Antiplatelet therapy

Original Contribution

Toward Personalized DAPT: Is There an Inter-Manufacturer Difference in Generic Clopidogrel Response?

11/23/2022

Sylvie Hall, PharmD, MPH¹; Yuhe Xia, MS²; Hamza Ahmed, BA³;
Daniela Iskhakov, PA-C⁴; Frederick Feit, MD⁴; Carlos L. Alviar, MD⁴;
Jeffrey S. Berger, MD, MS⁴; Norma Keller, MD⁴; Sripal Bangalore, MD, MHA⁴

Sylvie Hall, PharmD, MPH1; Yuhe Xia,...

This quality-improvement project included 515 adult patients receiving clopidogrel for ACS or ischemic heart disease and referred for coronary angiography/percutaneous coronary intervention. The project was divided into 2 phases: (1)...

This quality-improvement project...

11/23/2022

Journal of Invasive Cardiology

The Movement to Short-Infusion Tirofiban in the Cath Lab: the Next Leap in Practice Change

03/01/2018

Cath Lab Digest talks to J. Brent Muhlestein, MD, FAHA, FACC,

Co-Director of Cardiology Research, Intermountain Health Care and

Intermountain Medical Center, Salt Lake City, Utah; Professor of Medicine, University of Utah, Salt Lake City, Utah.

Cath Lab Digest talks to J. Brent Muh...

If patients are not already on dual antiplatelet therapy when they come in, achieving that status is going to take time and there is going to be a window in which they are not protected. One of the advantages of the short-term infusion of...

If patients are not already on...

03/01/2018

Cath Lab Digest

Original Contribution

Impact of Switching From Prasugrel to Clopidogrel Shortly After a Percutaneous Coronary Intervention Without a Loading Dose of Clopidogrel

09/15/2015

Eddy Mizrahi, MD¹; Ramya Smitha Suryadevara, MD¹; Kulpreet Barn, MD¹; Gouthami Boga, MD¹; Mian Muhammad Ali Akram, MD¹; Ibrahim Ismail-Sayed, MD²; Yvette M. Henry, PhD³; Melissa A. Troup, MHSA³; Peter B. Berger, MD⁴

Eddy Mizrahi, MD1; Ramya Smitha Sury...

The authors present a retrospective analysis to determine the safety and efficacy of administering prasugrel at the time of percutaneous coronary intervention (PCI), and switching to clopidogrel, without reloading.

The authors present a...

09/15/2015

Journal of Invasive Cardiology

Delayed Clopidogrel Transit During Myocardial Infarction Evident on Angiography

04/29/2015

Joanna Ghobrial, MD, MS; C. Michael Gibson, MS, MD; Duane S. Pinto, MD, MPH

Joanna Ghobrial, MD, MS; C. Michael ...

We describe the case of a patient with NSTEMI where oral clopidogrel loading prior to PCI was directly visualized on angiography, implying a very low likelihood of adequate absorption or antiplatelet effect. This observation raises the...

We describe the case of a...

04/29/2015

Journal of Invasive Cardiology

Clinical Editor's Corner

Conversations in Cardiology: What to Do if Your Patient Can’t Take Aspirin After Stenting

10/15/2014

Morton Kern, MD

“I just put two drug-eluting stents into a native vessel and a distal graft anastomosis in a patient who is already on clopidogrel AND who has an aspirin allergy that cannot be touched or addressed. What additional drug, if any, would you...

“I just put two drug-eluting...

10/15/2014

Cath Lab Digest

Commentary

Optimal Antiplatelet Therapy: Lessons Learned from PCI Applicable to PAD and PPI

09/05/2008

David Alllie, MD

Patti et al. have further added to the mounting evidence that optimal antiplatelet therapy translates to clinical benefits in PCI by reporting the results of the ARMYDA-2 trial, which was a prospective, randomized trial between a pretreatment...

Patti et al. have further added...

09/05/2008

Vascular Disease Management

Original Contribution

Optimal Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention: New Insights From the ARMYDA-2 Study

09/05/2008

Germano Di Sciascio, MD
UCBM, Rome, Italy

Germano Di Sciascio, MD UCBM, Rome, I...

Percutaneous coronary intervention (PCI) with stenting has been shown to enhance platelet aggregation. Accordingly, optimization of antiplatelet therapy has a crucial role in patients undergoing percutaneous revascularization and even more...

Percutaneous coronary...

09/05/2008

Vascular Disease Management