Antimicrobial Efficacy Evaluation of a Natural Product against Bacterial and Mold Wound Pathogens

There is an increasing threat from microbial contamination and infections caused by antibiotic resistant and hard-to-treat pathogens including molds. Current Strategies for eradication of molds are often ineffective, complex and costly. A candidate product is being introduced as an effective natural product for eradication of molds and other hard-to-treat infectious agents. The increasing prevalence of wound infections caused by molds calls for the development of new and effective treatment strategies. Therefore, we evaluated the antimicrobial property of this candidate natural product. We conducted Minimal Inhibitory Concentrations (MIC) for various infectious agents including molds. MIC testing was conducted by microdilution assay based on the clinical and laboratory standard institute (CLSI) methodology to investigate the degree of bactericidal and fungicidal activity of the product. The organisms tested included wound pathogens such as Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, MRSA (methicillin-resistant Staphylococcus aureus), Candida albicans, Candida parapsilosis, Aspergillus fumigatus, Fusarium solani. The results demonstrated this cost effective natural product is a promising broad-spectrum antimicrobial. The product can be used as a decontaminant with various downstream applications including a “wound infection” control measure in clinical and non-clinical settings.