combination therapy

Interview

Novel Ibrutinib Combination for Primary Treatment of CLL

06/22/2020

On April 21, 2020, the FDA expanded its approval of ibrutinib to include its use in combination with rituximab for the primary treatment of adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma...

On...

06/22/2020

Journal of Clinical Pathways

News

HRQoL of Patients With Heavily Pretreated or Renally Impaired Multiple Myeloma

06/18/2020

Isatuximab in combination with pomalidomide and dexamethasone may provide an effective treatment option in relapsed or refractory multiple myeloma, including difficult-to-treat subgroups of these patients, and may...

...

06/18/2020

Journal of Clinical Pathways

News

Practice-Changing Clinical Trials in Metastatic Colorectal Cancer

05/30/2020

Autumn J McRee, MD, associate professor of medicine, The University of North Carolina at Chapel Hill, presented on three clinical studies of targeted therapies in unique niches of metastatic colorectal cancer. The...

Autumn...

05/30/2020

Journal of Clinical Pathways

Feature

Current State of Myelodysplastic Syndromes: Standard Treatment Practices and Therapeutic Advances

08/19/2019

Mark G Faber, DO

Elizabeth A Griffiths, MD

Swapna Thota, MD

Abstract: Patients with myelodysplastic syndromes (MDS) collectively have a high symptom burden and are also at risk of death from complications of cytopenias and acute myeloid leukemia. The goals of therapy for...

...

08/19/2019

Journal of Clinical Pathways

Research in Review

Neoadjuvant Chemotherapy May Induce Breast Cancer Metastasis

07/10/2017

JCP Editors

A neoadjuvant chemotherapy combination used to treat breast cancer increases the risk of disease metastasis, according to recent research published in Science Translational Medicine (published online July 5, 2017;...

A...

07/10/2017

Journal of Clinical Pathways

Research in Review

DLBCL Survival Outcomes Improved With Combination Therapy

06/22/2017

JCP Editors

Patients with diffuse large B-cell lymphoma (DLBCL) benefit from improved survival outcomes when treated with a combination therapy rather than monotherapy, according to research presented at the 22nd Congress of the...

...

06/22/2017

Journal of Clinical Pathways

Research in Review

Comparative Effectiveness Study Examines Treatment Options for Type of Colorectal Cancer

06/22/2017

JCP Editors

A recent study compared the effects of first-line chemotherapy with two different drugs in patients with advanced or metastatic colorectal cancer, published in JAMA (2017;317[23]:2392-2401). ----- Related...

A...

06/22/2017

Journal of Clinical Pathways

Gemcitabine-Based Chemoradiation Effective Bladder Cancer Treatment for Underdeveloped Nations

06/04/2017

JCP Editors

Neoadjuvant gemcitabine-based chemotherapy, followed by gemcitabine-based concomitant chemoradiation, may aid in bladder preservation for patients receiving treatment for muscle-invasive bladder cancer in...

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06/04/2017

Journal of Clinical Pathways

Research in Review

Combined Chemotherapy, Radiation Improves Survival in Locally Advanced Pancreatic Cancer

06/03/2017

JCP Editors

The addition of radiation therapy to chemotherapy improved overall survival (OS) in patients with unresected locally advanced pancreatic cancer, according to research presented at the 2017 ASCO Annual Meeting (June...

The...

06/03/2017

Journal of Clinical Pathways

Research in Review

Previous Radiotherapy Improves Response to Immunotherapy in NSCLC

05/30/2017

JCP Editors

Patients with advanced non-small cell lung cancer (NSCLC) who receive previous radiotherapy are more likely to benefit from immunotherapy than those patients without previous radiotherapy, according to research...

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05/30/2017

Journal of Clinical Pathways