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Genetic Testing Underutilized in Women With History of Ovarian Cancer

08/22/2017

JCP Editors

Less than 20% of patients with a history of ovarian cancer meeting National Comprehensive Cancer Network (NCCN) guidelines have undergone genetic testing or have discussed testing with their health care...

Less...

08/22/2017

Journal of Clinical Pathways

Research in Review

Comparative Effectiveness Study Examines Treatment Options for DLBCL

08/18/2017

JCP Editors

A recent study compared the treatment effects and adverse events of first-line chemotherapy regimens in patients with treatment-naïve diffuse large B-cell lymphoma (DLBCL). Rituximab plus cyclophosphamide,...

A...

08/18/2017

Journal of Clinical Pathways

Research in Review

Patient Values, Concerns Influence Breast Cancer Treatment Decisions

08/17/2017

JCP Editors

Researchers examined the decision-making processes of patients with breast cancer to understand why a procedure that does not improve survival is increasingly being considered. ----- Related Content Contralateral...

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08/17/2017

Journal of Clinical Pathways

Research in Review

Resistance Mutations Predict Metastatic Patterns in NSCLC

08/17/2017

JCP Editors

Specific gene rearrangements associated with increased resistance to standard therapy may predict different metastasis distributions in patients with non-small cell lung cancer (NSCLC), according to research...

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08/17/2017

Journal of Clinical Pathways

Research in Review

Monotherapy Improves Outcomes in Metastatic Breast Cancer With BRCA Mutation

08/14/2017

JCP Editors

An immuno-agent improves progression-free survival (PFS) and lowers the risk of death for patients with human epidermal growth factor 2 (HER2)-negative metastatic breast cancer and a germline BRCA mutation, according...

An...

08/14/2017

Journal of Clinical Pathways

Research in Review

Pancreatic Cancer Guidelines Do Not Cover Some Targetable Mutations

08/11/2017

JCP Editors

Germline mutations in pancreatic cancer susceptibility genes are often identified in patients with pancreatic cancer without a known family history of cancer, according to a recent study. ----- Related...

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08/11/2017

Journal of Clinical Pathways

Research in Review

Double Dosage of ALK Inhibitor Improves Outcomes in NSCLC

08/09/2017

JCP Editors

Increasing the standard dose of an anaplastic lymphoma kinase (ALK) inhibitor for the treatment of non-small cell lung cancer (NSCLC) improves objective response rates (ORR) by 9% with limited additional toxicity,...

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08/09/2017

Journal of Clinical Pathways

Research in Review

Pediatric APL Outcomes Improved By Arsenic Trioxide Consolidation

08/03/2017

JCP Editors

Consolidation with arsenic trioxide allows for decreased anthracycline dosing while maintaining survival rates and a low risk of relapse in pediatric patients with acute promyelocytic leukemia (APL), according to a...

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08/03/2017

Journal of Clinical Pathways

Research in Review

Advance Directives, QoL-Focused Care Needed for Cancer Patients With Delirium in the ED

08/03/2017

JCP Editors

Patients with advanced cancer who visit the emergency department (ED) with delirium have increased rates of hospitalizations and ICU admissions, along with decreased survival rates, according to a recent study...

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08/03/2017

Journal of Clinical Pathways

Research in Review

Dose Escalation of CML Treatment Improves Molecular Response Rates

08/02/2017

JCP Editors

Patients with chronic myeloid leukemia (CML) in the chronic phase may achieve molecular response with safe and effective treatment dose escalation, according to a recent study. ----- Related Content CML Mutations...

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08/02/2017

Journal of Clinical Pathways