For their annual debate at the AIBD conference, this year Drs Corey Siegel and Miguel Regueiro took on the topic of whether to go big--using large molecule biologics--or to go small, with oral small molecule treatments, when caring for patients with AIBD. Hear their different viewpoints here!

Miguel Regueiro, MD, is professor of medicine and chair of the Digestive Disease & Surgery Institute at Cleveland Clinic in Cleveland, Ohio. Corey Siegel, MD, is the section chief of Gastroenterology and Hepatology and the codirector of the Inflammatory Bowel Disease (IBD) Center at the Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire.