prostate cancer

Research in Review

Novel Prostate Cancer Biomarkers May Improve Targeted Therapy

08/15/2017

JCP Editors

Recent research has uncovered a new cause of treatment resistance in prostate cancer, which may improve targeted therapy efforts. Mutations within the SPOP gene are the most frequently documented genetic changes in...

Recent...

08/15/2017

Journal of Clinical Pathways

Research in Review

ADT Plus Combination Therapy Improves Outcomes in Metastatic Prostate Cancer

07/28/2017

JCP Editors

A combination regimen plus androgen-deprivation therapy prolongs overall survival (OS) and radiographic progression-free survival (PFS) in newly diagnosed patients with metastatic, castration-sensitive prostate...

A...

07/28/2017

Journal of Clinical Pathways

Research in Review

Is Active Surveillance Beneficial for Patients With Intermediate-Risk Prostate Cancer?

07/20/2017

JCP Editors

Recent research explored the potential of a subset of patients with intermediate-risk prostate cancer likely to benefit from active surveillance. Active surveillance is currently recommended for patients with...

Recent...

07/20/2017

Journal of Clinical Pathways

Research in Review

Prostate Cancer Scanning Helps Detect Further Disease, Improve Care

06/28/2017

JCP Editors

Positron emission tomography (PET) and computed tomography (CT) scans specific to prostate cancer can detect further disease and improve clinical management, according to recent research. Ga68-Prostate Specific...

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06/28/2017

Journal of Clinical Pathways

Research in Review

Active Surveillance Use for Prostate Cancer Varies at Practice and Physician Level

06/22/2017

JCP Editors

Quality improvements are needed to help optimize the implementation of active surveillance among urologists and practice settings, according to a research letter published in JAMA Surgery (published online June 21,...

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06/22/2017

Journal of Clinical Pathways

Research in Review

Can Active Surveillance Benefit Younger Patients With Prostate Cancer?

06/19/2017

JCP Editors

Research suggests that age can impact the risk of disease progression in low-risk prostate cancer managed with active surveillance, published in the Journal of Clinical Oncology (June 2017;35[17]:1898-1904). Recent...

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06/19/2017

Journal of Clinical Pathways

Research in Review

Prostate Cancer Testing Guidelines Omit Critical Genetic Features

06/13/2017

JCP Editors

Current National Comprehensive Cancer Network (NCCN) guidelines and Gleason scores cannot reliably stratify patients with risk of prostate cancer for the presence or absence of pathogenic germline variants,...

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06/13/2017

Journal of Clinical Pathways

Research in Review

Metastatic Hormone-Na√Øve Prostate Cancer Effectively Treated With Combination Therapy

06/07/2017

JCP Editors

Groundbreaking results of a trial have shown that the combination of a new drug with androgen deprivation therapy (ADT) significantly improves overall survival (OS) and radiographic progression-free survival (PFS) in...

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06/07/2017

Journal of Clinical Pathways

Research in Review

Microbiome Signature Helps Predict Prostate Cancer

06/01/2017

JCP Editors

Transcriptome sequencing that identifies pathogens in prostate cancer biopsies can be used as a signature for disease detection, according to research presented at the 2017 ASCO Annual Meeting (June 2-6, 2017;...

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06/01/2017

Journal of Clinical Pathways

Research in Review

Cost-Effectiveness Analysis Reveals Optimal Screening Strategy for Prostate Cancer

05/23/2017

JCP Editors

A diagnostic magnetic resonance imaging (MRI) scan followed by an MRI-guided biopsy strategy is more cost-effective than an invasive transrectal ultrasound for detecting prostate cancer, according to research...

A...

05/23/2017

Journal of Clinical Pathways