Topical Agents

Original Research
Efficacy and Safety of a Hyaluronic Acid–Containing Cream in the Treatment of Chronic, Venous, or Mixed-Origin Leg Ulcers: A Prospective, Multicenter Randomized Controlled Trial
10/05/2021
This study compared the efficacy and safety of topical application of a hyaluronic acid cream vs a neutral comparator (identical cream without HA) in treating subjects with chronic leg ulcers of vascular origin.
This study compared the efficacy and safety of topical application of a hyaluronic acid cream vs a neutral comparator (identical cream without HA) in treating subjects with chronic leg ulcers of vascular origin.
This study compared the efficacy...
10/05/2021
Wounds
Original Research
Efficacy and Safety of a Hyaluronic Acid-Containing Gauze Pad in the Treatment of Chronic Venous or Mixed-Origin Leg Ulcers: A Prospective, Multicenter, Randomized Controlled Trial
06/07/2021
This study compared an HA-impregnated gauze pad with a gauze pad without HA.
This study compared an HA-impregnated gauze pad with a gauze pad without HA.
This study compared an...
06/07/2021
Wounds
Topical Products for the Protection of Periwound Skin: A Scoping Review
06/18/2020
The objective of this scoping review is to map out topical products that have been implemented and evaluated for either the protection or treatment of injuries caused by exudate or the use of adhesives or therapeutic dressings on the...
The objective of this scoping review is to map out topical products that have been implemented and evaluated for either the protection or treatment of injuries caused by exudate or the use of adhesives or therapeutic dressings on the...
The objective of this scoping...
06/18/2020
Wounds
Clinical Cases
Health Care Resource Utilization of Patients With Stage 3 and 4 PUs and DFUs Treated Early With CCO
11/13/2019
This study estimates health care resource utilization in the early initiation of clostridial collagenase ointment vs late initiation of clostridial collagenase ointment in stage 3 and 4 pressure ulcers and diabetic foot ulcers in the United...
This study estimates health care resource utilization in the early initiation of clostridial collagenase ointment vs late initiation of clostridial collagenase ointment in stage 3 and 4 pressure ulcers and diabetic foot ulcers in the United...
This study estimates health care...
11/13/2019
Wounds
Clinical Cases
Using a Topical Oxygen Delivery System Over Tissue-based Therapy to Accelerate Wound Healing
11/08/2019
The authors evaluated the effects of a topical oxygen delivery system (TODS) on diabetic foot ulcers (DFUs) undergoing treatment with tissue-based therapy for wound healing.
The authors evaluated the effects of a topical oxygen delivery system (TODS) on diabetic foot ulcers (DFUs) undergoing treatment with tissue-based therapy for wound healing.
The authors evaluated the...
11/08/2019
Wounds
Original Research
Efficacy and Safety of 4% Hibiscus rosa-sinensis Leaf Extract Ointment as an Adjunct Treatment to Compression Stockings on the Closure of Venous Leg Ulcers: A Pilot Study
09/01/2019
The authors evaluate the efficacy and safety of 4% gumamela leaf extract ointment in the closure of VLUs among patients seen in a dermatology outpatient department in the Philippines.
The authors evaluate the efficacy and safety of 4% gumamela leaf extract ointment in the closure of VLUs among patients seen in a dermatology outpatient department in the Philippines.
The authors evaluate the...
09/01/2019
Wounds
Evidence Corner
Topical Burn Wound Management
08/01/2019
Laura Bolton
This month’s Evidence Corner describes 2 recent reviews comparing the effects of topical antiseptics or honey with 1% silver sulfadiazine cream on burn wound healing and infections. 
This month’s Evidence Corner describes 2 recent reviews comparing the effects of topical antiseptics or honey with 1% silver sulfadiazine cream on burn wound healing and infections. 
This month’s Evidence Corner...
08/01/2019
Wounds
Laboratory Research
A Pilot Study of the Antibacterial Activity of Topical Fatty Acids
06/06/2019
In this video, Dr. Gibson describes 3 experiments that sought to determine if an oil-based product could reduce viable Staphylococcus aureus in a porcine skin wound model, which was exhibited as a poster at the 2019 Symposium on Advanced...
In this video, Dr. Gibson describes 3 experiments that sought to determine if an oil-based product could reduce viable Staphylococcus aureus in a porcine skin wound model, which was exhibited as a poster at the 2019 Symposium on Advanced...
In this video, Dr. Gibson...
06/06/2019
Wounds
Review
A Comprehensive Review of Local Pharmacologic Therapy for Pyoderma Gangrenosum
06/01/2019
This literature review assesses all available local therapies in order to summarize the use and reported efficaciousness of the broad range of local treatments available for PG.
This literature review assesses all available local therapies in order to summarize the use and reported efficaciousness of the broad range of local treatments available for PG.
This literature review assesses...
06/01/2019
Wounds
Laboratory Research
Demonstration of AC5 Topical Gel in Porcine Full-thickness Surgical Wound Models
04/23/2019
This video discusses and demonstrates a recently FDA-cleared topical gel in porcine full-thickness surgical wound models.
This video discusses and demonstrates a recently FDA-cleared topical gel in porcine full-thickness surgical wound models.
This video discusses and...
04/23/2019
Wounds

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