precision medicine

Research in Review

Atezolizumab Safely Improves Survival for Patients Previously Treated for Non-Small Cell Lung Cancer

04/01/2016

JCP Editors

Atezolizumab may be a safe and effective option for patients with non-small cell lung cancer (NSCLC) who have progressed on post-platinum chemotherapy, according to results from a phase 2 randomized controlled...

...

04/01/2016

Journal of Clinical Pathways

Research in Review

Gene-Expression Test Cost-Effective for Determining Unknown Tumor Origins

03/31/2016

JCP Editors

The 2000-gene-expression profiling (GEP) test may be a more cost-effective option than current strategies for identifying tumor origin in patients with cancer of unknown primary (CUP), a recent study...

The...

03/31/2016

Journal of Clinical Pathways

Research in Review

HPV-16 Associated with Better Overall Survival in Patients With Head and Neck Cancer

03/31/2016

JCP Editors

The presence of human papillomavirus-16 (HPV-16) is associated with higher rates of overall survival in patients with head and neck squamous cell carcinoma (HNSC), suggesting it may be a more effective prognostic...

The...

03/31/2016

Journal of Clinical Pathways

Guidelines for Bone Scans After Oophorectomy Needed

03/30/2016

JCP Editors

Despite being at a greater risk for bone loss after prophylactic oophorectomy, carriers of BRCA mutations are under-screened for bone mineral density, according to a recent study. Women with BRCA1 or BRCA2 have a...

...

03/30/2016

Journal of Clinical Pathways

Research in Review

Novel Breast Cancer Staging System More Effective for Determining Prognosis

03/22/2016

JCP Editors

Researchers at the University of Texas MD Anderson Cancer Center (Houston, TX) have developed a novel staging system that incorporates tumor biology as a critical prognostic indicator for women with breast cancer who...

...

03/22/2016

Journal of Clinical Pathways

Research in Review

Report Outlines the Path to Improving Biomarker Tests for Targeted Therapies

03/21/2016

JCP Editors

Biomarker tests are not being adequately used in clinical practice due to a lack of common evidentiary standards for regulatory, reimbursement, and clinical decisions regarding their use, according to a report by the...

...

03/21/2016

Journal of Clinical Pathways

Oncologists Call for New Metrics to Evaluate Effectiveness of Novel Treatments

03/17/2016

JCP Editors

At the 33rd Annual Miami Breast Cancer Conference (March 10-11, 2016; Miami Beach, FL), presenters called for new ways to evaluate the success of novel agents for the treatment of breast cancer. Although overall...

At the...

03/17/2016

Journal of Clinical Pathways

Research in Review

Precision Medicine for Hypertension

03/04/2016

JCP Editors

Doctors from the University of Wisconsin (Milwaukee, WI) suggest that precision medicine and epigenetics are two emerging fields that could alter the way in which hypertension is treated. Recent US studies of...

...

03/04/2016

Journal of Clinical Pathways

Research in Review

Pancreatic Cancer May Actually Be Four Distinct Diseases

03/03/2016

JCP Editors

Pancreatic cancer may actually present as four separate diseases, according to a recently published study from the United Kingdom. Prognoses for patients with pancreatic cancer are generally poor because a limited...

...

03/03/2016

Journal of Clinical Pathways

Research in Review

Improving Clinical Management of High-Risk Patients Through "Precision Delivery"

02/29/2016

JCP Editors

Doctors from Brigham and Women’s Hospital (Boston, MA) have proposed that limiting the overuse of costly resources through predictive analytics could help to reduce rising health care costs for high-risk patient...

...

02/29/2016

Journal of Clinical Pathways