Dermatology

Reducing Biofilm in the Wound Bed of Deep Dermal Wounds Using a Novel Non-Biologic Topical Liquid Agent

Chronic wounds account for significant patient morbidity and has a major economic impact on the cost of healthcare. There are many causes for wounds to stall in the inflammatory phase, th...

05/26/2022

Use of Negative Pressure Wound Therapy With Instillation to Cleanse Lower Extremity Wounds

Introduction: Use of negative pressure wound therapy (NPWT) with instillation and dwell time (NPWTi-d*) to deliver, dwell, and remove topical wound solutions from the wound bed can assist...

05/26/2022

The use of implantable acellular fish skin to augment lower extremity reconstruction

Introduction: Various allografts and xenograft have become more popular as implants to aid in tissue support. Limb salvage has seen an increase use of implants including, amniotic and der...

05/26/2022

Biologic agent sparing potential of fish skin grafts in treatment resistant pyoderma gangrenosum: a case study

Introduction: Pyoderma gangrenosum (PG) is an ulcerative skin disorder that is caused by neutrophil dysfunction, genetic function, and systemic inflammation, best known as a complication ...

05/26/2022

Autologous Treatment in Limb Threatening Diabetic Foot Wounds: A Trifecta of Autologous Fibrin, Leukocytes and Platelets in Fifteen Patients

Objectives: The investigators of this study provide an analysis of fifteen patients treated with an autologous patch consisting of fibrin, leukocytes and platelets. These patients have fa...

05/26/2022

The Effect of Timing of Instillation Therapy on Outcomes and Costs for Patients Receiving Negative Pressure Wound Therapy

Introduction: Negative pressure wound therapy with instillation and dwell time (NPWTi-d) involves the periodic instillation of topical solution into a wound followed by the application of...

05/26/2022

A Comparative Effectiveness Research Study of a Bilayered Living Cellular Construct and a Viable Cryopreserved Placental Membrane for Use in Pressure Injuries

OBJECTIVES: Using real-world data (RWD) we conducted a comparative effectiveness analysis of a bilayered living cellular construct (BLCC)(a) versus a viable cryopreserved placental membra...

05/26/2022

A Clinical Tool to Predict Severe Pain During Wound Dressing Changes

Introduction: Dressing changes cause severe pain (i.e., 8 to 10 on a 10-poiont scale) for approximately one-third (36%) of patients with open skin wounds. No tool exists that allows nurse...

05/26/2022

Dermal _-catenin is required for SHH driven hair follicle neogenesis.

Hair follicle neogenesis (HFN) occurs in adult skin upon large skin excisions in mice, serving as a rare regenerative model in mammalian wound healing. Nonetheless, wound healing typicall...

08/19/2021