Chenguang Li, MD, PhD1; Jing Wu, MS2; Jiayan Lin, BS3; Yizhe Wu, MD, PhD1; Rende Xu, MD, PhD1; Juying Qian, MD, PhD1; William Kongto Hau, PhD4; Emanuele Barbato, MD, PhD5,6; Nils P. Johnson, MD, MS7,8; Barry Hennigan, MBBChBAO, BMedSci9; Colin Berry, MBChB, MD, PhD9,10; Keith G. Oldroyd, MBChB, MD (Hons)9; Liang Song, PhD3; Junbo Ge, MD, PhD1