outcomes research

Research in Review

Multiple-Treatment Regimens for Colorectal Cancer Have High Costs and Little Benefit to Elderly Patients

03/02/2016

JCP Editors

A 10-year study has found that the rate of elderly patients receiving 3 or more treatments for metastatic colorectal cancer has increased substantially from 2000 to 2009, but that added agents may not lead to...

A...

03/02/2016

Journal of Clinical Pathways

Research in Review

Physician Autonomy in A Value-Based Health Care System

03/01/2016

JCP Editors

In a recently published article, authors argued that the current metrics used for value-based reimbursement in health care are insufficient and that only improved health outcomes can truly measure clinical...

In a...

03/01/2016

Journal of Clinical Pathways

Research in Review

Positron Emission Tomography Overused in Patients With Lung and Esophageal Cancers

02/26/2016

JCP Editors

A study finding significant variation in the use of positron emission tomography (PET) scans, but no association between the number of scans and improved 2-year survival, suggests that the imaging technique might be...

A...

02/26/2016

Journal of Clinical Pathways

Research in Review

Noncompliance with Radiation Therapy Schedules Worsens Outcomes for Patients With Cancer

02/11/2016

JCP Editors

Missing two or more radiation therapy sessions can have severe adverse effects on clinical outcomes, according to a new study. Noncompliance with treatment schedules is a critical issue for many patient populations...

...

02/11/2016

Journal of Clinical Pathways

Research in Review

Intense Tumor Lymphocytic Infiltration Predicts Improved Survival in Patients With NSCLC

02/05/2016

JCP Editors

A new study, published in the Journal of Clinical Oncology, has found that a greater presence of tumor lymphocytic infiltration (TLI) may be associated with a greater likelihood of survival in patients with non-small...

A new...

02/05/2016

Journal of Clinical Pathways

Research in Review

Population-based Study Shows No Significant Effect Of Metformin on Lung Cancer Survival

02/04/2016

JCP Editors

New evidence has revealed that metformin, a popular diabetes medication thought to inhibit the progression of lung cancer, actually has a nonsignificant effect on mortality in patients with lung...

New...

02/04/2016

Journal of Clinical Pathways

Research in Review

Common Outcome Measures for Clinical Trials Are Improving, Study Shows

01/28/2016

JCP Editors

According to a new study, core outcome sets (COS) for clinical trials have become more structured, but there remains a need for greater transparency and public engagement in how COS are developed. Clinical trials...

...

01/28/2016

Journal of Clinical Pathways

Research in Review

Dacomitinib Comparable to Erlotinib in Patients with EGFR+ NSCLC

01/18/2016

JCP Editors

Dacomitinib may be comparable to erlotinib in treating non-small cell lung cancer (NSCLC), specifically in patients that are positive for the epidermal growth factor receptor (EGFR) mutation. Dacomitinib, an...

...

01/18/2016

Journal of Clinical Pathways

Research in Review

Statin Therapy May Improve Survival in Patients with Metastatic SCLC

01/14/2016

JCP Editors

In a retrospective study published in PLoS ONE, researchers found a survival benefit associated with statin use in patients with small cell lung cancer (SCLC) that has spread to other regions of the body. SCLC,...

In a...

01/14/2016

Journal of Clinical Pathways

Research in Review

Suicide Gene Therapy Safe and Effective in Treating Prostate Cancer

12/15/2015

JCP Editors

A long-term clinical trial of suicide gene therapy has shown that it safely and effectively destroys prostate cancer cells. The method alters the genetic composition of cancer cells so that they trigger the immune...

A...

12/15/2015

Journal of Clinical Pathways