biomarkers

Blood Test Predicts Treatment Response for NETs

06/27/2016

JCP Editors

A study presented at the 2016 Society of Nuclear Medicine and Molecular Imaging Annual Meeting (June 11-15; San Diego, CA [SNMMI]) has found that a novel investigative blood test could predict how patients with...

A...

06/27/2016

Journal of Clinical Pathways

New Treatment Improves Response in ALK-Positive NSCLC

06/14/2016

JCP Editors

Patients with ALK-positive non-small cell lung cancer (NSCLC) whose disease has progressed while on crizotinib (CRZ) may experience improved response rates when treated with the investigational tyrosine kinase...

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06/14/2016

Journal of Clinical Pathways

Biomarker-Guided Therapy Leads to Improved Response in Phase 1 Trials

06/05/2016

JCP Editors

Using biomarkers to guide treatment in clinical trials may yield higher response rates than similar drugs not guided by biomarkers, according to an abstract presented at the American Society of Clinical Oncology...

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06/05/2016

Journal of Clinical Pathways

Research in Review

Integrative Genomic Approach to Cancer Care Leads to More Actionable Variants

06/02/2016

JCP Editors

A genomic approach developed and tested by scientists at the Icahn School of Medicine at Mount Sinai (New York City, NY) helped support decision-making and led to therapeutic recommendations for a group of patients...

A...

06/02/2016

Journal of Clinical Pathways

Research in Review

Breast Cancer Biomarker of Chemotherapy Resistance Identified

05/26/2016

JCP Editors

Expression of methylation-controlled J protein (MCJ) may be an indicator of successful outcomes and reduced risk of relapse in patients with breast cancer, according to a recent study. Chemotherapy is a key part of...

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05/26/2016

Journal of Clinical Pathways

Research in Review

Novel Biomarker Predicts Treatment Response in NSCLC

05/19/2016

JCP Editors

A study of SMARCA/BRG1 expression in patients with non-small cell lung (NSCLC) cancer has found that it is a significant indicator of prognosis and a novel predictive biomarker for increased sensitivity to...

A...

05/19/2016

Journal of Clinical Pathways

Research in Review

Biomarkers Predict Cetuximab Performance in Metastatic Colorectal Cancer

05/17/2016

JCP Editors

Treatment with cetuximab is most effective for patients with KRAS wild-type colorectal cancers carrying a specific genetic marker, according to a recent study. In an article published in Clinical Cancer Research,...

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05/17/2016

Journal of Clinical Pathways

Research in Review

HPV-16 Associated with Better Overall Survival in Patients With Head and Neck Cancer

03/31/2016

JCP Editors

The presence of human papillomavirus-16 (HPV-16) is associated with higher rates of overall survival in patients with head and neck squamous cell carcinoma (HNSC), suggesting it may be a more effective prognostic...

The...

03/31/2016

Journal of Clinical Pathways

Research in Review

Report Outlines the Path to Improving Biomarker Tests for Targeted Therapies

03/21/2016

JCP Editors

Biomarker tests are not being adequately used in clinical practice due to a lack of common evidentiary standards for regulatory, reimbursement, and clinical decisions regarding their use, according to a report by the...

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03/21/2016

Journal of Clinical Pathways

Original Contribution

Periprocedural Myocardial Injury and Long-Term Clinical Outcome in Patients Undergoing Percutaneous Coronary Interventions of Coronary Chronic Total Occlusion

03/15/2016

Luigi Di Serafino, MD, PhD^1,2; Francesco Borgia, MD, PhD^3,4; Joren Maeremans^5,6; Stylianos A. Pyxaras, MD⁷; Bernard De Bruyne, MD, PhD¹; William Wijns, MD, PhD¹; Guy R. Heyndrickx, MD, PhD¹; Jo Dens, MD, PhD⁵; Carlo Di Mario, MD, PhD⁴; Emanuele Barbato, MD, PhD^1,3

Luigi Di Serafino, MD, PhD1,2; Franc...

This study examines the prognostic implication of periprocedural myocardial injury (PMI) in chronic total occlusion PCI.

This study examines the...

03/15/2016

Journal of Invasive Cardiology