Topical Agents

Original Research

Efficacy and Safety of a Hyaluronic Acid–Containing Cream in the Treatment of Chronic, Venous, or Mixed-Origin Leg Ulcers: A Prospective, Multicenter Randomized Controlled Trial

10/05/2021

Jacek Mikosinski

Anna Di Landro

Karolina Kasztalska-Kazmierczak

Emilie Soriano

Carol Caverzasio

Daniela Binelli

Bruno Falissard

Olivier Dereure

This study compared the efficacy and safety of topical application of a hyaluronic acid cream vs a neutral comparator (identical cream without HA) in treating subjects with chronic leg ulcers of vascular origin.

This study compared the efficacy...

10/05/2021

Wounds

Original Research

Efficacy and Safety of a Hyaluronic Acid-Containing Gauze Pad in the Treatment of Chronic Venous or Mixed-Origin Leg Ulcers: A Prospective, Multicenter, Randomized Controlled Trial

06/07/2021

Jacek Mikosinski

Anna Di Landro

Krzysztofa Łuczak-Szymerska

Emilie Soriano

Carol Caverzasio

Daniela Binelli

Bruno Falissard

Olivier Dereure

This study compared an HA-impregnated gauze pad with a gauze pad without HA.

This study compared an...

06/07/2021

Wounds

Topical Products for the Protection of Periwound Skin: A Scoping Review

06/18/2020

Giovanny Andrés Perez Jaimes

Wilmer Julián Rueda Barrera

Leidy Johanna Rueda Díaz

The objective of this scoping review is to map out topical products that have been implemented and evaluated for either the protection or treatment of injuries caused by exudate or the use of adhesives or therapeutic dressings on the...

The objective of this scoping...

06/18/2020

Wounds

Clinical Cases

Health Care Resource Utilization of Patients With Stage 3 and 4 PUs and DFUs Treated Early With CCO

11/13/2019

This study estimates health care resource utilization in the early initiation of clostridial collagenase ointment vs late initiation of clostridial collagenase ointment in stage 3 and 4 pressure ulcers and diabetic foot ulcers in the United...

This study estimates health care...

11/13/2019

Wounds

Clinical Cases

Using a Topical Oxygen Delivery System Over Tissue-based Therapy to Accelerate Wound Healing

11/08/2019

Windy Cole

The authors evaluated the effects of a topical oxygen delivery system (TODS) on diabetic foot ulcers (DFUs) undergoing treatment with tissue-based therapy for wound healing.

The authors evaluated the...

11/08/2019

Wounds

Original Research

Efficacy and Safety of 4% Hibiscus rosa-sinensis Leaf Extract Ointment as an Adjunct Treatment to Compression Stockings on the Closure of Venous Leg Ulcers: A Pilot Study

09/01/2019

Martha Joy Maralit Bruan

Elizabeth Amelia Tianco

The authors evaluate the efficacy and safety of 4% gumamela leaf extract ointment in the closure of VLUs among patients seen in a dermatology outpatient department in the Philippines.

The authors evaluate the...

09/01/2019

Wounds

Evidence Corner

Topical Burn Wound Management

08/01/2019

Laura Bolton

This month’s Evidence Corner describes 2 recent reviews comparing the effects of topical antiseptics or honey with 1% silver sulfadiazine cream on burn wound healing and infections.

This month’s Evidence Corner...

08/01/2019

Wounds

Laboratory Research

A Pilot Study of the Antibacterial Activity of Topical Fatty Acids

06/06/2019

In this video, Dr. Gibson describes 3 experiments that sought to determine if an oil-based product could reduce viable Staphylococcus aureus in a porcine skin wound model, which was exhibited as a poster at the 2019 Symposium on Advanced...

In this video, Dr. Gibson...

06/06/2019

Wounds

Review

A Comprehensive Review of Local Pharmacologic Therapy for Pyoderma Gangrenosum

06/01/2019

David Baltazar

Carter Haag

Angela S. Gupta

Angelo V. Marzano

Alex G. Ortega Loayza

This literature review assesses all available local therapies in order to summarize the use and reported efficaciousness of the broad range of local treatments available for PG.

This literature review assesses...

06/01/2019

Wounds

Laboratory Research

Demonstration of AC5 Topical Gel in Porcine Full-thickness Surgical Wound Models

04/23/2019

This video discusses and demonstrates a recently FDA-cleared topical gel in porcine full-thickness surgical wound models.

This video discusses and...

04/23/2019

Wounds