comparative-effectiveness research

News

Comparative Effectiveness of Digital Breast Tomosynthesis vs Digital Mammography in Community Practice

09/03/2020

Journal of Clinical Pathways

Research in Review

High-Dose Treatment for Acute Lymphoblastic Leukemia Safe, Improves Survival

04/29/2016

JCP Editors

Initial results from a clinical trial have shown that high-dose methotrexate may be superior to standard, low-dose regimens without increasing toxicity for children and young adults with high-risk B-acute...

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04/29/2016

Journal of Clinical Pathways

Research in Review

Neratinib Delays Recurrence With Fewer Metastases in Patients With Breast Cancer

04/29/2016

JCP Editors

Results from a phase 2 clinical trial showed that combination neratinib and paclitaxel treatment better managed central nervous system progression versus trastuzumab and paclitaxel in patients with ERBB2-positive...

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04/29/2016

Journal of Clinical Pathways

Research in Review

Standard Therapy Only Used in Half of US Patients With Rectal Cancer

04/20/2016

JCP Editors

Despite being widely accepted as the standard of care for locally advanced rectal cancer, neoadjuvant chemoradiation (NACRT) is only used in about half of US patients with the disease, according to a recent...

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04/20/2016

Journal of Clinical Pathways

Research in Review

Enzalutamide Improves Survival Over Bicalutamide in Castration-Resistant Prostate Cancer

02/02/2016

JCP Editors

Treatment with enzalutamide rather than bicalutamide for nonmetastatic or metastatic castration-resistant prostate cancer (CRPC) improves survival, according to results of a phase 2 clinical trial. CRPC occurs when...

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02/02/2016

Journal of Clinical Pathways

Viewpoint

Overcoming the Political and Economic Roadblocks Stopping Effective Comparative Drug Evaluation

12/14/2015

Roger Longman, MA

Transparent comparative evaluations are necessary for determining the relative value of drugs. But, in part because of the resistance of drug companies and payers, stakeholders are finding other tools to help...

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12/14/2015

Journal of Clinical Pathways