outcomes research

Research in Review

HC-Based Next-Gen Sequencing Aids Treatment Decisions in Lung Cancer

11/23/2016

JCP Editors

Hybrid capture (HC)-based next-generation sequencing (NGS) can identify targetable oncogenic drivers to improve response rates in patients with lung cancer, according to a study published in the Journal of Thoracic...

Hybrid...

11/23/2016

Journal of Clinical Pathways

Research in Review

TKI Drug Improves Survival in Metastatic Kidney Cancer

11/22/2016

JCP Editors

First-line therapy with cabozantinib was superior to standard of care sunitinib with respect to progression-free survival and objective response rate for patients with intermediate- or poor-risk metastatic renal cell...

...

11/22/2016

Journal of Clinical Pathways

Research in Review

Incorporating EGFR, ALK Gene Alterations Data Improves Survival Prediction for Patients With NSCLC

11/21/2016

JCP Editors

Patients with non-small cell lung cancer (NSCLC) may see improved survival predictions as a result of a new prognostic tool that includes EGFR and ALK gene alterations data, according to an analysis published...

...

11/21/2016

Journal of Clinical Pathways

Research in Review

Combining Targeted Therapies Provides Optimal Treatment for CML

11/17/2016

JCP Editors

Using mathematical modeling, researchers have determined the best combination and sequencing of targeted therapies for the treatment of chronic myeloid leukemia (CML). Their results have been published in PLOS...

Using...

11/17/2016

Journal of Clinical Pathways

Research in Review

New Treatment Effective for B-Cell Precursor ALL in Pediatric Patients

11/17/2016

JCP Editors

Single-agent blinatumomab demonstrated antileukemia activity in pediatric patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (BCP-ALL), according to a study published in the Journal of...

...

11/17/2016

Journal of Clinical Pathways

Research in Review

Pediatric Stroke Pathway Improves Time to Definitive Diagnosis

11/15/2016

JCP Editors

A pediatric stroke clinical pathway significantly improved time to definitive diagnosis while also streamlining the care provided to children presenting to the pediatric emergency department (ED) with focal...

A...

11/15/2016

Journal of Clinical Pathways

Research in Review

Study Examines Cost-Effectiveness of Treatment Sequencing for HER2-Positive Breast Cancer

11/15/2016

JCP Editors

Targeted therapies have been shown to significantly improve the survival of patients with human epidermal growth factor 2 (HER2)-positive metastatic breast cancer. However, these therapies have also been associated...

...

11/15/2016

Journal of Clinical Pathways

Research in Review

External Beam Radiotherapy Effective for Skin Kaposi Sarcoma Treatment

11/11/2016

JCP Editors

Kaposi Sarcoma (KS) skin lesions are more likely to respond to local external beam radiotherapy than repeat radiotherapy, according to a study conducted by members of the Department of Radiation Oncology, University...

Kaposi...

11/11/2016

Journal of Clinical Pathways

Research in Review

NET Equally Effective, Safer Than Neoadjuvant Chemotherapy for ER+ Breast Cancer

11/11/2016

JCP Editors

Neoadjuvant endocrine therapy may be just as effective as neoadjuvant chemotherapy for patients with localized, estrogen-receptor (ER)-positive breast cancer with considerably fewer adverse events, according to a...

...

11/11/2016

Journal of Clinical Pathways

Quiz

Best Targeted Therapy for Melanoma

11/10/2016

JCP Editors

A study published in JAMA Oncology recently showed that treatment with which of the following drug types was just as effective as BRAF- and MEK-targeted therapies for melanoma and also limited the risk of...

A...

11/10/2016

Journal of Clinical Pathways