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News
RSV Vaccine Combo Shows Promise for Enhanced Protection
08/22/2023
Jolynn Tumolo
According to recent research, including recombinant RSV prefusion conformation-stabilized fusion protein in the vaccine improved the overall effectiveness in generating immune reactions in older patients.
According to recent research, including recombinant RSV prefusion conformation-stabilized fusion protein in the vaccine improved the overall effectiveness in generating immune reactions in older patients.
According to recent research,...
08/22/2023
First Report Managed Care
News
RSV Prefusion F Vaccine Prevents RSV Illness in Older Adults
08/10/2023
Jolynn Tumolo
Recent clinical trial findings indicate that the RSVpreF vaccine demonstrated efficacy in preventing RSV-associated respiratory illnesses in older adults with no significant safety concerns.
Recent clinical trial findings indicate that the RSVpreF vaccine demonstrated efficacy in preventing RSV-associated respiratory illnesses in older adults with no significant safety concerns.
Recent clinical trial findings...
08/10/2023
First Report Managed Care
News
RSV Vaccination in US Older Adults Could Save Up to $1 Billion Per Season
07/24/2023
Jolynn Tumolo
"Our analysis provides contemporary estimates of the population-level RSV disease burden and insights into the economic value drivers for RSV vaccination," said researchers. 
"Our analysis provides contemporary estimates of the population-level RSV disease burden and insights into the economic value drivers for RSV vaccination," said researchers. 
"Our analysis provides...
07/24/2023
First Report Managed Care
News
Cell-Based Relative Potency Assay Assessed for RSV Vaccine Development
07/19/2023
Julie Gould
Researchers tested RSV mRNA vaccine V171 through a relative potency assay to assess its ability to induce humoral and cellular immunity responses. 
Researchers tested RSV mRNA vaccine V171 through a relative potency assay to assess its ability to induce humoral and cellular immunity responses. 
Researchers tested RSV mRNA...
07/19/2023
First Report Managed Care
News
Trial Finds Lower Viral Load, Symptom Scores With MVA-BN-RSV Vaccine
06/27/2023
Jolynn Tumolo
The findings of a phase 2a trial show the MVA-BN-RSV vaccine reduced respiratory syncytial virus load, symptoms, and infections while eliciting immune responses.
The findings of a phase 2a trial show the MVA-BN-RSV vaccine reduced respiratory syncytial virus load, symptoms, and infections while eliciting immune responses.
The findings of a phase 2a trial...
06/27/2023
First Report Managed Care
News
Mapping the Diversity and Evolution of RSV T Cell Epitopes for Vaccine Design
06/26/2023
Julie Gould
Human respiratory syncytial virus (RSV) strains cluster into distinct groups based on T cell epitope profiles, indicating divergent immunogenic profiles and highlighting the need for different vaccine strategies for RSV-A and RSV-B groups.
Human respiratory syncytial virus (RSV) strains cluster into distinct groups based on T cell epitope profiles, indicating divergent immunogenic profiles and highlighting the need for different vaccine strategies for RSV-A and RSV-B groups.
Human respiratory syncytial...
06/26/2023
First Report Managed Care
News
Vaccine Protects Against RSV-Mediated Lower Respiratory Tract Disease in Older Adults
04/26/2023
Jolynn Tumolo
Researchers evaluated the Ad26.RSV.pre-F vaccine's efficacy in a proof-of-concept study involving several thousand older adults.
Researchers evaluated the Ad26.RSV.pre-F vaccine's efficacy in a proof-of-concept study involving several thousand older adults.
Researchers evaluated the...
04/26/2023
First Report Managed Care
News
New Respiratory Syncytial Virus Prevention Options on the Horizon for Older Adults
04/21/2023
Jolynn Tumolo
“It is likely that multiple immunization strategies with complementary value, unique advantages, and use-case scenarios will shape the RSV prevention landscape," researchers said.
“It is likely that multiple immunization strategies with complementary value, unique advantages, and use-case scenarios will shape the RSV prevention landscape," researchers said.
“It is likely that multiple...
04/21/2023
Pharmacy Learning Network
News
RSV Vaccine Candidate Demonstrates Safety but no Increase in RSV-Neutralizing Antibody Titers
04/20/2023
Jolynn Tumolo
Researchers said outcomes will likely improve with future vaccine modifications and alterations to the study population.
Researchers said outcomes will likely improve with future vaccine modifications and alterations to the study population.
Researchers said outcomes will...
04/20/2023
First Report Managed Care
News
RSV Vaccine Efficacious for Older Adults Regardless of Underlying Conditions
03/31/2023
Maria Asimopoulos
Data from an ongoing phase 3 trial suggest a vaccine for respiratory syncytial virus is efficacious for preventing infection and severe disease in older adults.
Data from an ongoing phase 3 trial suggest a vaccine for respiratory syncytial virus is efficacious for preventing infection and severe disease in older adults.
Data from an ongoing phase 3...
03/31/2023
First Report Managed Care

Behind the Bill

Behind the Bill
SCOTUS Takes on the Nondelegation Doctrine: Surprising Reactions and What They Mean for Agency Power
04/02/2025
Katie Hayes, MJ
The Supreme Court recently heard arguments in Federal Communication Commission (FCC) v Consumers’ Research, a case that I covered in February and one that could dramatically reshape federal agency authority through the nondelegation...
The Supreme Court recently heard arguments in Federal Communication Commission (FCC) v Consumers’ Research, a case that I covered in February and one that could dramatically reshape federal agency authority through the nondelegation...
The Supreme Court recently heard...
04/02/2025
First Report Managed Care
Behind the Bill
Dr Oz’s Prescription for Making Medicaid “Viable at Every Level”
03/26/2025
Katie Hayes, MJ
On Tuesday, March 25, 2025, the Senate Finance Committee voted to advance Dr Mehmet Oz in his confirmation as the next head of the Centers for Medicare and Medicaid Services (CMS).1 The full Senate vote is expected “soon” (whatever that...
On Tuesday, March 25, 2025, the Senate Finance Committee voted to advance Dr Mehmet Oz in his confirmation as the next head of the Centers for Medicare and Medicaid Services (CMS).1 The full Senate vote is expected “soon” (whatever that...
On Tuesday, March 25, 2025, the...
03/26/2025
First Report Managed Care
Behind the Bill
The $880 Billion Question Continues: Dr Oz's Confirmation and the Future of Medicaid
03/19/2025
Katie Hayes, MJ
Last week, I explored the $880 billion question facing Congress—whether lawmakers could achieve their budget goals without cutting Medicaid. This week, that question took center stage as Dr Mehmet Oz, President Trump's nominee to lead the...
Last week, I explored the $880 billion question facing Congress—whether lawmakers could achieve their budget goals without cutting Medicaid. This week, that question took center stage as Dr Mehmet Oz, President Trump's nominee to lead the...
Last week, I explored the $880...
03/19/2025
First Report Managed Care
Behind the Bill
The $880 Billion Question: Can Congress Cut Spending Without Touching Medicaid?
03/12/2025
Katie Hayes, MJ
I’d like to step away from administrative law for a moment to provide a quick update on Medicaid. With news coming from all sides, what does the future of Medicaid actually look like? The House of Representatives narrowly passed a budget...
I’d like to step away from administrative law for a moment to provide a quick update on Medicaid. With news coming from all sides, what does the future of Medicaid actually look like? The House of Representatives narrowly passed a budget...
I’d like to step away from...
03/12/2025
First Report Managed Care
Behind the Bill
RFK Jr’s Public Comment Ban: The Silent Shift in Health Care Rulemaking
03/05/2025
Katie Hayes, MJ
The erosion of administrative law continues, and with it, the dismantling of decades-long precedent. In June, the Supreme Court overturned a 40-year-old doctrine that allowed federal agencies to interpret their own ambiguous statutes. Later...
The erosion of administrative law continues, and with it, the dismantling of decades-long precedent. In June, the Supreme Court overturned a 40-year-old doctrine that allowed federal agencies to interpret their own ambiguous statutes. Later...
The erosion of administrative...
03/05/2025
First Report Managed Care
Behind the Bill
Prevention Over Pills? The First 2 Weeks of Health Care’s New Direction
02/26/2025
Katie Hayes, MJ
The dust has barely settled from Robert F Kennedy Jr’s confirmation as Secretary of Health and Human Services (HHS), but the changes are already coming fast and furious—a key theme of the Trump Administration’s actions within the last several...
The dust has barely settled from Robert F Kennedy Jr’s confirmation as Secretary of Health and Human Services (HHS), but the changes are already coming fast and furious—a key theme of the Trump Administration’s actions within the last several...
The dust has barely settled from...
02/26/2025
First Report Managed Care
Behind the Bill
The Nondelegation Doctrine: The Next Constitutional Showdown (Part 2)
02/19/2025
Katie Hayes, MJ
Last week, I explored the potential revival of the nondelegation doctrine through Federal Communication Commission v Consumers’ Research. Today, I want to examine what this could mean for health care regulation by considering the parallels...
Last week, I explored the potential revival of the nondelegation doctrine through Federal Communication Commission v Consumers’ Research. Today, I want to examine what this could mean for health care regulation by considering the parallels...
Last week, I explored the...
02/19/2025
First Report Managed Care
Behind the Bill
The Nondelegation Doctrine: The Next Constitutional Showdown (Part 1)
02/12/2025
Katie Hayes, MJ
Just when you thought the dust had settled from the Chevron decision, the Supreme Court is gearing up to hear arguments in Federal Communications Commission v Consumers' Research next month, potentially reviving the long-dormant nondelegation...
Just when you thought the dust had settled from the Chevron decision, the Supreme Court is gearing up to hear arguments in Federal Communications Commission v Consumers' Research next month, potentially reviving the long-dormant nondelegation...
Just when you thought the dust...
02/12/2025
First Report Managed Care
Behind the Bill
No, President Trump Did Not Actually Sign an Executive Order That Would Increase Drug Costs for Beneficiaries
02/05/2025
Katie Hayes, MJ
On inauguration day, President Trump issued an executive order rescinding several Biden-era health care initiatives, including 3 experimental drug pricing models developed by the Center for Medicare and Medicaid Innovation (CMMI). Oh boy did...
On inauguration day, President Trump issued an executive order rescinding several Biden-era health care initiatives, including 3 experimental drug pricing models developed by the Center for Medicare and Medicaid Innovation (CMMI). Oh boy did...
On inauguration day, President...
02/05/2025
First Report Managed Care
Behind the Bill
Robert F. Kennedy Jr’s Confirmation and the Unexpected Turn in the Drug Pricing Debate
01/29/2025
Katie Hayes, MJ
The Plot Thickens in Drug Pricing Drama Just when you thought the drug pricing debate couldn't get more interesting, Robert F. Kennedy Jr adds an unexpected twist. During closed-door Senate meetings, President Trump’s US Department of...
The Plot Thickens in Drug Pricing Drama Just when you thought the drug pricing debate couldn't get more interesting, Robert F. Kennedy Jr adds an unexpected twist. During closed-door Senate meetings, President Trump’s US Department of...
The Plot Thickens in Drug...
01/29/2025
First Report Managed Care

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Trending Articles

News
Long-Wave Infrared Thermography Helps LTACH Achieve Pressure Injury Success
04/25/2023
Jolynn Tumolo
“The LTACH facility maintained a zero hospital-acquired pressure injury rate for 10 months after implementation of long-wave infrared thermography," researchers reported.
“The LTACH facility maintained a zero hospital-acquired pressure injury rate for 10 months after implementation of long-wave infrared thermography," researchers reported.
“The LTACH facility maintained a...
04/25/2023
First Report Managed Care
Headshot of Barbara Konkle, MD, on a blue background underneath the PopHealth Perspectives logo.
Podcasts
Discussing a Novel Factor VIII Replacement Therapy for Patients With Hemophilia
05/24/2023
Maria Asimopoulos
Barbara Konkle, MD, professor of medicine, Division of Hematology, University of Washington; research director, Washington Center for Bleeding Disorders; and director, Hemostasis, Platelet Immunology and Genomics Laboratory at Bloodworks...
Barbara Konkle, MD, professor of medicine, Division of Hematology, University of Washington; research director, Washington Center for Bleeding Disorders; and director, Hemostasis, Platelet Immunology and Genomics Laboratory at Bloodworks...
Barbara Konkle, MD, professor of...
05/24/2023
First Report Managed Care
Formulary Frontlines®
Challenges, Treatment Options, and Costs Linked With Upper Tract Urothelial Carcinoma
06/20/2023
Julie Gould
Bladder cancer was the sixth most common cancer type in the United States in 2020, behind breast, lung, prostate, colon, and skin cancers.
Bladder cancer was the sixth most common cancer type in the United States in 2020, behind breast, lung, prostate, colon, and skin cancers.
Bladder cancer was the sixth...
06/20/2023
First Report Managed Care
News
Medicare Could Save $1 Billion by Considering Added Benefit of Expensive Part B Drugs
07/18/2023
Jolynn Tumolo
Researchers find that Medicare could potentially save $1 billion by considering the added therapeutic benefit of expensive Part B drugs and implementing reference pricing.
Researchers find that Medicare could potentially save $1 billion by considering the added therapeutic benefit of expensive Part B drugs and implementing reference pricing.
Researchers find that Medicare...
07/18/2023
First Report Managed Care
News
New Platform Leverages Real-World Evidence for Type 2 Inflammation Immunological Disease Research
08/07/2023
Hannah Musick
Researchers introduce Immunolab, a platform that generates real-world evidence to provide insights and conduct research on immunological diseases related to type 2 inflammation.
Researchers introduce Immunolab, a platform that generates real-world evidence to provide insights and conduct research on immunological diseases related to type 2 inflammation.
Researchers introduce Immunolab,...
08/07/2023
First Report Managed Care

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