precision medicine

Research in Review

HAPs Prevent Treatment Resistance in EGFR+ NSCLC

09/12/2016

JCP Editors

Adding a hypoxia-activated prodrug (HAP) to standard care for epidermal growth factor receptor-positive non-small cell lung cancer may help to delay treatment resistance, according to a study published in PLOS...

Adding...

09/12/2016

Journal of Clinical Pathways

Research in Review

Esophageal Cancer Actually 3 Distinct Diseases

09/09/2016

JCP Editors

A study published in Nature Genetics claims that esophageal cancer may in fact be 3 distinct diseases, which could pave the way for new methods of diagnosis and spur the development of targeted treatment...

A...

09/09/2016

Journal of Clinical Pathways

Research in Review

Vinblastine for Low-Grade Glioma Has Few Side Effects and Comparable Survival

09/09/2016

JCP Editors

Vinblastine monotherapy has similar outcomes and a more favorable toxicity profile compared with current therapies when used in patients with treatment naïve pediatric low-grade glioma (PLGG), according to a study...

...

09/09/2016

Journal of Clinical Pathways

Research in Review

Immunotherapy Plus Chemotherapy Kills More Cancer Cells Than Chemotherapy Alone

09/09/2016

JCP Editors

When chemotherapy alone is used to treat cancer, some dormant cells may survive and become resistant to additional treatment; but, when combined with immunotherapy, the majority of these cells may be destroyed,...

When...

09/09/2016

Journal of Clinical Pathways

Pharma Insights

Clarity Regarding Prostate Cancer Screening, Why Payers Need It Too

09/06/2016

Jeremy Schafer , PharmD, MBA;

Controversy over the lack of a survival benefit associated with early diagnosis of prostate cancer through prostate-specific antigen (PSA) screening has led to uncertainty in the determination of PSA coverage and its...

...

09/06/2016

Journal of Clinical Pathways

Research in Review

Addition of Panobinostat to Multiple Myeloma Care Has Little Economic Impact

09/06/2016

JCP Editors

Adding panobinostat to treatment regimens for multiple myeloma would have a minimal economic impact and could even save the health care system money, claims a study published in the Journal of Managed Care &...

Adding...

09/06/2016

Journal of Clinical Pathways

Editor's Page

A Greater Focus on the Patient

09/06/2016

Winston Wong , PharmD;

One of the core goals of clinical pathways development has always been to make health care more patient-centered. However, a common complaint regarding clinical pathway development is that patients are often left out...

One of...

09/06/2016

Journal of Clinical Pathways

Research in Review

More Docetaxel Cycles May Improve Prostate Cancer Survival

08/30/2016

JCP Editors

A larger number of docetaxel cycles may improve survival among men with metastatic castration-resistant prostate cancer (mCRPC), according to a post-hoc analysis of phase III clinical trial results. Scientists and...

A...

08/30/2016

Journal of Clinical Pathways

Research in Review

70-Gene Signature Aids Breast Cancer Decision-Making

08/30/2016

JCP Editors

The 70-gene signature test may help patients with early-stage breast cancer avoid unneeded chemotherapy, according to the results of a study published in The New England Journal of Medicine. The 70-gene signature...

The...

08/30/2016

Journal of Clinical Pathways

Research in Review

Breast Cancer Genes Associated With Increased Risk of Death

08/27/2016

JCP Editors

Two genes in breast cancer tumors may indicate an increased risk of death, suggests a new study published in Oncotarget. For the study, researchers led by Paul H Huang,  looked at breast cancer cells positive...

Two...

08/27/2016

Journal of Clinical Pathways