu X. et al. Minimally invasive versus open McKeown for patients with esophageal cancer: a retrospective study. Ann Surg Oncol Published May 2021
