population health

Research in Review

Dose Adjustment Reduces AEs Without Impacting Efficacy in NSCLC

09/14/2016

JCP Editors

Tolerability-guided dose adjustment is an effective measure to reduce afatinib (Giotrif)-related adverse events (AEs) without affecting therapeutic efficacy in patients with non–small cell lung cancer (NSCLC),...

...

09/14/2016

Journal of Clinical Pathways

Research in Review

Evidence for Liquid Biopsy Use in Lung Cancer Grows

09/14/2016

JCP Editors

A non-invasive liquid biopsy may be more effective at detecting clinically relevant mutations in patients with advanced lung cancer than standard biopsies, according to a study published in the journal Clinical...

A...

09/14/2016

Journal of Clinical Pathways

Research in Review

HAPs Prevent Treatment Resistance in EGFR+ NSCLC

09/12/2016

JCP Editors

Adding a hypoxia-activated prodrug (HAP) to standard care for epidermal growth factor receptor-positive non-small cell lung cancer may help to delay treatment resistance, according to a study published in PLOS...

Adding...

09/12/2016

Journal of Clinical Pathways

Research in Review

Vinblastine for Low-Grade Glioma Has Few Side Effects and Comparable Survival

09/09/2016

JCP Editors

Vinblastine monotherapy has similar outcomes and a more favorable toxicity profile compared with current therapies when used in patients with treatment naïve pediatric low-grade glioma (PLGG), according to a study...

...

09/09/2016

Journal of Clinical Pathways

Research in Review

Response-Guided Neoadjuvant Chemotherapy Cost Effective for Breast Cancer

09/07/2016

JCP Editors

Response-guided neoadjuvant chemotherapy (RG-NACT) is more cost effective than conventional NACT for estrogen receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer, according...

...

09/07/2016

Journal of Clinical Pathways

Research in Review

Barriers Predict Nonadherence to Treatment for Early-Stage Breast Cancer

09/06/2016

JCP Editors

Perceived barriers to treatment may predict patient nonadherence to aromatase inhibitors for women with early-stage, estrogen receptor-positive breast cancer, claims a study published in Cancer. While patient...

...

09/06/2016

Journal of Clinical Pathways

Research in Review

Study Identifies Financial Ties Among NCCN Guideline Authors and Drug Industry

09/02/2016

JCP Editors

A new study that quantifies industry financial conflicts of interest (FCOIs) found that nearly nine out of 10 physicians and researchers who helped develop the National Comprehensive Network (NCCN) guidelines—work...

A new...

09/02/2016

Journal of Clinical Pathways

Research in Review

70-Gene Signature Aids Breast Cancer Decision-Making

08/30/2016

JCP Editors

The 70-gene signature test may help patients with early-stage breast cancer avoid unneeded chemotherapy, according to the results of a study published in The New England Journal of Medicine. The 70-gene signature...

The...

08/30/2016

Journal of Clinical Pathways

Research in Review

Levetiracetam Superior to Other Anti-Epileptic Drugs in Elderly Patients

08/29/2016

JCP Editors

Elderly patients taking levetiracetam (LEV) may exhibit longer time to treatment withdrawal than those treated with standard anti-epileptic drugs (AEDs), according to a study published in BMC Neurology. Health care...

...

08/29/2016

Journal of Clinical Pathways

Research in Review

Elective Neck Dissection Cost-Effective in Oral Cavity Cancer

08/26/2016

JCP Editors

A cost-effective analysis found that the addition of elective neck dissection to primary surgery in patients with oral cavity cancer showed a cost reduction and improved health outcomes, reported researchers from the...

A...

08/26/2016

Journal of Clinical Pathways