personalized medicine

Research in Review

Microbiome Signature Helps Predict Prostate Cancer

06/01/2017

JCP Editors

Transcriptome sequencing that identifies pathogens in prostate cancer biopsies can be used as a signature for disease detection, according to research presented at the 2017 ASCO Annual Meeting (June 2-6, 2017;...

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06/01/2017

Journal of Clinical Pathways

Research in Review

PARP-1 Measurement Guides Treatment Decisions in Ovarian Cancer

05/12/2017

JCP Editors

New research shows that blocking poly (ADP-ribose) polymerase-1 (PARP-1) may have a greater impact than restoring BRCA1 for the treatment of ovarian cancer, according to research presented at the 2017 American...

New...

05/12/2017

Journal of Clinical Pathways

Research in Review

Dose-Escalated Therapy May Be Curative for Multiple B-Cell Malignancies

04/26/2017

JCP Editors

Dose-escalated therapy involving a single agent produced complete and partial responses in patients with different B-cell malignancies. ----- Related Content Maintenance Therapy Effective in Treating Diffuse Large...

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04/26/2017

Journal of Clinical Pathways

Research in Review

Cost-Effectiveness of Early-Stage Breast Cancer Treatment Options Vary Significantly

04/21/2017

JCP Editors

Certain therapy options for early-stage breast cancer have fewer associated complications and are much less expensive than others, according to a study published in the Journal of the National Cancer Institute...

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04/21/2017

Journal of Clinical Pathways

Research in Review

Genomic Analyses Guide Targeted Therapies for Metastatic Cancers

04/07/2017

JCP Editors

High-throughput genomic analyses may improve outcomes in patients with types of metastatic cancer, according to results of a recent trial published in Cancer Discovery (published online April 1, 2017;...

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04/07/2017

Journal of Clinical Pathways

Research in Review

Immune Systems Impact Immunotherapy Effectiveness in Head and Neck Cancer

04/05/2017

JCP Editors

Specific immune cells surrounding tumors may play a crucial role in how patients with head and neck cancer respond to nivolumab immunotherapy, according to research presented at the American Association of Cancer...

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04/05/2017

Journal of Clinical Pathways

Research in Review

Meta-Analysis Reveals Optimal Combination Therapy for Multiple Myeloma

03/24/2017

JCP Editors

A triple-combination treatment strategy is the most effective therapy for patients with relapsed or refractory multiple myeloma, according to a meta-analysis published in the Journal of Clinical Oncology (published...

A...

03/24/2017

Journal of Clinical Pathways

Research in Review

Multikinase Inhibitors Ineffective in Treating RET-Rearranged NSCLC

03/17/2017

JCP Editors

Overall response rate (ORR) is low for patients with non-small cell lung cancer (NSCLC) with RET rearrangements after targeted therapy, according to research published in the Journal of Clinical Oncology (March 13,...

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03/17/2017

Journal of Clinical Pathways

Research in Review

Body Composition Impacts Chemo Toxicity for Patients With Breast Cancer

03/07/2017

JCP Editors

Using body composition metrics to determine dosage of anthracyclines-taxane based chemotherapy for patients with breast cancer can reduce treatment-related toxicity, according to a study published in Clinical Cancer...

Using...

03/07/2017

Journal of Clinical Pathways

Research in Review

Varying Toxicities Between EGFR-TKIs for Treatment of NSCLC

12/29/2016

JCP Editors

Varying degrees of toxicity risks between different epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) can help inform treatment decisions for individual patients with non-small cell lung...

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12/29/2016

Journal of Clinical Pathways