Abstracts

Claudin-16, its clinical and prognostic value in colorectal cancer

Background Claudin-16, also known as CLDN-16 or paracellin-1, plays a major role in tight junction-specific occlusion of the intercellular space, through calcium-indepen...

06/27/2022

Chemotherapy dosing for cycle 1 in metastatic pancreatic cancer in routine practice

Background Pancreatic cancer is the third most frequent type of gastrointestinal cancer in Europe and the fourth leading cause of death. Its diagnosis is usually late, a...

06/27/2022

Is preoperative chemosensitivity associated with improved outcomes in locally advanced gastric cancer?

Background Perioperative chemotherapy (PCT) is the standard of care for locally advanced gastric cancer (LAGC) in western countries. Less than 60% of patients complete t...

06/27/2022

Efficacy and safety of anti-PD-1 agents in patients with dMMR metastatic solid tumours: A retrospective, real-world study

Background Immune checkpoint inhibitors (ICIs) have been a revolution in the treatment of solid tumours with a significant increase in overall survival rates. High micro...

Brage E. Terán ;

Tocino R. Vidal ;

Gutiérrez A. López ;

Pérez L. Figuero ;

Sánchez E. Fonseca ;

Gómez A. Moreno ;

Mejorada R. Lozano ;

06/27/2022

Liver transplantation for hilar cholangiocarcinoma: A systematic review and meta-analysis

Background Both liver transplantation and surgical resection are available for selected patients with hilar cholangiocarcinoma. However, the effect of liver transplantat...

06/27/2022

Serum levels of HMGB1 might have a predictive role for neoadjuvant radiotherapy combined with chemotherapy in rectal cancer patients

Background The standard treatment for locally advanced rectal cancer (LARC), is neoadjuvant concurrent chemoradiation (nCCRT), after which total mesorectal excision is p...

06/27/2022

Decreased overall survival after resection for colorectal cancer outside working hours

Background Colorectal cancer (CRC) is one of the most common malignant neoplasms worldwide. Emergency presentations occur in up to 30 % of CRC cases. Studies describe a ...

06/27/2022

FOLFIRI as third- or later-line treatment for advanced biliary tract cancer in Northern Thailand

Background The combination of gemcitabine and cisplatin, and FOLFOX (fluorouracil and oxaliplatin) are recognized as the standard first- and second-line chemotherapy reg...

06/27/2022

Fluoropyrimidine- and irinotecan-induced toxicity profile associated with mutations in DPYD and UGT1A1 genes

Background Fluoropyrimidines are a mainstay in the treatment of gastrointestinal tumours (GIT), although they can sometimes produce severe toxicity, usually related to p...

Brage E. Terán ;

Tocino R. Vidal ;

García B. Cigarral ;

Sánchez E. Fonseca ;

Martín M. Navarro ;

Jung D. Heredero ;

Berrocal B. García ;

Jiménez M. Navalón ;

06/27/2022

A scoring model to predict the clinical outcome of self-expandable metal stents in patients with colorectal obstruction due to extracolonic malignancy

Background Self-expandable metal stents (SEMS) can be applied to relieve colorectal obstruction secondary to extracolonic malignancy (ECM), but data regarding this issue...

06/27/2022