Background
Adjuvant chemotherapy is recommended in patients with stage II colon cancer with high-risk features. The objective of our study is to assess survival benefits...
Background
Standard first-line treatment of metastatic colorectal cancer (mCRC) is combination chemotherapy with the addition of a biological agent. Several randomized c...
Background
Colorectal cancer (CCR) is the third most common and the second most deadly cancer with 1.9 million new diagnoses worldwide in 2020. COVID-19 pandemic placed ...
Background
For many years, adjuvant fluoropyrimidine-based chemotherapy for 6 months has been the standard of care in stage II-III colon cancer with an improved overall ...
Background
Pancreatic cancer is the third leading cause of cancer death in the USA with current standard of care treatments that have moderate toxicity and median overal...
Background
Anal squamous cell carcinoma (SCC) is an uncommon malignancy of all cancers of the lower intestinal tract. Concurrent chemoradiation (ChRT) with 5-fluorouraci...
Background
Gastric cancer (GC) is one of the most common malignancies worldwide. Multidisciplinary strategies including chemotherapy, radiotherapy and surgical resection...
Background
The tumor differentiation grade has been shown by several studies to be a stage-independent prognostic factor in colorectal cancer (CRC) 1. It is a factor tha...
Background
Currently, the median age of PC patients is about 70 years. By 2030 nearly 70% of PC are expected to be diagnosed in the elderly. These patients are poorly re...
Background
Protein tyrosine phosphatase kappa (PTPRK) is a phosphatase which is recognised as a tumour suppressor. PTPRK can promote the internalization of ZNRF3 by deph...