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Ulcerative Colitis News

FDA alert
FDA Alert
FDA Approves Guselkumab for Moderate to Severe Ulcerative Colitis
09/12/2024
Rebecca Mashaw
Johnson & Johnson’s guselkumab is the first and only fully-human, dual-acting monoclonal antibody that blocks IL-23 and binds to CD64.
Johnson & Johnson’s guselkumab is the first and only fully-human, dual-acting monoclonal antibody that blocks IL-23 and binds to CD64.
Johnson & Johnson’s guselkumab...
09/12/2024
Advances in Inflammatory Bowel Disease Network
News
Upadacitinib vs Tofacitinib for Clinical Remission in Ulcerative Colitis
08/09/2024
Jolynn Tumolo
Investigators conducted a head-to-head trial of the 2 JAK inhibitors to determine which performed best in achieving steroid-free clinical remission among patients with ulcerative colitis
Investigators conducted a head-to-head trial of the 2 JAK inhibitors to determine which performed best in achieving steroid-free clinical remission among patients with ulcerative colitis
Investigators conducted a...
08/09/2024
Advances in Inflammatory Bowel Disease Network
News
Colorectal Cancer Risk Higher Among Patients WIth PSC, With or Without IBD
07/24/2024
Jolynn Tumolo
Extended screening and surveillance are recommended for all patients with primary sclerosing cholangitis, but those with comorbid inflammatory bowel disease are at highest risk.
Extended screening and surveillance are recommended for all patients with primary sclerosing cholangitis, but those with comorbid inflammatory bowel disease are at highest risk.
Extended screening and...
07/24/2024
Gastroenterology
News
Fecal Calprotectin Proves an Effective Biomarker of Endoscopic Inflammation in UC
04/11/2024
Jolynn Tumolo
Mayo endoscopic subscores correlated with fecal calprotectin scores, which also predicted remission.
Mayo endoscopic subscores correlated with fecal calprotectin scores, which also predicted remission.
Mayo endoscopic subscores...
04/11/2024
Advances in Inflammatory Bowel Disease Network
Bharati Kochar
Conference Coverage
Bharati Kochar, MD, on Comparative Effectiveness in Positioning Therapies in Ulcerative Colitis
04/10/2024
Dr Bharati Kochar talks about considering the efficacy-safety relationship to avoid longstanding corticosteroid use or the use of less effective agents in biologic-exposed populations at the AIBD regional meeting in Boston.
Dr Bharati Kochar talks about considering the efficacy-safety relationship to avoid longstanding corticosteroid use or the use of less effective agents in biologic-exposed populations at the AIBD regional meeting in Boston.
Dr Bharati Kochar talks about...
04/10/2024
Advances in Inflammatory Bowel Disease Network
News
Extended Mirikizumab Induction Benefits Slower Responders in UC Trials
03/20/2024

Jolynn Tumolo

Jolynn Tumolo
LUCENT trials found that 24-week induction period generated response in half of patients.
LUCENT trials found that 24-week induction period generated response in half of patients.
LUCENT trials found that 24-week...
03/20/2024
Advances in Inflammatory Bowel Disease Network
Conference Coverage
Bowel Urgency Reflected in Patient Perceptions of UC Severity
02/20/2024
How patients perceive the severity of their ulcerative colitis is affected by the frequency of bowel urgency episodes and accidents, researchers reported at the American College of Gastroenterology Postgraduate Course.
How patients perceive the severity of their ulcerative colitis is affected by the frequency of bowel urgency episodes and accidents, researchers reported at the American College of Gastroenterology Postgraduate Course.
How patients perceive the...
02/20/2024
Advances in Inflammatory Bowel Disease Network
Conference Coverage
ELEVATE UC Trials Demonstrate Response to Treatment with Etrasimod
01/08/2024
Priyam Vora
Rectal bleeding and stool frequency are key determinants among patients with ulcerative colitis and can help guide therapy decisions.
Rectal bleeding and stool frequency are key determinants among patients with ulcerative colitis and can help guide therapy decisions.
Rectal bleeding and stool...
01/08/2024
Advances in Inflammatory Bowel Disease Network
News
FDA Approves Interchangeable Biosimilar for Ustekinumab
11/02/2023
The biosimilar was also approved to treat moderate to severe plaque psoriasis and active psoriatic arthritis.
The biosimilar was also approved to treat moderate to severe plaque psoriasis and active psoriatic arthritis.
The biosimilar was also approved...
11/02/2023
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Approves Mirikizumab for Adults With Moderately to Severely Active Ulcerative Colitis
10/27/2023
Rebecca Mashaw
The LUCENT trial demonstrated the safety and efficacy of the interleukin-23/p19 subunit inhibitor.
The LUCENT trial demonstrated the safety and efficacy of the interleukin-23/p19 subunit inhibitor.
The LUCENT trial demonstrated...
10/27/2023
Advances in Inflammatory Bowel Disease Network

Latest News

News
Upadacitinib Demonstrates Long-Term Efficacy in Crohn’s Disease With Acceptable Safety Profile
04/17/2025
Jessica Garlewicz
These results support the continued development and clinical use of upadacitinib as a treatment strategy for patients with moderate-to-severe Crohn’s disease.
These results support the continued development and clinical use of upadacitinib as a treatment strategy for patients with moderate-to-severe Crohn’s disease.
These results support the...
04/17/2025
Advances in Inflammatory Bowel Disease Network
News
Wearable Sensors Show Promise for Noninvasive Monitoring of IBD Inflammatory Markers
04/03/2025
Jessica Garlewicz
The findings suggest strong correlation between sweat-based readings and conventional serum and stool biomarkers, indicating potential for real-time disease monitoring.
The findings suggest strong correlation between sweat-based readings and conventional serum and stool biomarkers, indicating potential for real-time disease monitoring.
The findings suggest strong...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
Guselkumab Demonstrates Efficacy and Safety in Phase 3 Study for Moderate to Severe Crohn’s Disease
04/03/2025
Jessica Garlewicz
Subcutaneous guselkumab showed significant clinical and endoscopic efficacy in patients with moderately to severely active Crohn’s disease.
Subcutaneous guselkumab showed significant clinical and endoscopic efficacy in patients with moderately to severely active Crohn’s disease.
Subcutaneous guselkumab showed...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
Early Response to Upadacitinib Predicts Long-Term Improvements in Crohn’s Disease
04/03/2025
Jessica Garlewicz
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
MASLD Linked to Worse Clinical Outcomes in Hospitalized Crohn’s Disease Patients
04/03/2025
Jessica Garlewicz
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409...
04/03/2025
Gastroenterology
News
VCE-Guided Treat-to-Target Strategy Reduces Flares in Crohn’s Disease Remission
04/01/2025
Jessica Garlewicz
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility...
04/01/2025
Advances in Inflammatory Bowel Disease Network
News
Postoperative Microbiome Profiles Predict Crohn’s Disease Recurrence
03/25/2025
Jessica Garlewicz
A multicenter prospective study has identified specific mucosa-associated microbiome changes that precede postoperative recurrence of Crohn’s disease.
A multicenter prospective study has identified specific mucosa-associated microbiome changes that precede postoperative recurrence of Crohn’s disease.
A multicenter prospective study...
03/25/2025
Advances in Inflammatory Bowel Disease Network
News
Advances in Postoperative Crohn’s Disease Management Aim to Reduce Recurrence Rates
03/25/2025
Jessica Garlewicz
Despite significant progress in medical therapies for Crohn’s disease, a substantial number of patients still require surgical intervention.
Despite significant progress in medical therapies for Crohn’s disease, a substantial number of patients still require surgical intervention.
Despite significant progress in...
03/25/2025
Advances in Inflammatory Bowel Disease Network
FDA Alert
FDA Approves Both SC and IV Guselkumab for Crohn's Disease Among Adult Patients
03/24/2025
Rebecca Mashaw
This clearance follows last year's approval for ulcerative colitis and the first approval for subcutaneous and intravenous formulations to induce remission in adult patients with moderately to severely active Crohn's disease.
This clearance follows last year's approval for ulcerative colitis and the first approval for subcutaneous and intravenous formulations to induce remission in adult patients with moderately to severely active Crohn's disease.
This clearance follows last...
03/24/2025
Advances in Inflammatory Bowel Disease Network
News
Risankizumab Shows Efficacy in Treating Pouch Complications
03/19/2025
Rebecca Mashaw
Half of a small cohort of patients with Crohn’s disease of the pouch experienced clinical remission after 12 weeks of therapy with the IL-23 inhibitor.
Half of a small cohort of patients with Crohn’s disease of the pouch experienced clinical remission after 12 weeks of therapy with the IL-23 inhibitor.
Half of a small cohort of...
03/19/2025
Advances in Inflammatory Bowel Disease Network

Latest Podcasts

IBD Drive time logo
Podcast
IBD Drive Time: Sara Horst, MD, on the Best of ECCO
04/22/2025
Raymond Cross, MD; Sara Horst, MD
Host Raymond Cross, MD, talks with Dr Sara Horst from Vanderbilt University about their picks for the most interesting and important presentations on inflammatory bowel disease at ECCO 2025.
Host Raymond Cross, MD, talks with Dr Sara Horst from Vanderbilt University about their picks for the most interesting and important presentations on inflammatory bowel disease at ECCO 2025.
Host Raymond Cross, MD, talks...
04/22/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Perioperative Optimization of Patients With IBD
04/09/2025
Raymond Cross, MD; Karen Zaghiyan, MD; Kelly Issokson, MS, RD
Host Dr Raymond Cross leads the discussion on perioperative optimization in patients with IBD with colorectal surgeon Karen Zaghiyan, MD, and dietitian Kelly Isaacson in this episode of IBD Drive Time.
Host Dr Raymond Cross leads the discussion on perioperative optimization in patients with IBD with colorectal surgeon Karen Zaghiyan, MD, and dietitian Kelly Isaacson in this episode of IBD Drive Time.
Host Dr Raymond Cross leads the...
04/09/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Freddy Caldera, DO, on Disease Prevention in IBD
03/17/2025
Millie D. Long, MD, MPH; Freddy Caldera, DO
Freddy Caldera, DO, PhD, and IBD Drive Time cohost Millie Long, MD, discuss the new AGA best practice advice on preventing diseases and monitoring for complications in patients with inflammatory bowel disease.
Freddy Caldera, DO, PhD, and IBD Drive Time cohost Millie Long, MD, discuss the new AGA best practice advice on preventing diseases and monitoring for complications in patients with inflammatory bowel disease.
Freddy Caldera, DO, PhD, and IBD...
03/17/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Detecting and Managing Anorectal Cancer
03/04/2025
Raymond Cross, MD; Millie D. Long, MD, MPH; Jessica Korman
Andrea Bafford, MD, and Jessica Korman, MD, join Drs Raymond Cross and Millie Long to review the challenges of detecting, diagnosing, and managing anorectal cancer among patients with inflammatory bowel disease.
Andrea Bafford, MD, and Jessica Korman, MD, join Drs Raymond Cross and Millie Long to review the challenges of detecting, diagnosing, and managing anorectal cancer among patients with inflammatory bowel disease.
Andrea Bafford, MD, and Jessica...
03/04/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcasts
IBD Drive Time: Jami Kinnucan, MD, on Using Cannabis in IBD
02/12/2025
Jami Kinnucan; Raymond Cross, MD; Millie D. Long, MD, MPH
Jami Kinnucan, MD, reviews the facts and fallacies about the use of cannabis for the treatment of inflammatory bowel disease, and how to discuss the issue with patients, with IBD Drive Time hosts Raymond Cross, MD, and Millie Long, MD.
Jami Kinnucan, MD, reviews the facts and fallacies about the use of cannabis for the treatment of inflammatory bowel disease, and how to discuss the issue with patients, with IBD Drive Time hosts Raymond Cross, MD, and Millie Long, MD.
Jami Kinnucan, MD, reviews the...
02/12/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Lin Chang, MD, on IBS in IBD
01/27/2025
Raymond Cross, MD
Dr Lin Chang joins hosts Raymond Cross, MD, and Millie Long, MD, to discuss how patient with inflammatory bowel disease may also have underlying irritable bowel syndrome, how to diagnose the condition, and the best options for treatment.
Dr Lin Chang joins hosts Raymond Cross, MD, and Millie Long, MD, to discuss how patient with inflammatory bowel disease may also have underlying irritable bowel syndrome, how to diagnose the condition, and the best options for treatment.
Dr Lin Chang joins hosts Raymond...
01/27/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Sara Horst, MD, on the Best of ACG
01/20/2025
Raymond Cross, MD
Drs Ray Cross and Millie Long discuss with guest Dr Sara Horst the best presentations and abstracts on inflammatory bowel disease from the American College of Gastroenterology scientific meeting held in October.
Drs Ray Cross and Millie Long discuss with guest Dr Sara Horst the best presentations and abstracts on inflammatory bowel disease from the American College of Gastroenterology scientific meeting held in October.
Drs Ray Cross and Millie Long...
01/20/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Frank Scott, MD, on the AGA Guidelines for Ulcerative Colitis Management
12/30/2024
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast,...
12/30/2024
Advances in Inflammatory Bowel Disease Network
Millie Long
Video
Millie Long, MD, on Comparative Effectiveness in Ulcerative Colitis
10/21/2024
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation...
10/21/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Drs James Lewis and Laura Raffals on SPARC
10/21/2024
Dr Raymond Cross hosts Drs James Lewis and Laura Raffals in a discussion of SPARC, a study of adults with inflammatory bowel disease in which patients are followed prospectively to collect data about to allow prediction of disease course and...
Dr Raymond Cross hosts Drs James Lewis and Laura Raffals in a discussion of SPARC, a study of adults with inflammatory bowel disease in which patients are followed prospectively to collect data about to allow prediction of disease course and...
Dr Raymond Cross hosts Drs James...
10/21/2024
Advances in Inflammatory Bowel Disease Network

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