3-Dimensional Wound Matrix for Complex Pressure Ulcers: A Case Series Analysis

Introduction: Pressure ulcers are a significant healthcare challenge, particularly for individuals with limited mobility or impaired circulation. These ulcers can become deeply entrenched, with tunneling and undermining, leading to prolonged healing times and substantial costs for the healthcare system. This analysis examines the use of Miro3D (Reprise Biomedical, Inc., Plymouth, MN), a three-dimensional (3D) porcine-derived wound matrix, in patients with complex pressure ulcers characterized by tunneling and undermining. The successful application of this innovative wound matrix could lead to improved healing rates, reduced healthcare costs, and enhanced quality of life for patients suffering from these difficult-to-treat pressure ulcers.Methods:A case series analysis is being conducted on a cohort of patients with pressure ulcers around the sacrum and ischium that also have tunneling and undermining. These patients receive Miro3D applications as part of their wound management regimen. Data on the number of product applications and wound healing outcomes, including complete healing and ongoing status, is being collected.Results:Two out of three cases have achieved complete healing following one or two applications of Miro3D. These wounds, which had tunneling and undermining of at least 2cm, had been present for two months and seven months, respectively, prior to the first application of Miro3D. One case is still ongoing, with only one Miro3D application administered so far to a wound that had been present for 11 months. This case involves a sacral and an ischial wound with tunneling and undermining as deep as 7.5cm.Discussion: This case series analysis suggests that using Miro3D, a novel three-dimensional porcine liver wound matrix, can help heal deep wounds with tunneling and undermining. Notable outcomes include complete healing of wounds with minimal Miro3D applications. By continuing to study the use of Miro3D in deep, tunneling and undermining wounds and prioritizing patient-centered care, healthcare providers can strive to maximize the potential of this innovative solution in wound healing and enhance patients' quality of life. The successful implementation of this completely unique advanced wound matrix could lead to significant improvements in the management and outcomes of complex pressure ulcers.References: