combination therapy

Research in Review

Neratinib Delays Recurrence With Fewer Metastases in Patients With Breast Cancer

04/29/2016

JCP Editors

Results from a phase 2 clinical trial showed that combination neratinib and paclitaxel treatment better managed central nervous system progression versus trastuzumab and paclitaxel in patients with ERBB2-positive...

...

04/29/2016

Journal of Clinical Pathways

TGFŒ≤ Pathway Inhibitor Improves Survival in Patients With Pancreatic Cancer

04/22/2016

JCP Editors

Galunisertib plus gemcitabine may improve overall survival and progression-free survival compared to gemcitabine alone in patients with pancreatic cancer, according to a study presented at the American Association...

...

04/22/2016

Journal of Clinical Pathways

Research in Review

Aspirin Reduces Mortality by 20% in Patients With Colon Cancer

04/21/2016

JCP Editors

Adding aspirin to cancer treatment regimens can reduce mortality by 20% in patients with colon cancer, according to a meta-analysis published in PLOS One. Previous studies have linked low-dose aspirin use to a...

Adding...

04/21/2016

Journal of Clinical Pathways

Research in Review

Adding Chemotherapy to Radiation Therapy Improves Long-Term Outcomes for Patients With Low-Grade Brain Tumors

04/08/2016

JCP Editors

The combination of chemotherapy and radiation therapy may improve progression-free survival (PFS) and overall survival in patients with grade 2 glioma, according to a recent study. Glioma is a form of brain cancer...

The...

04/08/2016

Journal of Clinical Pathways

NCCN Announces Changes to Guidelines for NSCLC

04/06/2016

JCP Editors

New guidelines for non-small cell lung cancer (NSCLC) recommend testing for epidermal growth factor receptor (EGRF) mutations as a part of routine care for patients diagnosed with non-small cell lung cancer (NSCLC),...

New...

04/06/2016

Journal of Clinical Pathways

Major Changes to NCCN Guidelines for Multiple Myeloma Announced

04/05/2016

JCP Editors

The National Comprehensive Cancer Network (NCCN) has announced three major changes to its guidelines for the treatment of multiple myeloma (MM) that broaden the population of patients eligible to start therapy,...

The...

04/05/2016

Journal of Clinical Pathways

Research in Review

Drug Combinations Cost-Effective for Reducing Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma

03/08/2016

JCP Editors

A study comparing seven prophylaxis strategies for reducing the risk of febrile neutropenia (FN) in patients with non-Hodgkin lymphoma receiving chemotherapy found that routine primary prophylaxis (PP) with...

...

03/08/2016

Journal of Clinical Pathways

Research in Review

Multiple-Treatment Regimens for Colorectal Cancer Have High Costs and Little Benefit to Elderly Patients

03/02/2016

JCP Editors

A 10-year study has found that the rate of elderly patients receiving 3 or more treatments for metastatic colorectal cancer has increased substantially from 2000 to 2009, but that added agents may not lead to...

A...

03/02/2016

Journal of Clinical Pathways

Research in Review

Palliative Drugs In Combination With Docetaxel Can Improve Prostate Cancer Care

02/23/2016

JCP Editors

A clinical trial has shown that combining the chemotherapy drug docetaxel with other treatments can improve clinical outcomes in patients with bony metastatic castrate-refractory prostate cancer (CRPC). The...

A...

02/23/2016

Journal of Clinical Pathways

Research in Review

Predictive Biomarker for Panitumumab Therapy Effectiveness in Patients With Colorectal Cancer

02/12/2016

JCP Editors

Expression of epidermal growth factor receptor ligands epiregulin (EREG) and amphiregulin (AREG) may help determine which patients with colorectal cancer are the most likely to benefit from panitumumab therapy. The...

...

02/12/2016

Journal of Clinical Pathways