comparative effectiveness

Research in Review

Monotherapy Improves Outcomes in Metastatic Breast Cancer With BRCA Mutation

08/14/2017

JCP Editors

An immuno-agent improves progression-free survival (PFS) and lowers the risk of death for patients with human epidermal growth factor 2 (HER2)-negative metastatic breast cancer and a germline BRCA mutation, according...

An...

08/14/2017

Journal of Clinical Pathways

Research in Review

Costs and Complications Associated With Repeated Breast-Conserving Surgery for Breast Cancer

08/09/2017

JCP Editors

More than 23% of patients with breast cancer who undergo breast-conserving surgery followed by subsequent surgery do not receive the full benefits of surgery due to added costs and complications, according...

More...

08/09/2017

Journal of Clinical Pathways

Research in Review

Internal Radiotherapy Combined With Chemo in Colorectal Liver Metastasis

08/09/2017

JCP Editors

A recent study combined and analyzed data from three trials regarding the use of first-line chemotherapy plus selective internal radiotherapy in patients with colorectal cancer and liver metastases, published in The...

A...

08/09/2017

Journal of Clinical Pathways

Research in Review

Combination Therapy Improves Survival in a Subtype of AML

08/04/2017

JCP Editors

Addition of a multi-targeted kinase inhibitor to standard chemotherapy improves outcomes in patients with acute myeloid leukemia (AML) and a specific mutation, according to research published in The New England...

...

08/04/2017

Journal of Clinical Pathways

Research in Review

Immunotherapy Better Than Standard of Care for Type of DLBCL

08/03/2017

JCP Editors

Single-agent immunotherapy in patients with a subtype of relapsed or refractory diffuse large B-cell lymphoma (DLBCL) provides more clinical benefit than conventional therapy, according to research published in...

...

08/03/2017

Journal of Clinical Pathways

Research in Review

Pediatric APL Outcomes Improved By Arsenic Trioxide Consolidation

08/03/2017

JCP Editors

Consolidation with arsenic trioxide allows for decreased anthracycline dosing while maintaining survival rates and a low risk of relapse in pediatric patients with acute promyelocytic leukemia (APL), according to a...

...

08/03/2017

Journal of Clinical Pathways

Research in Review

Cost-Effectiveness of Multiple Myeloma Therapies From a Payer‚Äôs Perspective

08/02/2017

JCP Editors

A recent cost-effectiveness analysis compared novel agents and chemotherapy for older Medicare patients with multiple myeloma, published in the Journal of Managed Care & Specialty Pharmacy (August...

A...

08/02/2017

Journal of Clinical Pathways

Research in Review

Lymphocyte Biomarkers Predict PFS in HER2-Positive Breast Cancer

07/31/2017

JCP Editors

A low level of stromal cytotoxic T-cell infiltration in breast cancer tumor specimens predicts patients who may benefit most from antibody- vs molecular-based human epidermal growth factor receptor 2 (HER2)...

A low...

07/31/2017

Journal of Clinical Pathways

Research in Review

Clinical Trial Efficacy Consistent with Real-World Outcomes, Study Shows

07/28/2017

JCP Editors

Researchers compared the relationship between randomized controlled clinical trial efficacy data and real-world effectiveness for oncology therapies, published in Value in Health (July-August,...

...

07/28/2017

Journal of Clinical Pathways

Research in Review

NSCLC Prognostic Index Considers Personal Characteristics to Better Predict Outcomes

07/26/2017

JCP Editors

The Lung Cancer Prognostic Index provides personalized and disease-specific prognostic information for patients with non-small cell lung cancer (NSCLC) and may result in better survival outcomes, according to a...

The...

07/26/2017

Journal of Clinical Pathways