Dennis P. Orgill, MD, PhD

The Outcomes associated with a pressure injury prevention prone positioning Protocol
on Pressure Injuries in SARS-CoV-2 infected Acute Respiratory Distress Syndrome patients:
a multi-center observational study

Purpose. During the COVID-19, patients were placed in a prone position. The purpose of this study was to evaluate the effectiveness of a certified wound and skin care nurse leading the pr...

Charles M. Zelen , DPM, FACFAS;

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

Lawrence A. DiDomenico , DPM, FACFAS;

Marissa J. Carter , PhD;

Paul M. Glat , MD, FACS;

Robert D. Galiano , MD;

Connie Johnson , MSN, RN, WCC, OMS;

05/26/2022

A Multicenter Randomized Controlled Clinical Trial Evaluating Two Application
Regimens of Dehydrated Human Amniotic Membrane and Standard of Care vs
Standard of Care Alone in the Treatment of Venous Leg Ulcers

IntroductionVenous leg ulcerations(VLUs) frequently represent a significant clinical challenge. Dehydrated human amnion and chorion allografts have shown great promise in the treatment of...

Thomas E. Serena , MD, FACS, FACHM, MAPWCA;

Robert D. Galiano , MD;

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

Lawrence A. DiDomenico , DPM, FACFAS;

Marissa J. Carter , PhD;

Paul M. Glat , MD, FACS;

William W. Li , MD;

05/26/2022

Functional Properties of a Purified Reconstituted Bilayer Matrix Design Support Natural Wound Healing Activities

Background: Advanced biomaterial engineering has produced unique wound care matrices using various tissue sources and processing methods. Source and process may impact the ability of the ...

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

Paul M. Glat , MD, FACS;

Robert D. Galiano , MD;

Marco Mehr , MSc;

Charles M. Zelen , DPM, FACFAS;

08/19/2021

Use of a Purified Reconstituted Bilayer Matrix in the Management of Chronic Diabetic Foot Ulcers Improves Patient Outcomes vs Standard of Care – Results of a Prospective Randomized Controlled Multi-Center Clinical Trial

Introduction In a previous series of 10 patients the authors evaluated a unique Purified Reconstituted Bilayer Matrix(PRBM) and found the material safe and efficacious in the treatment o...

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Robert D. Galiano , MD;

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

Lawrence A. DiDomenico , DPM, FACFAS;

Marissa J. Carter , PhD;

Paul M. Glat , MD, FACS;

08/19/2021

A Randomized Controlled Trial to Evaluate the Treatment of Diabetic Foot Ulcers with a Novel Autologous Heterogeneous Skin Construct

Introduction and Objective: A novel autologous heterogeneous skin construct (AHSC) has been developed for the repair and replacement of skin. A pilot study demonstrated the ability of AHS...

Robert D. Galiano , MD;

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Paul M. Glat , MD, FACS;

08/19/2021

A Randomized Controlled Trial to Evaluate the Treatment of Venous Leg Ulcers with a Novel Autologous Heterogeneous Skin Construct

Introduction and Objective: A novel autologous heterogeneous skin construct (AHSC) has been developed for the repair and replacement of skin. A pilot study demonstrated the ability of AHS...

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Paul M. Glat , MD, FACS;

Robert D. Galiano , MD;

08/19/2021

Use of a Purified Reconstituted Bilayer Matrix in the Management of Non-Healing Diabetic Foot Ulcers: A Prospective Randomized Controlled Multicenter Clinical Trial

Patients with diabetic foot ulcers (DFUs), in particular when unresponsive to standard wound care, face serious risks of severe complications, including infection and amputation. The mana...

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

Marissa J. Carter , PhD;

Lawrence A. DiDomenico , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Robert D. Galiano , MD;

01/28/2021

Mechanism of Action of a Novel Advanced Wound Care Matrix

The authors recently described the safety and performance of a novel advanced wound care matrix (AWCM) in an IRB-approved retrospective study with 10 diabetic foot ulcer patients. This ma...

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

Robert D. Galiano , MD;

Paul M. Glat , MD, FACS;

12/06/2019

Pilot Study Assessing Novel Autologous Homologous Skin Construct Treatment of Nonhealing Diabetic Foot Wounds

Introduction: Diabetic foot ulcers (DFUs) are a significant burden on the worldwide health-care system. These chronic lower extremity wounds are often refractory to standard of care and c...

Robert D. Galiano , MD;

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Paul M. Glat , MD, FACS;

11/04/2019

A Retrospective Case Series to Evaluate the Safety and Efficacy of a Novel Advanced Wound Care Matrix in the Management of Nonhealing Diabetic Foot Ulcers

Introduction: Advanced tissue matrices have shown promise for treating diabetic wounds and other soft tissue defects. Recent advancements in technology have led to the introduction of a n...

Marissa J. Carter , PhD;

Paul M. Glat , MD, FACS;

Robert D. Galiano , MD;

Charles M. Zelen , DPM, FACFAS;

David G. Armstrong , DPM, MD, PhD, MSc;

Dennis P. Orgill , MD, PhD;

Jarrod P. Kaufman , MD;

11/04/2019