The Use of Near-Infrared Spectroscopy Imaging in Patients with Peripheral Arterial Disease

Introduction: Peripheral arterial disease (PAD) affects over 200 million people globally, including 8.5 million in the United States, with annual US management costs reaching $22 billion. PAD, characterized by the stenosis or occlusion of peripheral arteries, leads to compromised blood flow and muscle ischemia. This case series explores the clinical significance of multispectral near-infrared spectroscopy (NIRS) and infrared (IR) thermal imaging in diagnosing and monitoring lower-extremity PAD.Methods:A retrospective case series was conducted involving patients with PAD and control subjects. US FDA 510(k) cleared and Health Canada Approved tri-imaging handheld mobile technology* was used to collect a NIRS, thermal, and a digital image in under 1 second. This device was used to measure skin temperature and tissue oxygenation (StO2). Patient demographics, clinical characteristics, and NIRS findings were collected and analyzed.Results:NIRS imaging provided valuable insights into tissue oxygenation levels, potentially aiding in assessing treatment effectiveness and preventing the deterioration of patients with PAD. Regional foot perfusion imaging showed promise in predicting wound healing success.Discussion: NIRS imaging shows promise in evaluating treatment effectiveness and monitoring PAD progression, potentially reducing persistent ulceration and unnecessary amputations. Early diagnosis and assessment using NIRS could prevent complications and improve patient outcomes by ensuring timely vascular evaluations.References: