personalized medicine

Research in Review

Genetic Variant of Rectal Cancer Predicts Prognosis, Treatment Response

07/25/2016

JCP Editors

DNA mismatch repair (dMMR) deficiency rectal cancer is associated with excellent prognosis and pathologic response with current therapeutic options and surgical procedures, according to research published in the...

DNA...

07/25/2016

Journal of Clinical Pathways

Research in Review

Better Screening May Eliminate the Need for Lung Cancer Surgery in Some Patients

07/22/2016

JCP Editors

A new, large-scale study has lent support to the recommendation that nonsolid nodules identified by CT (computed tomography) scans can be managed with annual screening rather than with invasive biopsies or...

A new,...

07/22/2016

Journal of Clinical Pathways

Research in Review

Expectant Management for Prostate Cancer Underutilized at Community Centers

07/15/2016

JCP Editors

A retrospective analysis of hospital trends has shown that the likelihood of receiving expectant management for low-risk prostate cancer was significantly lower in men evaluated at community centers compared with...

A...

07/15/2016

Journal of Clinical Pathways

Research in Review

Anthracycline-based Regimens Improve Survival in Elderly Patients With Lymphoma

07/13/2016

JCP Editors

Findings from a single-center analysis have shown that anthracycline-based therapies may produce better outcomes in patients age 80 years and older with diffuse large B-cell lymphoma (DLBCL), supporting data reported...

...

07/13/2016

Journal of Clinical Pathways

Research in Review

Psychosocial Data and Multidisciplinary Input Aid Cancer Treatment Decision-Making

07/08/2016

JCP Editors

Patient psychosocial information and input from certain experts in multidisciplinary tumor boards (MTBs) helps teams to reach decisions about cancer care more easily, according to an article published in Annals of...

...

07/08/2016

Journal of Clinical Pathways

Research in Review

Breast Cancer Treatment May Lead to Functional Decline or Death in Elderly Patients

07/01/2016

JCP Editors

Many older women diagnosed with nonmetastatic breast cancer may experience functional decline or death within 12 months of breast cancer treatment initiation, but the Vulnerable Elders Survey (VES-12) may help to...

Many...

07/01/2016

Journal of Clinical Pathways

Clinical Pathways GPS

Beyond Medication Class: How Specific Should the Clinical Pathway Get?

06/20/2016

Richard G Stefanacci, DO, MGH, MBA, AGSF, CMD–Column Editor

Taha Khan, PharmD, RPh

Aspects of a medication beyond the chemical composition can have an impact on patient outcomes. Consideration of these aspects when developing clinical pathways may result in particular formulations or delivery...

...

06/20/2016

Journal of Clinical Pathways

Research in Review

Formula for Optimal Radiosurgery Dose Developed to Guide Brain Metastasis Treatment

06/15/2016

JCP Editors

Researchers from the department of radiation oncology at the VU University Medical Center in Amsterdam, the Netherlands, have proposed a novel formula for the optimization of radiosurgery dose for any given lesion...

...

06/15/2016

Journal of Clinical Pathways

Web Application Improves Survival and Follow-up for Patients With Lung Cancer

06/10/2016

JCP Editors

Using a web-based application to guide follow-up for patients with advanced lung cancer after they have received initial therapy may improve survival, according to a study presented at the 2016 American Society of...

Using...

06/10/2016

Journal of Clinical Pathways

Biomarker-Guided Therapy Leads to Improved Response in Phase 1 Trials

06/05/2016

JCP Editors

Using biomarkers to guide treatment in clinical trials may yield higher response rates than similar drugs not guided by biomarkers, according to an abstract presented at the American Society of Clinical Oncology...

...

06/05/2016

Journal of Clinical Pathways